A5014070584- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Long-Term Effects of COVID-19
- Mosquito-borne diseases and control
- COVID-19 Clinical Research Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Chronic Lymphocytic Leukemia Research
- Inflammatory Myopathies and Dermatomyositis
- Dermatological and COVID-19 studies
- Viral Infections and Vectors
- Systemic Sclerosis and Related Diseases
- COVID-19 and Mental Health
- Vascular anomalies and interventions
- Biosimilars and Bioanalytical Methods
- Hematological disorders and diagnostics
- Liver Diseases and Immunity
- Urticaria and Related Conditions
- Dental Radiography and Imaging
- Vasculitis and related conditions
- Eosinophilic Disorders and Syndromes
- Leprosy Research and Treatment
- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Galectins and Cancer Biology
Instituto de Medicina Integral Professor Fernando Figueira
2018-2025
Sociedade Brasileira de Ortopedia e Traumatologia
2023
Hospital das Clínicas da Universidade Federal de Pernambuco
2019-2023
Integra (United States)
2019
Universidade Federal de Pernambuco
2013
OBJECTIVES:Hydroxychloroquine is an antimalarial agent that has been used in systemic lupus erythematosus and rheumatoid arthritis treatment for many years.Recently, novel mechanisms of action have proposed, thereby broadening the therapeutic perspective this medication.The purpose study was to evaluate immunomodulatory activity hydroxychloroquine T helper 17 (Th17) cytokines healthy individuals patients.METHODS: Eighteen female patients with (mean age 39.0¡12.9years) 13 51.5¡7.7 years) were...
Abstract Objectives To compare the impact of COVID-19 on clinical status and psychological distress patients with immune-mediated rheumatic disease (IMRD) caused by SARS-CoV-2 infection that noninfected IMRD controls during a 6-month follow-up period. Methods The ReumaCoV Brazil is longitudinal study designed to follow for 6 months after (patients) compared without (controls). Clinical data, activity measurements current treatments regarding outcomes were evaluated in all patients. Disease...
Este estudo tem como objetivo revisar o manejo da úlcera gástrica, abordando diagnóstico, terapêutica clínica e intervenções cirúrgicas, com ênfase nas diretrizes mais recentes de atualizações científicas. A gástrica resulta do desequilíbrio entre fatores agressores protetores mucosa gastrointestinal, destaque para a infecção por Helicobacter pylori uso anti-inflamatórios não esteroidais (AINEs). Entre as complicações, destacam-se hemorragia digestiva alta perfuração, sendo uma das causas...
Background . Due to the variety of functions that galectins (Gal) possess, it is clear they participate in pathogenesis rheumatoid arthritis (RA). Although some studies demonstrate their functions, there still no correlation with clinical data disease, having physiological meaning unknown. Objectives To compare serum levels Gal-1, -4, and -7 patients RA healthy controls correlate them parameters. Methods Serum samples were collected from donors determine -7. Results significantly higher...
<h3>Background</h3> Chikungunya Fever (CHIK) may evolve chronically with joint impairment, often disabling, which leads to a functional and quality of life impact. The CHIK outbreak in Brazil began 2015, reaching its peak 2016, particularly the Northeast country, 2 35 136 reported cases. Since this is first epidemic Brazil, data on persistent post-acute disease are scarce, knowledge fundamental importance defining long-term impact disease. <h3>Objectives</h3> To evaluate factors associated...
Abstract Objectives To compare the impact of COVID-19 on clinical status and psychological condition in patients with immune-mediated rheumatic diseases (IMRD) infected by SARS-CoV-2 IMRD controls not infected, during a 6-month follow-up. Methods The ReumaCoV Brasil is longitudinal study designed to follow-up for 6 months after (cases) compared no (controls). Clinical data, disease activity measurements current treatment regarding IMRD, outcomes were evaluated all patients. Disease was...
<title>Abstract</title> Objectives To compare the impact of COVID-19 on clinical status and psychological distress patients with immune-mediated rheumatic disease (IMRD) caused by SARS-CoV-2 infection that noninfected IMRD controls during a 6-month follow-up period. Methods The ReumaCoV Brazil is longitudinal study designed to follow for 6 months after (patients) compared without (controls). Clinical data, activity measurements current treatments regarding outcomes were evaluated in all...
