A5017398040- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Synthesis of Organic Compounds
- Synthesis of heterocyclic compounds
- Crystallization and Solubility Studies
- Quinazolinone synthesis and applications
- Synthesis and Reactions of Organic Compounds
- X-ray Diffraction in Crystallography
- Organophosphorus compounds synthesis
- Sulfur-Based Synthesis Techniques
- Synthesis and Catalytic Reactions
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Phenothiazines and Benzothiazines Synthesis and Activities
- Organic Chemistry Cycloaddition Reactions
- Crystallography and molecular interactions
- Synthesis and Biological Evaluation
- Analytical Chemistry and Chromatography
- Chemical Reaction Mechanisms
- Chemical Reactions and Mechanisms
- Chemical Synthesis and Reactions
- Synthetic Organic Chemistry Methods
- Biochemical Analysis and Sensing Techniques
- Polyoxometalates: Synthesis and Applications
- Click Chemistry and Applications
National Research Centre
1984-2019
National Water Research Center
1998-2019
National Research Institute
1998
Abstract Condensation of 5,6-dimethyl-2-hydrazino-3,4-dihydrothieno[2,3-d]pyrimidin-4-one (2) with aromatic aldehydes gave the arylhydrazones 3a-c which cyclized into thienotriazolopyrimidin-5- one 4a-c. Reactions 2 aliphatic acids afforded thienotriazolopyrimidin-5-one 5a.b. Also, reaction each carbon disulfide and nitrous acid 3-mercaptothienotriazolopyrimidin-5-one 7, tetrazolothienopyrimidin-5-one 8, respectively, latter compound 8 could be reduced to 2-aminothienopyrimidin-4-one 9. On...
AbstractA series of 3″,5″-diaryl-3″H-dispiropyran/thiopyran[4,2′-chroman-3′,2″-[1,3,4-thiadiazol]-4′-ones 5a-n were synthesized from the reaction trispiro[tetrahydropyran(tetrahydrothiopyran)-4,5′-2H-chromeno-[3,4-e][1,3,4]oxadithiin-2′,3″-chroman-2″4′″-tetrahydropyran-(tetrahydrothiopyran)]-4″-ones 3a,b with nitrilimines (generated in situ via triethylamine dehydrohalogenation corresponding hydrazonoyl chlorides). A single crystal diffraction compound 5a adds support for established...
Abstract In a one-pot synthesis 6,7-dimethyl-2-arylidine-5-H-thieno[2,3-d]pyrimidine-3,5-diones 2 were prepared via the reaction of ternary mixture 5,6-dimethyl-2-thioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-4-one (1), chloroacetic acid, and proper aldehyde. Compound reacted with hydroxylamine to afford 2,3-dihydro-7,8-dimethyl-3-substituted-9H-isoxazolo[5′,4′:4,5]thiazolo [3,2-a] thieno[2,3-d]pyrimidin-9-ones (4). Reaction 1 3-chloropent-2,4-dione in ethanolic potassium hydroxide yielded...
2-(4-Fluorophenyl)methylidene-1-thiooxoindane-, 2-(4-methoxyphenyl) methylidene-1-thiooxoindane-, 2-(4-N,N-dimethyaminophenyl)methylidene-1-thiooxoindane dimers 5a–c were prepared by the reaction of corresponding α,β -unsaturated ketones 3a–c with Lawesson' Reagent (LR) in refluxing benzene. When these refluxed LR xylene, 1,2-thiaphospholene-2-sulfides 7a–c obtained. On other hand, thermolysis presence acrylamide or dichloromaleic anhydride gave cycloadducts Diels-Alder type 8a–c, and 10a–c,...
Abstract 2‐Amino‐and 2‐hydrazino‐5‐(3 or 4‐pyridyl)‐1, 3, 4‐oxadiazoles [II i‐k ] have been prepared by racting 2‐chloro derivatives with the corresponding amines hydrazines, 2‐hydrazino (II ) compounds that obtained were heated carbon disulphide and alcoholic potassium hydroxide where 5‐(3 4‐pyridyl)‐1,3,4‐oxadiazolo (2,3‐C)‐1,2,4‐triazole 5‐thione (III a‐c obtained, given structures biologically screened.
