A5068839210- Pharmacological Effects and Toxicity Studies
- Drug-Induced Hepatotoxicity and Protection
- Chemotherapy-induced organ toxicity mitigation
- Nanoparticles: synthesis and applications
- Phytochemicals and Antioxidant Activities
- Drug Transport and Resistance Mechanisms
- Advances in Cucurbitaceae Research
- Advanced Drug Delivery Systems
- Healthcare and Venom Research
- Curcumin's Biomedical Applications
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Natural Antidiabetic Agents Studies
- Nigella sativa pharmacological applications
- Cynara cardunculus studies
- Ergonomics and Human Factors
- Aerogels and thermal insulation
- Phytochemicals and Medicinal Plants
- Ginger and Zingiberaceae research
- Cardiovascular Function and Risk Factors
- Chemotherapy-induced cardiotoxicity and mitigation
- Otitis Media and Relapsing Polychondritis
- Pomegranate: compositions and health benefits
- Qur’anic Interpretation Studies
- Phytochemical and Pharmacological Studies
Qingdao University of Science and Technology
2023-2025
Ocean University of China
2020-2025
Pakistan Institute of Medical Sciences
2017-2023
GlycoScientific (United States)
2022
Islamia University of Bahawalpur
2021
Punjab Medical College
2018
Shaikh Zayed Postgraduate Medical Institute
2018
University Hospitals of Leicester NHS Trust
2015
University Hospital Galway
2010
The global transplantation market size was valued at USD 8.4 billion in 2020 and is expected to grow a compound annual growth rate of 11.5% over the forecast period. increasing demand for tissue has inspired researchers find alternative approaches making artificial tissues organs function. unique physicochemical biological properties biopolymers attractive structural characteristics aerogels such as extremely high porosity, ultra low-density, surface area make combining these materials great...
The current study aims to assess the beliefs of general public in Pakistan towards conspiracy theories, acceptance, willingness pay, and preference for COVID-19 vaccine. A cross-sectional was conducted through an online self-administered questionnaire during January 2021. Chi-square test or Fisher exact utilized statistical data analysis. total 2158 respondents completed questionnaire, among them 1192 (55.2%) were male with 23.87 (SD: ±6.23) years as mean age. circulating regarding vaccine...
Non-alcoholic steatohepatitis (NASH) is a primary cause of cirrhosis and hepatocellular carcinoma. Unfortunately, there no approved drug treatment for NASH. AMP-activated kinase (AMPK) an important metabolic sensor whole-body regulator. It has been proposed that AMPK activators could be used treating diseases such as obesity, type 2 diabetes In this study, we screened marine natural compound library by monitoring activity found potent activator, candidusin A (CHNQD-0803). Further studies...
We aimed to investigate the pharmacologic mechanism underlying this traditional remedy. used a freshly produced hot water decoction of J. sambac leaves (HWDJS) examine its hepatoprotective effects in laboratory animals, administering doses HWDJS at 100, 200, and 300 mg/kg over 7 days. On 8th day, paracetamol toxicity was induced dose 2 g/kg. The test control groups assessed biochemical indicators (alkaline phosphatase, aspartate transaminase, alanine C-reactive protein), liver-to-body weight...
The study aimed to evaluate the synergistic effects of Majoon-e-Suranjaan with and without isometric exercises in patients rheumatoid arthritis (RA). A prospective, pragmatic, community based, parallel group, single blinded randomized controlled trial conducted at Muhammad Physical Therapy Rehabilitation Clinic Centre, Multan, from May October 2023. was approved registered Iranian Registry Clinical Trials (IRCT20230202057310N5). Ninety-five were randomly assigned two groups. Group received...
Currently the stretchable knitted fabrics are extensively used as compression bandages in clinics. In present study, we have fabricated antibacterial medicated textiles (bandages, bandages). The study was composed of three parts. At first, versatile one-pot green synthesis approach to form a stable and concentrated solution silver nanoparticles (Ag-NPs) through self-assembly tannic acid (capping agent). Tannic (hygienic capping agent) serving dispersant reductant, also acts agent while...
Abstract Gemcitabine (GC)-loaded chitosan nanoparticles were synthesized by ionic gelation method, and optimization was accomplished Box–Behnken design based on particle size (PS), polydispersity index (PDI), zeta potential (ZP), percent entrapment efficiency (% EE). The optimized formulation (OF) exhibited PS, PDI, ZP, % EE to be 206.7 nm, 0.285, +27 mV, 77.61%, respectively. Fourier transform infrared spectroscopy, X-ray diffraction analysis, differential scanning calorimetry analyses...