O Sistema Único de Saúde (SUS) utiliza três modalidades atenção: Baixa complexidade, média complexidade e alta complexidade. Sendo a Atenção Primária à (APS) que disponibiliza entrada no sistema saúde para problemas necessidades dos sujeitos. Sobre terapia anticoagulante/antiplaquetária, tem como objetivo um efeito preventivo, reduzindo os riscos acidente vascular cerebral, porém, estes elevam possibilidade hemorragia durante procedimentos odontológicos mais invasivos. Este trabalho trata-se...
The management of localized gastric cancer has evolved considerably with the advent novel perioperative treatment strategies chemotherapy, significantly impacting patient outcomes. Traditionally, surgery been cornerstone treatment, but recurrence rates remained high, necessitating exploration additional therapies to enhance long-term survival. interplay between chemotherapy and radiotherapy is being meticulously studied define optimal sequencing combination that maximizes tumor control while...
Introdução: Pacientes com doenças como lúpus eritematoso sistêmico (LES) e artrite reumatoide (AR) são especialmente predispostos a desenvolver sarcopenia à luz do estado pró-inflamatório subjacente da diminuição uso muscular devido inatividade dor. Objetivo: Verificar correlação risco de o nutricional em portadores assistidos um centro referência no Nordeste. Metodologia: Estudo transversal 114 pacientes idade entre 18 85 anos. Foram coletadas informações clínicas dados antropométricos...
<h3>Background</h3> Antimalarials (AM) have been related to a lower risk and severity of infections in systemic lupus erythematosus [1], but rheumatoid arthritis (RA) the results are not unanimously favorable possible protective effect exerted by AM [2,3]. In our recent study RA patients treated with biologic disease modifying anti-rheumatic drugs (bDMARDs) or JAK inhibitors (JAKi), secondary analysis suggested total (25% reduction) serious (47% concomitant use [4]. <h3>Objectives</h3> To...
<h3>Background</h3> The COVID-19 pandemic has brought uncertainties to rheumatology practice, mainly related the possibility of triggering disease activity after infection in immune mediated rheumatic diseases (IMRD). To date, there are few data literature specifically evaluating this issue. <h3>Objectives</h3> Evaluate IMRD patients 6 months infection, compared pre status. <h3>Methods</h3> ReumaCoV Brasil is a longitudinal study performed at 35 centers designed follow-up for clinical or...
<h3>Background</h3> Golimumab and certolizumab were the last original anti-TNF agents approved in Brazil for treatment rheumatoid arthritis (RA). Recent studies indicate that is associated with higher risk of infections [1] golimumab better drug survival compared to other [2], although they have not been head-to-head trials. <h3>Objectives</h3> To evaluate adverse effects course RA patients treated or golimumab. <h3>Methods</h3> BiobadaBrasil a multicentric registry-based cohort study...
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that associated with impairment of the quality life. Neuropsychiatric disorders are common clinical manifestations SLE, such as anxiety. This study aimed to determine prevalence anxiety and association between parameters SLE.
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that occurs intermittently with periods of exacerbation and remission. Neuropsychiatric disorders including depression are common clinical manifestations SLE. This study aimed to determine the prevalence evaluate association between parameters
Chikungunya (CF) fever is a viral disease transmitted to humans by the Aedes aegypti mosquito, infected virus (CHIKV), causing disabling musculoskeletal symptoms. Some studies have associated levels of vitamin D with symptoms, although this relationship has not yet been studied in CF. The aim present study was analyze and their possible association debilitating
Chikungunya fever (CF) is an infection caused by arbovirus, associated with and arthritis in the acute phase a progression for chronic 15-60% of patients. Aspartate aminotransferase (AST) alanine (ALT) are cytosolic mitochondrial enzymes abundant liver but also present other tissues their elevation may reflect cellular tissue damage. This study aimed to investigate relationship between these clinical manifestations CF distinct phases disease.
Chikungunya Fever (CF) is a virus infection transmitted by Aedes mosquitoes with multiple osteoarticular symptoms and became epidemic in 2015, especially northeast region. Guidelines from the Brazilian Rheumatology Society include corticosteroids anti-malarial drugs as options for management of disease but scientific evidence to support use these poor. The study aimed analyze CF treatment performed reference hospital Recife, Pernambuco.
Rheumatoid arthritis (RA) is a chronic disease characterized by multiple joint involvement and morbidity. In Brazil, it estimated that 1% of adult population from macroregions has the disease. Jaboatão dos Guararapes second most populous city in state Pernambuco there are no public services within to assist specifically patients with RA. The objective this study report implementation an outpatient rheumatoid clinic secondary health care facility. Also, we aimed describe epidemiological...