A5078044300- Probiotics and Fermented Foods
- Gut microbiota and health
- Diet and metabolism studies
- Trace Elements in Health
- Genetics, Aging, and Longevity in Model Organisms
- Retinoids in leukemia and cellular processes
- Bacteriophages and microbial interactions
- Milk Quality and Mastitis in Dairy Cows
- Identification and Quantification in Food
- Heavy Metal Exposure and Toxicity
- Nutrition, Genetics, and Disease
- Aluminum toxicity and tolerance in plants and animals
- Infant Nutrition and Health
- Essential Oils and Antimicrobial Activity
- Medicinal Plants and Neuroprotection
- Iron Metabolism and Disorders
- Salmonella and Campylobacter epidemiology
- Microbial Metabolism and Applications
- Antimicrobial Resistance in Staphylococcus
- Consumer Attitudes and Food Labeling
- Antioxidant Activity and Oxidative Stress
- Edible Oils Quality and Analysis
- Dietary Effects on Health
- Folate and B Vitamins Research
- Endoplasmic Reticulum Stress and Disease
Consiglio per la ricerca in agricoltura e l’analisi dell’economia agraria
2013-2024
Cereal Research Centre
2017-2021
Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione
2002-2016
Sapienza University of Rome
2009
A complex and heterogeneous microflora performs sugar lactic acid fermentations in food products. Depending on the fermentable matrix (dairy, meat, vegetable etc.) as well species composition of microbiota, specific combinations molecules are produced that confer unique flavor, texture, taste to each product. Bacterial populations within such "fermented microbiota" often environmental origin, they persist alive foods ready for consumption, eventually reaching gastro-intestinal tract where...
Table olives are increasingly recognised as a vehicle well source of probiotic bacteria, especially those fermented with traditional procedures based on the activity indigenous microbial consortia, originating from local environments. In present study, we report characterisation at species level 49 Lactic Acid Bacteria strains deriving Nocellara del Belice table Spanish or Castelvetrano methods, recently isolated in our previous work. Ribosomal 16S DNA analysis allowed identification 4...
Ageing is often characterised by nutritional deficiencies and functional alterations of the digestive immune system. The aim present study was to analyse impact consumption conventional milk with A1/A2 beta-casein, compared containing only A2 beta-casein variant, a protein profile favouring gut health. Twenty-four ageing Balb-c mice (20 months old) were fed for 4 weeks, either control diet (CTRL), supplemented bovine (A1A2) or A2/A2 (A2A2). Lymphocyte subpopulations, enzymatic activities,...
Lactic acid bacteria (LAB) are involved in several food fermentations and many of them provide strain-specific health benefits. Herein, the probiotic potential foodborne strain Lactobacillus fermentum MBC2 was investigated through vitro vivo approaches. Caenorhabditis elegans used as an model to analyze pro-longevity anti-aging effects. L. showed a high gut colonization capability compared E. coli OP50 (OP50) or rhamnosus GG (LGG). Moreover, analysis pumping rate, lipofuscin accumulation,...
ABSTRACT Food-borne antibiotic-resistant lactic acid bacteria have received growing attention in the past few years. We recently identified tetracycline-resistant Lactobacillus paracasei samples of milk and natural whey starter cultures employed manufacturing process a typical Italian fermented dairy product, Mozzarella di Bufala Campana. In present study, we characterized at molecular level genetic context tetracycline resistance determinants these strains, which as tet (M). This gene was...
The nematode Caenorhabditis elegans is widely used as a model system for research on aging, development, and host-pathogen interactions. Little currently known about the mechanisms underlying effects exerted by foodborne microbes. We took advantage of C. to evaluate impact microbiota well characterized physiological features worms. Foodborne lactic acid bacteria (LAB) consortium was feed nematodes its composition evaluated 16S rDNA analysis strain typing before after colonization gut....
Microbiological and molecular analysis of antibiotic resistance in Gram-positive cocci derived from the Italian PDO (Protected Designation Origin) dairy food product Mozzarella di Bufala Campana. One hundred seven coccal colonies were assigned to Enterococcus faecalis, Lactococcus lactis Streptococcus bovis genera by ARDRA (amplified ribosomal DNA restriction analysis). Among them, 16 Ent. 26 L. 39 Strep. displayed high minimum inhibitory concentration (MIC) values for tetracycline, while 17...
Lactic acid bacteria (LAB) represent the predominant microbiota in fermented foods. Foodborne LAB have received increasing attention as potential reservoir of antibiotic resistance (AR) determinants, which may be horizontally transferred to opportunistic pathogens. We previously reported isolation AR from raw ingredients a cheese, while genes could detected final, marketed product only by PCR amplification, thus pointing at need for more sensitive microbial techniques. turned therefore...
Lactobacillus delbrueckii represents a technologically relevant member of lactic acid bacteria, since the two subspecies bulgaricus and lactis are widely associated with fermented dairy products. In present work, we report characterization commercial strains belonging to L. bulgaricus, novel strain previously isolated from traditional fresh cheese. A phenomic approach was performed by combining metabolomic proteomic analysis three strains, which were subsequently supplemented as food source...
Obesity is a complex pathology associated with dysbiosis, metabolic alterations, and low-grade chronic inflammation promoted by immune cells, infiltrating populating the adipose tissue. Probiotic supplementation was suggested to be capable of counteracting obesity-associated microbial based on its proven immunomodulatory activity positive effect gut balance. Traditional fermented foods represent natural source live microbes, including environmental strains probiotic features, which could...
The presence of antibiotic-resistance (AR) genes in foodborne bacteria enteric origin represents a relevant threat to human health the case opportunistic pathogens, which can reach gut through food chain. Streptococcus bovis is pathogen often associated with infections immune-compromised or cancer patients, and it also be detected environment, including fermented foods. We have focused on molecular characterization tetracycline (Tet)-resistance gene present 39 isolates S. phenotypically...
ABSTRACT The M1 strain, able to grow on β-myrcene as the sole carbon and energy source, was isolated by an enrichment culture identified a Pseudomonas sp. One β-myrcene-negative mutant, called N22, obtained transposon mutagenesis, accumulated ( E )-2-methyl-6-methylen-2,7-octadien-1-ol (or myrcen-8-ol) unique biotransformation product. This compound gas chromatography-mass spectrometry. We cloned sequenced DNA regions flanking used these fragments identify genomic library clones containing...