- Gastrointestinal Tumor Research and Treatment
- Drug-Induced Adverse Reactions
- Inflammatory Bowel Disease
- Gastric Cancer Management and Outcomes
- Contact Dermatitis and Allergies
- Metastasis and carcinoma case studies
- Clinical Nutrition and Gastroenterology
- Pharmacovigilance and Adverse Drug Reactions
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Pregnancy and Medication Impact
- Autoimmune Bullous Skin Diseases
- Pharmaceutical studies and practices
- Neonatal skin health care
- Neutropenia and Cancer Infections
- Banana Cultivation and Research
- Neurogenetic and Muscular Disorders Research
- COVID-19 diagnosis using AI
- Helicobacter pylori-related gastroenterology studies
- Artificial Intelligence in Healthcare and Education
- Osteomyelitis and Bone Disorders Research
- Primary Care and Health Outcomes
- Hormonal Regulation and Hypertension
- Acute Kidney Injury Research
- Childhood Cancer Survivors' Quality of Life
Centro Hospitalar do Porto
2021-2024
Confraria de Santa Luzia
2021-2022
Universidade do Porto
2010-2022
Hospital de São João
2021-2022
Great Ormond Street Hospital
2021
University College London
2021
Administração Regional de Saúde de Lisboa e Vale do Tejo
2017-2021
Médecins du Monde
2018
Ordem dos Médicos
2016
Centre for Health Technology and Services Research
2010-2015
Early life exposures impact immune system development and therefore the risk of immune-mediated diseases, including inflammatory bowel disease (IBD). We systematically reviewed pre-, peri‑, postnatal up to age five years on subsequent IBD diagnosis.We identified case-control cohort studies reporting association between early environmental factors Crohn's (CD), ulcerative colitis (UC), or overall. Databases were search from their inception until May 24th, 2019 July 14th, 2020. conducted...
Although endoscopic resection for the treatment of gastric superficial neoplastic lesions is an established first-line in Eastern countries, its role has yet to be considered Western guidelines, mostly due a lack long-term studies. The aim this study was describe outcomes mucosal (EMR) and submucosal dissection (ESD) neoplasias Portugal.This single-center, retrospective, cohort between March 2003 April 2013. A total 162 consecutive patients with 195 underwent EMR (n = 54) or ESD 141) were...
Abstract Introduction A family history of inflammatory bowel disease [IBD] is the strongest risk factor for disease. However, some first-degree relatives (FDRs) will develop disease, while others not. Methods Using nationwide Danish National Patient Register, we examined factors in families with two or more affected FDRs. First, compared exposures between siblings and without IBD within same [within-family analysis]. Second, individuals across all [across-family Exposures included sex, birth...
Background and study aims: In Japanese centers, endoscopic submucosal dissection (ESD) is commonly used for the resection of early gastric lesions. However, in Europe, only a few reports have been published. The aim current was to survey use ESD by European endoscopists.
ChatGPT has attracted a lot of interest worldwide for its versatility in range natural language tasks, including the education and evaluation industry. It can automate time- labor-intensive tasks with clear economic efficiency gains.
Endoscopic submucosal dissection (ESD), an endoscopic technique used for treatment of gastric superficial lesions, has been gaining importance on western countries. Procedural times have impact various outcomes. To define which factors from patients, lesions and procedure can predict longer procedural times. In a cohort 127 resected by ESD with IT-knife, after using needle-knife layer access, experienced gastroenterologists, characteristics the patient (age, gender, presence co-morbidities,...
The fruit has become an innovative activity, especially the use of skilled labor and specialized cultivation. This led to replacement traditional crops low profitability per crop whose production is intended mainly for foreign markets, optimized by irrigation technologies increased productivity.This situation been observed in Agropoli implementation / or implemented State Ceará. BaixoAcaraú Irrigation District (DIBAU) covers townsof Bela Cruz Marco directly generating more than three...
