A5031380903- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Advanced Radiotherapy Techniques
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- MRI in cancer diagnosis
- Glioma Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- Radiation Therapy and Dosimetry
- Radiopharmaceutical Chemistry and Applications
University Hospital of Zurich
2022-2024
University of Zurich
2022-2024
University Hospital of Bern
2023
University of Bern
2023
Background and purposeMagnetic resonance imaging (MRI) scans are highly sensitive to acquisition reconstruction parameters which affect feature stability model generalizability in radiomic research. This work aims investigate the effect of image pre-processing harmonization methods on brain MRI features prediction performance models patients with metastases (BMs).Materials methodsTwo T1 contrast enhanced data-sets were used this study. The first contained 25 BMs at two different time points...
The superior tissue contrast of magnetic resonance (MR) compared to computed tomography (CT) led an increasing interest towards MR-only radiotherapy. For the latter, dose calculation should be performed on a synthetic CT (sCT). Patient-specific quality assurance (PSQA) methods have not been established yet and this study aimed assess several software-based solutions.A retrospective was 20 patients treated at MR-Linac, which were selected evenly cover four subcategories: (i) standard, (ii)...
The requirement of computed tomography (CT) for radiotherapy planning may be bypassed by synthetic CT (sCT) generated from magnetic resonance (MR), which has recently led to the clinical introduction MR-only specific sites. Further developments are required abdominal sCT, mostly due presence mobile air pockets affecting dose calculation. In this study we aimed overcome limitation sCT at a low field (0.35 T) hybrid MR-Linac.A retrospective analysis was conducted enrolling 168 patients...
To improve organ at risk (OAR) sparing, dynamic trajectory radiotherapy (DTRT) extends VMAT by table and collimator rotation during beam-on. However, comprehensive investigations regarding the impact of gantry-table (GT) gradient on DTRT plan quality have not been conducted.To investigate a user-defined GT plans in terms dosimetric quality, robustness, deliverability, delivery time.The trajectories are described gantry-collimator paths. The path is determined minimizing overlap OARs with...
Purpose: Magnetic resonance imaging (MRI) scans are highly sensitive to acquisition and reconstruction parameters which affect feature stability model generalizability in radiomic research. This work aims investigate the effect of image pre-processing harmonization methods on brain MRI features prediction performance models patients with metastases (BMs).Methods: Twenty-five BMs contrast enhanced T1-weighted at two different time points were included this test-retest study. The combined gray...
Background and PurposeThe feasibility of acquiring diffusion-weighted imaging (DWI) images on an MR-Linac for quantitative response assessment during radiotherapy was explored. DWI data obtained with a Spin Echo Planar Imaging sequence adapted 0.35 T were examined compared from conventional 3 scanner.Materials MethodsApparent diffusion coefficient (ADC) measurements distortion correction technique investigated using DWI-calibrated phantoms in the brains seven volunteers. All utilized two...