A5069170283- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Cardiac pacing and defibrillation studies
- Viral Infections and Immunology Research
- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Acute Myocardial Infarction Research
- Vitamin D Research Studies
- Coronary Interventions and Diagnostics
- Alzheimer's disease research and treatments
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Diet and metabolism studies
- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Neurological disorders and treatments
- Diabetes Treatment and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Gut microbiota and health
- Signaling Pathways in Disease
- Vitamin C and Antioxidants Research
- Ultrasound in Clinical Applications
University of Trieste
2019-2024
Azienda Sanitaria Universitaria Integrata di Trieste
2019-2024
Ospedale Santa Maria della Misericordia di Udine
2022
ERN GUARD-Heart
2022
Diverse genetic backgrounds often lead to phenotypic heterogeneity in cardiomyopathies (CMPs). Previous genotype-phenotype studies have primarily focused on the analysis of a single phenotype, and diagnostic prognostic features CMP genotype across different expressions remain poorly understood.We sought define differences outcome prediction when stratifying patients based phenotype at presentation compared with large cohort CMPs positive testing.Dilated cardiomyopathy (DCM), arrhythmogenic...
Prognostic stratification of acute myocarditis (AM) presenting with normal left ventricular ejection fraction (LVEF) relies mostly on late gadolinium enhancement (LGE) characterization. Left peak global longitudinal strain (LV-GLS) measured by feature tracking analysis might improve prognostication AM LVEF.Data patients undergoing cardiac magnetic resonance (CMR) for clinically suspected in seven European Centres (2013-2020) were retrospectively analysed. Patients confirmed CMR and LVEF ≥50%...
Acute myocardial infarction (AMI) survivors are at risk of major adverse cardiac events and their stratification is a prerequisite to tailored therapeutic approaches. Biomarkers could be great utility in this setting.We sought evaluate the combined assessment Galectin 3 (Gal-3) binding protein (Gal-3bp) for post-AMI large, consecutive population AMI patients. The primary outcomes were: Recurrent angina/AMI all-cause mortality 12 months after index event.In total, 469 patients were included....
Survivors after a myocardial infarction (MI), especially those with diabetes mellitus (DM), remain at high risk of further events. Identifying and treating factors that may influence survival open new therapeutic strategies. We assessed the impact on prognosis DM hypovitaminosis D (hypovitD), alone or combined. In this prospective, observational study, 1081 patients were enrolled surviving an MI divided into four groups according to their diabetic VitD status. The primary end-point was...
The role of sex in determining the profile and outcomes patients with myocarditis is largely unexplored. We evaluated impact as a modifier factor clinical characterization natural history definite diagnosis myocarditis.We retrospectively analysed single-centre cohort consecutive (i.e. endomyocardial biopsy or cardiac magnetic resonance proven). Specific sub-analyses were performed cohorts chest pain, ventricular arrhythmias, heart failure different main symptoms at presentation. primary...
To evaluate in a real-world primary percutaneous coronary intervention (pPCI) registry the impact of evolution evidence-based treatments on prognosis.STEMI patients undergoing pPCI at University Hospital Trieste, Italy, were enrolled. The first cohort (old cohort) included STEMI treated between January-2007 and December-2012, second (new cohort), January-2013 December-2020. Inverse Probability Treatment Weighting (IPTW) Cox regression models as well multivariable performed to assess risk...
Abstract A dyssynchronous biventricular activation, which can be determined by left bundle branch block, chronic right ventricular pacing, frequent premature complexes, or pre-excitation, cause a global abnormal contractility, thus leading to systolic dysfunction and remodelling in unique nosological entities: conduction-induced cardiomyopathies. In this clinical scenario, the mainstay therapy is eliminating improving LV dyssynchrony, removing trigger. This usually ensures improvement even...
There is increasing evidence of cardiac involvement in COVID-19 cases, with a broad range clinical manifestations spanning from acute life-threatening conditions such as ventricular dysrhythmias, myocarditis, myocardial ischemia and pulmonary thromboembolism to long-term cardiovascular sequelae. In particular, myocarditis represents an uncommon but frightening complication SARS-CoV-2 infection. Even if many reports SARS CoV-2 are present the literature, majority them lacks histological...