A5101666609- Mosquito-borne diseases and control
- Pelvic and Acetabular Injuries
- Viral Infections and Vectors
- Malaria Research and Control
- Pelvic floor disorders treatments
- T-cell and B-cell Immunology
- Blood donation and transfusion practices
- Bioactive natural compounds
- Cancer-related molecular mechanisms research
- CAR-T cell therapy research
- Liver Disease and Transplantation
- Erythrocyte Function and Pathophysiology
- Antifungal resistance and susceptibility
- NF-κB Signaling Pathways
- RNA modifications and cancer
- Bacterial biofilms and quorum sensing
- Biomedical Ethics and Regulation
- Flavonoids in Medical Research
- Pluripotent Stem Cells Research
- Organ Transplantation Techniques and Outcomes
- Pregnancy-related medical research
- Synthesis of Indole Derivatives
- Immune Response and Inflammation
- Academic Publishing and Open Access
- Hernia repair and management
First Affiliated Hospital of Guangzhou Medical University
2019-2021
Guangzhou Medical University
2019-2021
Qilu Hospital of Shandong University
2017-2019
Shanghai Blood Center
2009-2018
Southern Medical University
2013
Zhujiang Hospital
2013
Army Medical University
2006
Two antibodies against flaviviruses Flaviviruses are a group of RNA viruses that include the human pathogens dengue virus, Zika and West Nile virus. The envelope protein (E) on virus surface has been target vaccine development, but problems have arisen with E, leading to enhanced infection. Now, Modhiran et al. Biering describe two different bind flavivirus NS1 prevent it from disrupting epithelial cells, which is associated severe disease. Both cross-react multiple proteins. reduce viremia...
BACKGROUND:Hypoxia induces cell apoptosis in the uterosacral ligaments of patients with pelvic organ prolapse by upregulation hypoxia-inducible factor-1α (HIF-1α). This study aimed to investigate effects HIF-1α on human ligament fibroblasts (hUSLFs) following treatment chemical inducer hypoxia, cobalt chloride (CoCl2), and explore underlying mechanisms. MATERIAL AND METHODS:Ten women who underwent hysterectomy for benign disease provided tissue extraction. Following CoCl₂ treatment,...
Activation of the FOXM1 signaling pathway and PI3K/AKT/mTOR is associated with poor prognosis in ovarian cancer. In this study, we demonstrated that P15 PAF (KIAA0101) was significantly upregulated high‐grade serous cancer (HGSOC) high KIAA0101 expression prognosis. transcriptionally activated to drive proliferation metastasis cells. inhibit cisplatin‐induced apoptosis autophagy cells resulting cisplatin resistance. Thus, closely related pathways. Collectively, these findings provide...
As the most frequent fungal pathogen in humans, Candida albicans can develop serious drug resistance because its biofilms are resistant to antifungal agents; this leads an urgent need novel antifungals. Here, we evaluated efficacy of antithrombotic drug, suloctidil, against C. vitro and vivo. We found that suloctidil is effective inhibit biofilm, with a minimum inhibitory concentration (MIC80) 4 μg/mL, biofilm inhibiting (BIC80) 16 μg/mL eradicating (BEC80) 64 μg/mL. Furthermore,...
The purpose of this study is to evaluate the expression hypoxia-inducible factor-1 α (HIF-1 ) in women uterosacral ligament tissues with pelvic organ prolapse and normal uterine support structures illuminate its relationship apoptosis. Samples were collected from 38 31 age matched controls. levels HIF-1 BNIP3 ligaments measured using immunohistochemistry, qRT-PCR, Western blot. To assess apoptosis we performed TUNEL assay blot analyses. Lastly, short form Pelvic Floor Impact Questionnaire-7...
Objective. Tolerogenic dendritic cells (tDCs) can expand TGF- β -induced regulatory T (iTregs); however, the therapeutic utility of these expanded iTregs in autoimmune diseases remains unknown. We sought to determine properties by mature tolerogenic (iTreg mtDC ) vitro and explore their potential ameliorate collagen-induced arthritis (CIA) a mouse model. Methods . After induction expansion tDCs (mtDCs), phenotype proliferation iTreg were assessed flow cytometry. The ability inhibit CD4 +...
Objective To evaluate the importance of alanine minotransferase (ALT) testing performance to blood safety assurance in Chinese BTSs. Methods There were 565 360 donors who participated donation two times within 365 days from Feb. 2006 Jan. 2008 Shanghai. These divided into groups, namely ALT deferred and qualified donors. The secondtime screening results those groups analyzed statistically. Results reactive ratio ALT, HBsAg, anti-HCV, Syphilis overall disqualification among 33.90％, 0.38％,...