A5090500828- Plant Pathogens and Fungal Diseases
- Fungal Plant Pathogen Control
- Plant Physiology and Cultivation Studies
- Postharvest Quality and Shelf Life Management
- Plant Disease Management Techniques
- Plant Gene Expression Analysis
- Mycotoxins in Agriculture and Food
- Endoplasmic Reticulum Stress and Disease
- Mitochondrial Function and Pathology
- Plant-Microbe Interactions and Immunity
- Genetic Neurodegenerative Diseases
- Plant Molecular Biology Research
- Genomics, phytochemicals, and oxidative stress
- Sirtuins and Resveratrol in Medicine
- Plant Stress Responses and Tolerance
- Protein Degradation and Inhibitors
- Garlic and Onion Studies
- Histone Deacetylase Inhibitors Research
- Plant biochemistry and biosynthesis
- Plant Reproductive Biology
- Glioma Diagnosis and Treatment
- Heat shock proteins research
- Fungal Biology and Applications
- Redox biology and oxidative stress
- Essential Oils and Antimicrobial Activity
Institute of Agrifood Research and Technology
2017-2024
Universitat de Lleida
2012-2019
Biomedical Research Institute of Lleida
2012-2019
Glioblastoma multiforme is resistant to conventional anti-tumoral treatments due its infiltrative nature and capability of relapse; therefore, research efforts focus on characterizing gliomagenesis identifying molecular targets useful therapy. New therapeutic strategies are being tested in patients, such as Histone deacetylase inhibitors (HDACi) either alone or combination with other therapies. Here two HDACi included clinical trials have been tested, suberanilohydroxamic acid (SAHA)...
Infections by the fungus Monilinia laxa, main cause of brown rot in Europe, result considerable losses stone fruit. Herein, we present a comprehensive transcriptomic approach to unravel strategies deployed nectarine fruit and M. laxa during their interaction. We used laxa-inoculated immature mature fruit, which was resistant susceptible rot, respectively, perform dual RNA-Seq analysis. In host responses, pathogen biomass, transcriptional activity peaked at 14-24 h post inoculation (hpi),...
Yeast Sir2 is an NAD-dependent histone deacetylase related to oxidative stress and aging. In a previous study, we showed that regulated by S-glutathionylation of key cysteine residues located at the catalytic domain. Mutation these results in strains with increased resistance disulfide stress. present mutant cells were highly resistant acetic acid had chronological life span. Mutant acetyl-CoA synthetase activity, which converts generated yeast metabolism acetyl.CoA. This could explain lower...
Volatile organic compounds (VOCs) are responsible for the antagonistic activity exerted by different biological control agents (BCAs). In this study, VOCs produced Pseudomonas synxantha strain 117-2b were tested against two kiwifruit fungal postharvest pathogens: Cadophora luteo-olivacea and Botrytis cinerea , through in vitro vivo assays. results demonstrated that P. inhibit mycelial growth of C. B. 56% 42.8% after 14 5 days exposition, respectively. assay significant inhibitory effects....
Monilinia is the causal agent of brown rot in stone fruit. The three main species that cause this disease are laxa, M. fructicola, and fructigena, their infection capacity influenced by environmental factors (i.e., light, temperature, humidity). To tolerate stressful conditions, fungi can produce secondary metabolites. Particularly, melanin-like pigments contribute to survival unfavorable conditions. In many fungi, pigment due accumulation 1,8-dihydroxynaphthalene melanin (DHN). study, we...
The secretion of cell wall‐degrading enzymes is one the mechanisms used by necrotrophic fungi to colonize host tissues. However, information about virulence factors Monilinia spp., causal agents brown rot in stone fruit, scarce. Plant walls have three main components that are broken down fungal enzymes: cellulose, hemicellulose and pectin. In order identify laxa candidate proteins involved pectin hydrolysis, two vitro approaches were conducted: (i) phenotypic ecophysiological...
In the present work, major physiological and compositional changes occurring during ‘Merrill O’Henry’ peach growth its relationship with susceptibility to three strains of Monilinia spp. at 49, 77, 126 160 days after full bloom were explored. Results disease incidence indicated wide differences among phenological stages, being 49 moment when peaches showed significantly lower brown rot (40 23% rotten fruit, respectively, for strain ML8L). Variation in different stages was also...
The development of brown rot caused by the necrotrophic fungi Monilinia spp. in stone fruit under field and postharvest conditions depends, among others, on environmental factors. effect temperature humidity are well studied but there is little information role light disease development. Herein, we two lighting treatments a control condition (darkness) on: (i) several growth parameters ( M. laxa fructicola ) grown vitro (ii) their capacity to (nectarines) when exposed different treatments....
Pathogenic fungi are influenced by many biotic and abiotic factors. Among them, light is a source of information for also stress factor that triggers multiple biological responses, including the activation secondary metabolites, such as production melanin pigments. In this study, we analyzed melanin-like in vitro conditions, well expression all biosynthetic regulatory genes DHN-melanin pathway three main Monilinia species upon exposure to conditions (white, black, blue, red, far-red...
Abiotic factors such as light influence the physicochemical properties of fruit and may alter response to environment. The aim this study was investigate effect two postharvest storage conditions on overall quality natural fungal disease incidence (fruit decay) organic nectarines. Experiments were conducted with four organically grown nectarine cultivars (two early-mid season late-season) that unbagged or bagged during preharvest. After harvest, they stored for 7–9 days in darkness under a...