A5017524749- Forensic Toxicology and Drug Analysis
- Cardiovascular Effects of Exercise
- SARS-CoV-2 and COVID-19 Research
- Opioid Use Disorder Treatment
- Cannabis and Cannabinoid Research
- COVID-19 Clinical Research Studies
- Cardiac electrophysiology and arrhythmias
- Heme Oxygenase-1 and Carbon Monoxide
- Long-Term Effects of COVID-19
- Viral Infections and Immunology Research
- Autopsy Techniques and Outcomes
- Healthcare cost, quality, practices
- Pain Mechanisms and Treatments
- COVID-19 and healthcare impacts
- Medical Malpractice and Liability Issues
- Frailty in Older Adults
- S100 Proteins and Annexins
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury Research
- Patient Safety and Medication Errors
- Pain Management and Opioid Use
- Hormonal and reproductive studies
- Ultrasound in Clinical Applications
- Artificial Intelligence in Healthcare and Education
- Poisoning and overdose treatments
University of Trieste
2020-2025
St George’s University Hospitals NHS Foundation Trust
2024
St George's, University of London
2023-2024
University of Ferrara
2023
The University of Texas Health Science Center at Houston
2023
Creative Research Enterprises (United States)
2023
Ospedale Santa Maria della Misericordia di Udine
2023
Sapienza University of Rome
2022
In the context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, significant attention was given to pulmonary manifestations. However, cardiac involvement is increasingly recognized as a critical factor influencing prognosis, leading myocardial damage, heart failure, coronary syndromes, potentially lethal arrhythmic events, and sudden death. Despite these findings, there lack studies detailing necroscopic, macroscopic, microscopic changes associated with SARS-CoV-2....
Abstract Aims Sudden cardiac death (SCD) may occur in apparently healthy individuals, including athletes. The aim was to investigate the diagnostic role of post-mortem genetic testing, molecular autopsy (MA), elucidating cause SCD Methods and results We reviewed a database 6860 consecutive cases referred our specialist pathology centre. All underwent detailed autopsy, 748 were deemed be Of these, 42 (6%) investigated with MA (28 using targeted sequencing, 14 exome sequencing). Variants...
The relationship between ethnicity and causes of sudden cardiac death (SCD) in athletes is poorly understood. To investigate aetiology SCD among different ethnicities a large cohort athletes. Between 1994 November 2022, 7880 cases were consecutively referred from all over the United Kingdom to our national pathology centre; 848 (11%) All underwent detailed autopsy evaluation by expert pathologists. Clinical information was obtained referring coroners. Most white (n = 758; 89%). Black Asian...
Bile has emerged as an alternative matrix for toxicological investigation of drugs in suspected forensic cases overdose adults and intoxications children. Toxicological consists screening and, subsequently, confirming the result with specific techniques, such liquid chromatography tandem mass spectrometry (LC-MS/MS). As there is no test on market to postmortem bile specimens, novelty this study was investigating applicability a chemiluminescence immunoassay, designed other matrices available...
Since its early spread, the COVID-19 pandemic has become a health threat globally. Due to their crucial role in pandemic, Italy declared compulsory vaccination for healthcare workers. Vaccine hesitancy was observed among workers and an ethical debate arose about Italian legal statement D.L. n. 44/2021. In this article, we present results of survey performed center maternal infant care assess attitudes towards mandatory March 2022, 91.5% have been vaccinated with additional dose. Only 2.3%...
The forensic investigation of asphyxia deaths still poses a challenge due to the need demonstrate vital exposure hypoxic insult according high levels evidence. pulmonary effects hypoxia are complex and understanding mechanisms underlying acute pneumotoxicity induced by is incomplete. Redox imbalance has been suggested as protagonist main changes in function context. development knowledge biochemistry molecular biology allowed research pathology identify some markers useful...
Transdermal fentanyl patches represent an excellent alternative for the treatment of chronic and cancer-related pain, but can lead to death due their incorrect use or increasing abuse. Present overview literature regarding patch related fatalities. Literature research into PubMed database all types publications. Search terms were "fentanyl", "patch" "death". Additional publications by manual examination references results included. To date 29 about transdermal deaths are available on time...
Autopsy is a valuable tool for understanding the physiopathology of any disease, and it gold standard to assess cause death. The clinical autopsy ultimate medical service patient plays crucial role in context quality control, education physicians other personnel, as well mitigation risk malpractice claims.This study aims demonstrate importance improving an relevance this investigation procedure daily practice by evaluating rate major discrepancies between assumed death ascertained after...
There is increasing evidence of cardiac involvement in COVID-19 cases, with a broad range clinical manifestations spanning from acute life-threatening conditions such as ventricular dysrhythmias, myocarditis, myocardial ischemia and pulmonary thromboembolism to long-term cardiovascular sequelae. In particular, myocarditis represents an uncommon but frightening complication SARS-CoV-2 infection. Even if many reports SARS CoV-2 are present the literature, majority them lacks histological...
Fat Embolism Syndrome (FES) is a clinical condition characterized by neurological, respiratory, hematological and cutaneous manifestations. Fatal FES has been described as rare complication during or after spinal elective surgery. The investigation of the cause death in fatalities related with spine surgery should be mandatory to exclude confirm fat embolism; detailed methodological approach body these cases suggests provide cautious dissection surgical site collection samples detect...