Madhavi Mangalarapu

ORCID: 0000-0002-7086-124X
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About
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Research Areas
  • Curcumin's Biomedical Applications
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Scientific Research and Studies
  • Pharmacological Effects and Assays
  • RNA modifications and cancer
  • Advanced Glycation End Products research
  • Therapeutic Uses of Natural Elements
  • Retinal Diseases and Treatments
  • Asthma and respiratory diseases
  • Natural Antidiabetic Agents Studies
  • Phytochemical and Pharmacological Studies
  • Cancer-related molecular mechanisms research
  • Oral Health Pathology and Treatment

Osmania University
2016-2024

Advanced Glycation End products (AGEs) interaction with Receptor for AGEs (RAGE) activates downstream signaling and evokes inflammatory responses in vascular cells. Therefore, it is of interest to design a novel series molecules library 352 compounds based on natural Isoflavone Argpyrimidine moities. The screened against the optimized structure RAGE (PDB code: 3CJJ) using MolDock aided molecular docking algorithm. This exercise identified compound number 62 appreciable ADME properties having...

10.6026/97320630012124 article EN cc-by Bioinformation 2016-06-15

Medicinal plants have been used since ancient times to prepare medicines in the form of extracts. Alcoholic and aqueous extracts various parts medicinal may contain potentially useful chemical compounds with biological activity. Therefore, some are still obtain effective even potent medicines. It is believed that can a protective effect on kidneys their diseases. However, existing information renal-tropic drugs obtained from plant raw materials activity does not allow us draw unambiguous...

10.17816/rcf635346 article EN Reviews on Clinical Pharmacology and Drug Therapy 2024-12-15

Epidemiological evidence indicates that plant derived flavonoids and other phenolic antioxidants can be used to treat cancers. Curcumin is one such flavonoid considerably more effective than antioxidants; it a potent drug against many diseases cancer.

10.38124/ijisrt20may607 article EN International Journal of Innovative Science and Research Technology (IJISRT) 2020-06-17
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