- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Bacterial Genetics and Biotechnology
- Aquaculture disease management and microbiota
- Microbial Metabolism and Applications
- Probiotics and Fermented Foods
- RNA and protein synthesis mechanisms
- Enzyme Structure and Function
- Gut microbiota and health
- Protein Hydrolysis and Bioactive Peptides
- Protease and Inhibitor Mechanisms
- Cancer Research and Treatments
- Enzyme Production and Characterization
- CRISPR and Genetic Engineering
- Salmonella and Campylobacter epidemiology
- Marine Sponges and Natural Products
- Microbial Metabolites in Food Biotechnology
- Plant Disease Resistance and Genetics
- Antioxidant Activity and Oxidative Stress
- Algal biology and biofuel production
- DNA Repair Mechanisms
Thailand Institute of Scientific and Technological Research
2006-2020
Waters (United Kingdom)
2013
University of Sheffield
2011-2013
University of Nottingham
2013
Abstract Taxonomic and functional research of microorganisms has increasingly relied upon genome-based data methods. As the depository Global Catalogue Microorganisms (GCM) 10K prokaryotic type strain sequencing project, Type Strain (gcType) published 1049 genomes sequenced by GCM project which are preserved in global culture collections with a valid status. Additionally, information provided through gcType includes >12 000 publicly available genome sequences from GenBank incorporated...
Three strains of gliding bacteria, 24(T), 62 and 71, isolated from a marine sponge algae the southern coastline Thailand, were studied using polyphasic approach to clarify their taxonomic positions. A phylogenetic analysis based on 16S rRNA gene sequences showed that three isolates formed distinct lineage within family 'Saprospiraceae' phylum Bacteroidetes related members genus Saprospira. The G+C contents in range 38-39 mol%. major respiratory quinone was MK-7. predominant cellular fatty...
Streptococcus mutans predominantly creates an acidic environment in oral cavity. This results dental demineralization and carious lesions. The probiotics are beneficial microorganisms that modulate the bacterial balance digestive system. Prebiotics defined as nondigestible oligosaccharides utilized for selective stimulation of microorganisms. objective this study was to evaluate efficacy prebiotics, galactooligosaccharides (GOS) fructooligosaccharides (FOS), enhancing probiotic Lactobacillus...
The PEB4 protein is an antigenic virulence factor implicated in host cell adhesion, invasion, and colonization the food-borne pathogen Campylobacter jejuni. peb4 mutants have defects outer membrane assembly thought to act as a periplasmic chaperone. crystallographic structure of at 2.2-Å resolution reveals dimer with distinct SurA-like chaperone peptidyl-prolyl cis/trans isomerase (PPIase) domains encasing large central cavity. Unlike SurA, domain formed by interlocking helices from each...
A novel gliding marine bacterium (strain 59SA(T)) was isolated from barnacle debris. phylogenetic analysis based on 16S rRNA gene sequences showed that the isolate formed a distinct lineage within genus Aureispira in family 'Saprospiraceae'. The DNA G+C content of strain 59SA(T) 38.7 mol%, major respiratory quinone MK-7 and predominant cellular fatty acids were 20 : 4omega6c 16 0. On basis data DNA-DNA hybridization, physiological chemotaxonomic analyses sequence comparisons, represents...
A novel gliding bacterial strain, GB 56.1T, was obtained from soil at the Sakaerat Biosphere Reserve, in Nakhon Ratchasima province, Thailand; strain characterized using a polyphasic approach. Cells were Gram-stain-negative, yellow, rod shaped and devoid of flagella, but showed motility. Phylogenetic analysis based on 16S rRNA gene sequences found that 56.1T member genus Flavobacterium shared highest sequence similarities with nitrogenifigens (98.4 %), anhuiense(98.3 %) ginsenosidimutans...
The clamp-loader complex plays a crucial role in DNA replication by loading the β-clamp onto primed to be used replicative polymerase. Relatively little is known about stoichiometry, structure and assembly pathway of this complex, how it interacts with helicase, Gram-positive organisms. Analysis full partial complexes mass spectrometry revealed that hetero-pentameric τ 3 -δ-δ′ Bacillus subtilis assembles via multiple pathways, which differ from those exhibited Gram-negative model Escherichia...
To investigate the efficiency of natural astaxanthin that has been extracted from Xanthophyllomyces dendrorhous in inhibiting proliferation and viability colorectal adenocarcinoma cell line (Caco-2; colon cancer cells).Caco-2 cells normal human oralkeratinocytes (NOKs) were treated with different concentrations astaxanthin, ranging 0.075 to 10 mg ml-1, for 24, 48 72 h. The number was determined via MTS assay proliferating investigated by bromodeoxyuridine (BrdU) assay.Results/Key findings....
A novel bacterial strain, designated hydD52T, was isolated from a sample of tidal flat sediment the Yellow Sea in Republic Korea. The cells were motile, rod-shaped and Gram-stain-negative. Phylogenetic analysis based on 16S rRNA gene sequences revealed that strain hydD52T member genus Sulfitobacter most closely related to dubius DSM 16472T (98.0 %), indolifex HEL-45T (97.8 %) delicatus 28223T (97.6 %). major fatty acids (>5 C18 : 1ω7c/C18 1ω6c, C16 0, 1ω7c 11-methyl C19 0ω8c. respiratory...
This study reports on the complete genome sequence of Spirosoma sp. strain KCTC 42546, isolated from fresh water in a reservoir South Korea. The contained genes for various glycosyl hydrolases, which are associated with degrading sugars and DNA-repairing enzymes.