In recent years, pH-sensitive hydrogels have been developed for the delivery of therapeutic agents to specific target sites that a defined pH range. The use pH-responsive polymers in allows drug desired range organ. primary aim is increase retention time small intestine by utilizing swelling mechanism hydrogel at intestinal pH. this study, polyethylene glycol (PEG) was used as polymer formulate Ezetimibe deliver where it inhibits absorption cholesterol. Design Expert software applied design...
Jasminum sambac (L.) is a South Asian folkloric medicinal plant that has traditionally been used to treat cardiovascular problems. The current investigation was meticulously organized explore the pharmacological foundation for uses of J. pertaining ailments and investigate core mechanisms. Mechanistic revealed crude leaf extract produced ex-vivo vasorelaxant effects in endotheliumintact aorta ring preparation hypotensive effect recorded via pressure force transducers coupled Power Lab Data...
Despite many liver disorders, clinically useful drugs are scarce. Moreover, the available therapies facing challenges of efficacy and safety. Alhagi camelorum has been used in folk medicine globally for millennia to treat several ailments. (Ac) is an old plant with a significant therapeutic value throughout Africa, Asia, Latin America. Our goal was determine hepatoprotective activity against valproic acid induced hepatotoxicity using animal model.The animals were segregated 4-groups (6 male...
Tenofovir alafenamide (TAF) is an antiretroviral (ARV) drug that used for the management and prevention of human immunodeficiency virus (HIV). The clinical availability ARV delivery systems provide long-lasting protection against HIV transmission lacking. There a dire need to formulate nanocarrier can help in revolutionizing way fight HIV/AIDS. Here, we aimed synthesize polymer using chitosan polyethylene glycol (PEG) by PEGylation at hydroxyl group. After successful modification...
Formulate a gel and test its scientific efficacy for treating musculoskeletal ailments with or without phonophoresis.
Chronic obstructive pulmonary disease (COPD) is associated with substantial humanistic and socioeconomic burden on patients their caregivers. COPD expected to be 7th leading cause of till 2030. The objective the current study was assess caregivers in Malaysia. includes cost management COPD, QOL caregivers, work productivity activity impairment due COPD. One hundred fifty from chest clinic Penang Hospital were included August 2018 2019. Caregiving estimated using replacement approach, while...
Alhagi camelorum (AC) is an old plant with a significant therapeutic value throughout Africa, Asia, and Latin America. The overuse of cisplatin (Cis > 50 mg/m2) associated observed nephrotoxicity, ototoxicity, gastrotoxicity, myelosuppression, allergic reactions. Remedial measures are needed for the protection nephrotoxicity against cisplatin. Thus, we investigated nephroprotective effects AC extract to prevent cisplatin-induced in albino Wistar rats. presence polyphenols, phenolic...
Jatropha mollissima is one of the ancient plants that known in Africa, Asia and Latin America for its high medicinal value. Previously we showed ethanolic leaves extract J. was able to reverse aminoglycoside antibiotics induced nephrotoxicity only two weeks administration. Here, evaluated phytochemicals, antioxidant vivo cytotoxicity addition ability reversing Cisplatin-induced wistar albino rats. The results phytochemical analysis presence flavonoids, phenols, tannins saponins, with...
The current study was aimed to design a thiolated chitosan (TC) based mucoadhesive nanoparticle (NP) formulation for enhancing the oral bioavailability of an anti-coagulant, Ticagrelor (TG). Nanoparticles (NPs) containing naturally occurring biodegradable polymers have been revealed as promising carriers controlled delivery various therapeutic agents through route. Ionic gelation technique adopted prepare nanoparticles TG (TCNPs/TG) and (CH) (CHNPs/TG) by varying concentration with respect...
Currently, the solid lipid nanoparticles (SLNs) are utilized as a novel approach for controlled drug delivery system (CDDS). Tacrolimus (TCM), lipophilic drug, can easily be encapsulated in hydrophobic core of these SLNs using nanoprecipitation technique. The current aim was to develop release Poloxamer (PLX) facilitated TCM loaded (PLX/TCM-SLNs), followed by their physicochemical evaluations, including chemical compatibility, particle size, surface charge, morphology, nature SLNs, loading...
Background: Pain remains a global public heath priority. Phonophoresis, also known as sonophoresis or ultrasonophoresis, is when an ultrasound used to maximize the effects of topical drug. Purpose: The objective this study was test, in patients injured sports accidents (N = 200), efficacy diclofenac potassium (DK) 6%, 4%, and 2% formulated gels with without phonophoresis comparison market available standard sodium (DS DN) gel. Methods: were enrolled after informed consent. By using lottery...