A5077695310- Bacteriophages and microbial interactions
- Antimicrobial Resistance in Staphylococcus
- Microbial Metabolism and Applications
- Bacterial biofilms and quorum sensing
- Enterobacteriaceae and Cronobacter Research
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Bacillus and Francisella bacterial research
- Antibiotic Resistance in Bacteria
- Cancer Research and Treatments
- Hemiptera Insect Studies
- Insect Utilization and Effects
- Identification and Quantification in Food
- Peptidase Inhibition and Analysis
- Ubiquitin and proteasome pathways
- Enzyme Production and Characterization
- Bacterial Genetics and Biotechnology
- Antimicrobial Peptides and Activities
- Insects and Parasite Interactions
- Animal Genetics and Reproduction
- Poxvirus research and outbreaks
- Yersinia bacterium, plague, ectoparasites research
- Language, Communication, and Linguistic Studies
- Clostridium difficile and Clostridium perfringens research
- Nuclear Structure and Function
State Research Center for Applied Microbiology and Biotechnology
2012-2024
University of Southern California
1997-1998
The antibacterial resistance and virulence genotypes phenotypes of 148 non-duplicate Klebsiella pneumoniae strains collected from 112 patients in Moscow hospitals 2012-2016 including isolates the respiratory system (57%), urine (30%), wounds (5%), cerebrospinal fluid (4%), blood (3%), rectal swab (1%) were determined. majority (98%) multidrug resistant (MDR) carrying blaSHV (91%), blaCTX-M (74%), blaTEM (51%), blaOXA (38%), blaNDM beta-lactamase genes, class 1 integrons porin protein gene...
Increases in the prevalence of antibiotic-resistant strains Staphylococcus aureus have elicited efforts to develop novel antimicrobials treat these drug-resistant pathogens. One potential treatment repurposes lytic enzymes produced by bacteriophages as antimicrobials. The phage Twort endolysin (PlyTW) harbors three domains, a cysteine, histidine-dependent amidohydrolases/peptidase domain (CHAP), an amidase-2 and SH3b-5 cell wall binding (CBD). Our results indicate that CHAP alone is...
Staphylococcus aureus clonal complex 8 (CC8) has not been associated with staphylococcal scalded-skin syndrome (SSSS) in newborns and exfoliative toxin genes. Here, we report the draft genome sequences of A-producing B-7772, B-7777 (both CC8), B-7774 (CC15) strains SSSS newborns.
Staphylococcus aureus is one of the most important human pathogens and causes over 100 nosologicalforms diseases. The lack data on spread S. genetic types specific for different forms staphylococcal infections in Russia makes it difficult to timely identify control strains this epidemiologically dangerous bacterial pathogen.The aim study was carry out a molecular research isolates obtained during widespread foodborne illness outbreak among builders at Pulkovo airport St. Petersburg 2013.The...
F. tularensis strain 15/23-1 recA is different from the vaccine line 15 NIIEG by lacking one two copies of iglC gene and has reduced its reactogenicity for experimental animals (BALB/c mice guinea pigs): transient weight reduction less expressed, as well leukopenia thrombocytopenia during first week after immunization, compared to strain. The concentration gamma-interferon in blood serum 7 days immunized with recA, was 5 times than NIIEG. virulence modified more orders magnitude. According...
Background: Endogenous antimicrobial peptides (AMPs) are evolutionarily ancient molecular factors of innate immunity that play a key role in host defense. The study the diversity animal defense has important applications context growing global resistance. Methods: In this using transcriptome mining approach, we found three novel thanatin-like β-hairpin AMPs bean bug Riptortus pedestris, named Rip-2, Rip-3, and Rip-4. were expressed bacterial system, their activities evaluated both vitro...
Staphylococcus aureus clonal complex (СС) 30 are associated with hospital-acquired and community-associated invasive infections may cause outbreaks of staphylococcal food-borne (SFI). In recent years, severe SFI caused by S. CC30 in cohorts not linked to high-risk groups have been detected Russia.Aim: The aim the study is conduct a comparative genomic analysis strains B-7778 B-7779 isolated during widespread outbreak at International Youth Forum Seliger 2014, B-7738 B-7739 among construction...
Clinical strains of Staphylococcus aureus were tested for hemolytic activity on blood agar, in the PCR test and by analyzing gene alleles toxins. The study analyzed information content phenotypic determination to assess pathogenic properties S. isolates.
We report here the draft genome sequences of eight Staphylococcus aureus strains isolated during three large food poisoning outbreaks in Russian Federation. The were collected from clinical specimens and various foodstuff samples.