A5043556004- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Dental Radiography and Imaging
- Functional Brain Connectivity Studies
- Ophthalmology and Eye Disorders
- MRI in cancer diagnosis
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Vestibular and auditory disorders
- Fetal and Pediatric Neurological Disorders
- Glioma Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Radiation Dose and Imaging
- Peripheral Nerve Disorders
- Intracranial Aneurysms: Treatment and Complications
- Action Observation and Synchronization
- Motor Control and Adaptation
- Eating Disorders and Behaviors
- Oral and Maxillofacial Pathology
- Medical Image Segmentation Techniques
- Dental Implant Techniques and Outcomes
University Hospital of Zurich
2016-2025
Center for Pediatric Endocrinology Zurich
2025
University of Zurich
2014-2024
Siemens (Switzerland)
2024
ETH Zurich
2007-2021
Resonance Research (United States)
2017
Mayo Clinic
2017
Siemens (Germany)
2015
Laboratory for Social and Neural Systems Research
2011-2013
Institute for Biomedical Engineering
2006-2011
The performance of solid-state dye-sensitized solar cells based on spiro-MeOTAD was considerably improved by controlling charge recombination across the interface heterojunction. This achieved blending hole conductor matrix with a combination 4-tert-butylpyridine (tBP) and Li[CF3SO2]2N. Open circuit voltages Uoc over 900 mV short currents Isc up to 5.1 mA were obtained, yielding an overall efficiency 2.56% at AM1.5 illumination. These values have been fully confirmed National Renewable...
Background and Purpose— Increased stroke risk correlates with hemodynamic failure, which can be assessed ( 15 O-)H 2 O positron emission tomography (PET) cerebral blood flow (CBF) measurements. This gold standard technique, however, is not established for routine clinical imaging. Standardized oxygen-level–dependent (BOLD) functional magnetic resonance imaging+CO a noninvasive potentially widely applicable tool to assess whole-brain quantitative cerebrovascular reactivity (CVR). We examined...
Impaired cerebrovascular reactivity (CVR) has been correlated with recurrent ischemic stroke. However, for clinical purposes, most CVR techniques are rather complex, time-consuming, and lack validation quantitative measurements. The recent adaptation of a standardized hypercapnic stimulus in combination blood-oxygenation-level-dependent (BOLD) magnetic resonance imaging signal as surrogate cerebral blood flow offers potential universally comparable assessment. We investigated the association...
Background The optimization of magnetic resonance spectroscopy (MRS) sequences allows improved diagnosis and prognosis neurological psychological disorders. Thus, to assess the test–retest intersequence reliability such MRS in quantifying metabolite concentrations is clinical relevance. Purpose To evaluate three estimate GABA Glx = Glutamine+Glutamate human brain. Study Type Prospective. Subjects Eighteen healthy participants were scanned twice (range: 1 day week between two sessions) with...
Objective. Visual snow (VS) is a distressing, life-impacting condition with persistent visual phenomena. patients show cerebral hypermetabolism within the cortex, resulting in altered neuronal excitability. We hypothesized to see disease-dependent alterations functional connectivity and grey matter volume regions associated perception. Methods. 19 VS 16 sex age-matched controls were recruited. Functional magnetic resonance imaging (fMRI) was applied examine resting-state (rsFC). Volume...
Purpose: Accurate and precise navigation in space postural stability rely on the central integration of multisensory input (vestibular, proprioceptive, visual), weighted according to its reliability, continuously update internal estimate direction gravity. In this study, we examined both peripheral vestibular functions a world-renowned 53-year-old male tightrope walker investigated extent which his exceptional performance was reflected our findings. Methods: Comprehensive assessments were...
The aims of this study were to implement a protocol for simultaneous multislice (SMS) accelerated diffusion-weighted imaging (DWI) the kidneys and perform systematic analysis image quality data sets.Ten healthy subjects 5 patients with renal masses underwent DWI kidney in prospective institutional review board-approved on 3 T magnetic resonance scanner. Simultaneous echo-planar sequences (acceleration factors [AFs] 2 3) compared conventional as reference standard each acquisition scheme....
Abstract Objective To improve quantitative cerebrovascular reactivity ( CVR ) measurements and CO 2 arrival times, we present an iterative analysis capable of decomposing different temporal components the dynamic carbon dioxide‐ Blood Oxygen‐Level Dependent ‐ BOLD relationship. Experimental Design Decomposition parameters included a redefinition voxel‐wise time, separation from vascular response to stepwise increase in (Delay signal Plateau – DTP decrease Baseline DTB ). Twenty‐five (normal)...
The aim of this study was to investigate the feasibility accelerated diffusion tensor imaging (DTI) skeletal muscle using echo planar (EPI) applying simultaneous multislice excitation with a blipped controlled aliasing in parallel results higher acceleration unaliasing technique.After federal ethics board approval, lower leg muscles 8 healthy volunteers (mean [SD] age, 29.4 [2.9] years) were examined clinical 3-T magnetic resonance scanner 15-channel knee coil. EPI performed at b value 500...
To study blood oxygen level-dependent cerebrovascular reactivity (BOLD-CVR) as a surrogate imaging marker for crossed cerebellar diaschisis (CCD).Twenty-five participants with symptomatic unilateral steno-occlusive disease underwent BOLD-CVR and an acetazolamide challenged (15O)-H2O-PET study. CCD asymmetry index were determined from PET compared to quantitative values. Neurologic status at admission outcome after 3 months NIH Stroke Scale (NIHSS) modified Rankin (mRS) scores.For both the...
Clinical outcomes vary substantially among individuals with large vessel occlusion (LVO) stroke. A small infarct core and imaging mismatch were found to be associated good recovery. The aim of this study was investigate whether those variables would improve individual prediction functional outcome after early (<6 h) endovascular treatment (EVT) in LVO stroke.We included 222 patients acute ischemic stroke due middle cerebral artery (MCA)-M1 who received EVT. As predictors, we used clinical...
Sensorimotor processing specifically impacts mental body representations. In particular, deteriorated somatosensory input (as after complete spinal cord injury) increases the relative weight of visual aspects parts' representations, leading to aberrancies in how images parts are mentally manipulated (e.g. rotation). This suggests that a sensorimotor or reference frame, respectively, can be relatively dominant local (hands) versus global (full-body) bodily On this basis, we hypothesized...
Abstract Introduction We elaborate on existing analysis methods for breath‐hold ( BH )‐derived cerebrovascular reactivity CVR ) measurements and describe novel insights models toward more exact interpretation. Methods Five blood‐oxygen‐level‐dependent BOLD fMRI datasets of neurovascular patients with unilateral hemispheric hemodynamic impairment were used to test various methods. Temporal lag (phase), percent signal change ), explained variance (coherence) maps calculated using three...
Abstract Neuroimaging studies on anorexia nervosa (AN) have consistently reported globally reduced gray matter in patients with acute AN. While first adolescent AN provide evidence for the reversibility of these impairments after weight gain, longitudinal detailed regional analysis adult are lacking and factors associated brain restitution poorly understood. We investigated structural changes using T1-weighted magnetic resonance images surface-based morphometry. The sample consisted 26 women...
Functional stereotactic neurosurgery by means of deep brain stimulation or ablation provides an effective treatment for movement disorders, but the outcome surgical interventions depends on accuracy which target structures are reached. The purpose this pilot study was to evaluate feasibility diffusion tensor imaging (DTI) based probabilistic tractography that commonly used pre- and perioperative targeting functional neurosurgery. Three targets were reconstructed their significance as...