- Complex Systems and Decision Making
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Gene expression and cancer classification
- Climate Change and Health Impacts
- Lung Cancer Treatments and Mutations
- Hepatocellular Carcinoma Treatment and Prognosis
- Helicobacter pylori-related gastroenterology studies
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical site infection prevention
- Thyroid and Parathyroid Surgery
- Ion Transport and Channel Regulation
- Bioinformatics and Genomic Networks
- Cognitive Science and Mapping
- Liver Disease Diagnosis and Treatment
- Orthopaedic implants and arthroplasty
- Ultrasound and Hyperthermia Applications
- Air Quality and Health Impacts
- Thermal Regulation in Medicine
- Cardiac and Coronary Surgery Techniques
- Evaluation and Performance Assessment
- Mechanical Circulatory Support Devices
- Cancer Diagnosis and Treatment
- Surgical Sutures and Adhesives
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
EVERSANA (Canada)
2020-2024
New Zealand Association of Counsellors
2023
St Vincent's Hospital
2017-2018
University of Strathclyde
2016-2017
Population Health Research Institute
2012-2014
McMaster University
2012-2014
Digestive Health Research Institute
2014
Durham University
2011
University of Toronto
2010
University of Wisconsin–Superior
2006
GeneMANIA (http://www.genemania.org) is a flexible, user-friendly web interface for generating hypotheses about gene function, analyzing lists and prioritizing genes functional assays. Given query list, extends the list with functionally similar that it identifies using available genomics proteomics data. also reports weights indicate predictive value of each selected data set query. Six organisms are currently supported (Arabidopsis thaliana, Caenorhabditis elegans, Drosophila melanogaster,...
Microarray techniques provide a valuable way of characterizing the molecular nature disease. Unfortunately expense and limited specimen availability often lead to studies with small sample sizes. This makes accurate estimation variability difficult, since variance estimates made on gene by basis will have few degrees freedom, assumption that all genes share equal is unlikely be true.We propose model which within variances are drawn from an inverse gamma distribution, whose parameters...
Abstract Summary: The GeneMANIA Cytoscape plugin brings fast gene function prediction capabilities to the desktop. identifies most related genes a query set using guilt-by-association approach. uses over 800 networks from six organisms and each is traceable source network used make prediction. Users may add their own interaction expression profile data complement or override default data. Availability Implementation: implemented in Java freely available at http://www.genemania.org/plugin/....
To investigate the response to inhaled prostacyclin in patients with primary and secondary pulmonary hypertension compare its effects those of intravenous nitric oxide. Twelve (seven five secondary) were studied. All had a artery balloon flotation catheter inserted into proximal radial arterial line. Prostacyclin was nebulized 81. min−1 oxygen administered doses increasing from 15 50 ng. kg−1. via facemask. Eight these also received 1 5 ng.kg−1.min−1 oxide 10 100 ppm Haemodynamic...
Summary The Somanetics Invos 3100 cerebral oximeter is a new noninvasive device which measures the regional oxygen saturation of haemoglobin within microvasculature by infrared spectroscopy. It was used in nine patients undergoing elective cardiac surgery and its results were compared with measurements jugular venous bulb saturations obtained Oximetrix Opticath oximetry system. index value analysis blood an 11282 cooximeter. less accurate precise (standard deviation difference 14.1%) than...
Colorectal surgical procedures place substantial burden on health care systems because of the high complication risk, site infections in particular. The risk infection after colorectal surgery is one highest any specialty.The purpose this study was to determine incidence, cost surgery, and potential economic benefit using antimicrobial wound closure improve patient outcomes.Retrospective observational cohort analysis probabilistic were performed.The utilized a database for patients United...
BackgroundStandard treatment for early-stage or locoregionally advanced non-small cell lung cancer (NSCLC) includes surgical resection. Recurrence after surgery is commonly reported, but a summary estimate postsurgical recurrence-free survival (RFS) in patients with NSCLC lacking.Research QuestionWhat the RFS stage I-III at different time points, and what factors are associated RFS?Study Design MethodsA systematic search was performed MEDLINE, EMBASE, Cochrane databases between January 2011...
Comparison of Pulmonary Function and Other Parameters in Two Communities with Widely Different Air Pollution Levels Richard A. Prindle, Deputy ChiefM.D.M.P.H.F.A.P.H.A., Samuel C. Marcus, Assistant Chief (Biometry Section), George W. Wright, HeadM.D., Thomas LloydM.D., Roy O. McCaldin, ChiefPh.D.F.A.P.H.A., Willis E. Bye CopyRight https://doi.org/10.2105/AJPH.53.2.200 Published Online: August 29, 2011
Abstract Background Interstitial cells of Cajal associated with the submuscular plexus ( ICC ‐ SMP ) generate omnipresent slow‐wave activity in colon and are prominent motor patterns. Our aim was to investigate dysfunction W/W v mice which reportedly reduced. Methods Whole organ motility studied using spatio‐temporal mapping; immunohistochemical staining carried out for c‐Kit Ano1; calcium imaging applied . Key Results Discrepancies between Ano1 were found both wild‐type colon. reduced ~50%...