The therapeutic approach to inflammatory bowel disease (IBD) is complex, often involving multiple pharmacologic classes. We aimed evaluate the prevalence of drug-related adverse reactions (ARs) associated with therapies used in pediatric IBD. conducted a retrospective study patients IBD followed tertiary hospital from 2010 2022. Ninety-nine were included (62.6% male), median age at diagnosis 13 years (interquartile range [IQR] 11-15 years). majority had Crohn's (69.7%), by ulcerative colitis...
Objective To review the outcome of children with severe neurological impairment (NI) and intestinal failure (IF) referred to our specialist multidisciplinary IF rehabilitation service discuss implications. Design Case report series, descriptive analysis. Setting programme at a tertiary children’s hospital in UK. Patients Children NI from 2009 2019. Main measures Demographic social data, diagnosis, clinical condition, use home parenteral nutrition (HPN), complications, ethics advance care...
In the last years, global context of medical education and Medical Residency programs in Portugal suffered substantial changes. The primary objective this study was to evaluate characterize residents ́ satisfaction with residency identify features that could be improved.We utilized as model survey Postgraduate Hospital Educational Environment Measure has been developed United Kingdom is speci cally targeted residents. translated adapted Portuguese reality. available online during April May...
Introduction: Skin prick tests are important in the evaluation of allergic sensitization. Besides allowing identifying allergens involved, they for implementation environmental eviction measures and therapeutic strategies. Objectives: To identify sensitization profile to aeroallergens children with asthma and/or rhinitis followed an hospital north coast Portugal. Material Methods: A retrospective study was conducted a review clinical processes patients rhinitis, who performed skin from...
Background: We describe a rare case involving paracetamol, commonly used drug worldwide. Increased paracetamol consumption increases the risk of adverse reactions. Case Presentation: This is 9-year-old girl who visited emergency department due to sudden onset sneezing, nasal itching, urticaria, and angioedema after ingestion. The diagnostic etiologic studies revealed an immunoglobulin E (IgE)-mediated hypersensitivity mechanism paracetamol. Conclusion: Few cases this phenomenon have been...
<h3>Introduction</h3> Acute dystonia is characterised by involuntary and sustained muscular contractions, which cause repetitive torsional movements and/or anomalous postures. It usually caused drugs such as neuroleptics antiemetics. Normally, the disorder expressed with oromandibular involvement, axial dystonia, retrocolis or oculogyric crisis. Its symptoms develop within first 72 hours after drug administration. <h3>Case report</h3> A 16 year-old female, no personal relevant history, went...
Arthrogryposis multiplex congenita (AMC) is a heterogeneous condition comprising congenital multiple joint contractures, and it secondary to decreased fetal mobility following environmental/genetic abnormalities. BICD2 pathogenic variants have been associated with autosomal dominant spinal muscular atrophy lower extremity predominance (SMALED2). We report the case of newborn movements ventriculomegaly diagnosed in utero, born severe AMC, bone fractures, hip dislocation, respiratory...
Introduction: Meckel’s diverticulum (MD) is usually asymptomatic but may be associated with severe complications that require awareness. This study aimed to assess the clinical and pathological features of symptomatic MD in children as well accuracy [99mTc]sodium pertechnetate scintigraphy. Methods: We retrospectively reviewed all pediatric patients treated between 2007 2018 at a tertiary center. Records included demographics, presentation, scintigraphy pertechnetate, surgical outcome,...
Introduction: Home parenteral nutrition (PN) was originally developed for children with intestinal failure (IF) and no other major organ failure. However, there are a small number of patients severe neurological impairment(NI) who have been referred to our rehabilitation service. Our aim review the outcome these patients. Methods: To all profound NI service from 2009-2019. Data reviewed included diagnosis, indications PN, associated medical social conditions, outcomes, ethical reviews end...
HIDDEN DIAGNOSIS BEHIND A LIMPLimp is a common complaint in childhood, and it defined as an uneven, jerky, or laborious gait, usually caused by pain, weakness deformity.A careful history physical examination enough to determine the cause of limp, but radiographic studies often are necessary confirm clinical suspicions.Although majority has benign cause, significant proportion children can have life-threatening conditions.
improvement-training-in-immunotherapyfor-healthcare-professionals-does-training-make-a-difference