A5066748824- Probiotics and Fermented Foods
- Trace Elements in Health
- Nutrition, Genetics, and Disease
- Nutritional Studies and Diet
- Gut microbiota and health
- Heavy Metal Exposure and Toxicity
- Iron Metabolism and Disorders
- Diet and metabolism studies
- Consumer Attitudes and Food Labeling
- Retinoids in leukemia and cellular processes
- Fungal and yeast genetics research
- Digestive system and related health
- Bioinformatics and Genomic Networks
- RNA modifications and cancer
- Identification and Quantification in Food
- Drug Transport and Resistance Mechanisms
- Plant Gene Expression Analysis
- Folate and B Vitamins Research
- Microbial Metabolism and Applications
- Bacteriophages and microbial interactions
- Barrier Structure and Function Studies
- Aluminum toxicity and tolerance in plants and animals
- Fermentation and Sensory Analysis
- Bacterial Genetics and Biotechnology
- DNA Repair Mechanisms
Consiglio per la ricerca in agricoltura e l’analisi dell’economia agraria
2013-2023
Cereal Research Centre
2017-2021
Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione
2006-2018
Hebei Medical University
2006-2011
Food & Nutrition
2011
Institut National de la Recherche Agronomique du Niger
2011
University of Salerno
2010
Sapienza University of Rome
1993
University of Rochester
1985-1986
There is clinical evidence linking asthma with the trace element, zinc (Zn). Using a mouse model of allergic inflammation, we have previously shown that labile Zn decreases in inflamed airway epithelium (Truong-Tran AQ, Ruffin RE, Foster PS, Koskinen AM, Coyle P, Philcox JC, Rofe Zalewski PD. Am J Respir Cell Mol Biol 27: 286-296, 2002). Moreover, mild nutritional deficiency worsens lung function. Recently, number proteins belonging to Solute Carrier Family 39 (ZIP) and 30 (ZnT) been...
A complex and heterogeneous microflora performs sugar lactic acid fermentations in food products. Depending on the fermentable matrix (dairy, meat, vegetable etc.) as well species composition of microbiota, specific combinations molecules are produced that confer unique flavor, texture, taste to each product. Bacterial populations within such "fermented microbiota" often environmental origin, they persist alive foods ready for consumption, eventually reaching gastro-intestinal tract where...
We have identified the Dri 27 cDNA on basis of its upregulated expression during rat intestinal development. It encodes a hydrophobic protein 430 amino acids that shares significant homology with members mammalian zinc transporter family ZnT. The murine homologue (named ZnT4) was recently associated mouse mutation “lethal milk.” primary sequence 27/ZnT4 displays features characteristic polytopic membrane proteins. In this paper, we show is localized in intracellular vesicles, majority which...
Table olives are increasingly recognised as a vehicle well source of probiotic bacteria, especially those fermented with traditional procedures based on the activity indigenous microbial consortia, originating from local environments. In present study, we report characterisation at species level 49 Lactic Acid Bacteria strains deriving Nocellara del Belice table Spanish or Castelvetrano methods, recently isolated in our previous work. Ribosomal 16S DNA analysis allowed identification 4...
The RAD7 gene of Saccharomyces cerevisiae was cloned on a 4.0-kilobase (kb) DNA fragment and shown to provide full complementation rad7-delta mutant strain. nucleotide sequence 2.2-kb which contains the complete determined. Transcription initiates at multiple sites in region spanning positions -61 -8 sequence. 1.8-kb mRNA encodes protein 565 amino acids with predicted size 63.7 kilodaltons. hydropathy profile indicates highly hydrophilic terminus very hydrophobic toward carboxyl terminus. A...
A search for novel genes that are up-regulated during development and differentiation of the epithelial cells intestinal mucosa led us to isolation Dri 42 cDNA clone (Dri, differentially expressed in rat intestine). The nucleotide sequence full-length has shown it encodes a 35.5-kDa protein with one consensus N-linked glycosylation alternating hydrophilic hydrophobic domains. To determine intracellular localization we have raised polyclonal antibodies hens against bacterially produced...
ABSTRACT Food-borne antibiotic-resistant lactic acid bacteria have received growing attention in the past few years. We recently identified tetracycline-resistant Lactobacillus paracasei samples of milk and natural whey starter cultures employed manufacturing process a typical Italian fermented dairy product, Mozzarella di Bufala Campana. In present study, we characterized at molecular level genetic context tetracycline resistance determinants these strains, which as tet (M). This gene was...
Micronutrients influence multiple metabolic pathways including oxidative and inflammatory processes. Optimum micronutrient supply is important for the maintenance of homeostasis in metabolism and, ultimately, maintaining good health. With advances systems biology genomics technologies, it becoming feasible to assess activity single micronutrients their complete biological context. Existing research collects fragments information, which are not stored systematically thus optimally...
The remarkable progress in characterizing the human genome sequence, exemplified by Human Genome Project and HapMap Consortium, has led to perception that knowledge tools (e.g., microarrays) are sufficient for many if not most biomedical research efforts. A large amount of data from diverse studies proves this inaccurate at best, worst, an impediment further efforts characterize variation genome. Because genotype environment fundamental basis understand phenotypic variability heritability...
The nematode Caenorhabditis elegans is widely used as a model system for research on aging, development, and host-pathogen interactions. Little currently known about the mechanisms underlying effects exerted by foodborne microbes. We took advantage of C. to evaluate impact microbiota well characterized physiological features worms. Foodborne lactic acid bacteria (LAB) consortium was feed nematodes its composition evaluated 16S rDNA analysis strain typing before after colonization gut....
Microbiological and molecular analysis of antibiotic resistance in Gram-positive cocci derived from the Italian PDO (Protected Designation Origin) dairy food product Mozzarella di Bufala Campana. One hundred seven coccal colonies were assigned to Enterococcus faecalis, Lactococcus lactis Streptococcus bovis genera by ARDRA (amplified ribosomal DNA restriction analysis). Among them, 16 Ent. 26 L. 39 Strep. displayed high minimum inhibitory concentration (MIC) values for tetracycline, while 17...