Abstract Trans, 10,11-dibromide Ic reacted with di- and triethyl phosphites to yield 5-hydroxy, 5-phosphonate II, while 5-oximes IIIa‒d gave 5-hydroxylamino-5-phosphonates IVa-d . I c Na2S give 10,11-sulphide V that hydrogen peroxide the sulphone VI ethyl cyanoac-etate VII. Key Words: Trans-10,11-dibrorao-10,11-dihydrodibenzo[a,d]-cyclohepten-5-hydroxy5-phosphonate II10,11-dihydro-10-bromo-10,11-dibromo-10,11 dihydrodibenzo-or dibenzo[a,d]-cyclohepten-5-hydroxylamino,5-phosphonate IV...
Some new 3′,5′-substituted-5H,3′ H-spirodibenzo[a, d]cycloheptene-5,2′-[1,3,4]thiadiazole and 10,11-dihydro-5H,3′ derivatives 3a–n were regioselectively synthesized under 1,3-dipolar cycloaddition of 5-thiooxo-5H-dibenzo[a, d]cyclo-heptene 5-thiooxo-10,11-dihydro-5H-dibenzo[a, d]cycloheptene with a variety nitrilimines (generated in situ via dehydrohalogenation the corresponding hydrazonoyl chlorides presence triethylamine). The products tested for antiinflammatory, analgesic, ulcerogenic...
Abstract 2-Aryl-1-oxaspiro(2,5)octa-4-ones Ia,b were synthesized and reacted with thiourea in ethanol to give hydroxy cyclohexanone derivatives IIa,b. Compounds IIa,b readily cyclised into the corresponding 5-hydroxy quinazolines IIIa,b their dehydrated IVa,b. A mixture of compounds III IV also prepared directly from reaction alkaline medium. Va,b produced by reduction IV. or V chloroacetic acid resp. VI VII, which condensed aromatic aldehydes form VIII IX.
The chlorination of 5-thioxo-10,11-dihydro-5 H -dibenzo[ a,d ]cycloheptene 2a gave 5-chloro-10,11-dihydro-5 ]cycloheptene-5,10-sulfide 4 . Chlorination 5-thioxo-5 2b the two isomers cis - and trans -5,11-dichloro-10,11-dihydro-5 7a,b sulfides were oxidized by using mCPBA or 2 O /AcOH to give corresponding sulfoxides 5 8a,b , respectively. Treatment sulfide with KI primary ketone 1b together -5-chloro-11-hydroxy-10,11-dihydro-5 9 structures new compounds established different spectroscopic...
Abstract 2-Aryl-1-oxaspiro(2,5)octa-4-ones Ia,b reacted with carbon-disulfide, phenylisocyanate, or phosphorus pentasulfide to yield compounds II, III, IV respectively. The bis-spirodioxane V is produced when compound Ib was heated at 150 °c for 1 hr. Key Words: Oxaspire(2,5) octanesOxathiospirodecanesBenzoxazinestetrahydrobon-zodithiols
Abstract The preparation of some 3,5‐diarylidene‐1‐thipyran‐4‐one derivatives (Ia‐e) was described. Oxidation Ia, b and Ie with hydrogen peroxide gave the corresponding dioxides (IIa‐c). Reaction 1‐thiapyran‐4‐one bromine, Grignard reagents, amines were studied. Structural assignments are supported by spectral (UV, IR, 1 HNMR) data.
Abstract Die heteroaromatischen Thiole (Ia)‐(Id) werden mit Chloressigsäureester (II) und anschließend Hydrazin in die Hydrazide (IHa) bis (IIId) übergeführt.
Abstract Reaktion der Thioxanthone (I) mit Cu‐Bronze/Diazoessigester (II) und nachfolgende Verseifung liefern die Säure (IIIa) bzw. (IIIb); (IV) wird analog gewonnen.
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”
Abstract Die Thiochromone (Ic), aus den Sauerstoffanalogen (Ia) mit P4810 oder dem Thiochromen (II) Benzaldehyden (III) (bessere Ausb.) synthetisiert, reagieren Diphenyldiazomethan zu Chromenen (Id).