A5101781678- Inflammatory Bowel Disease
- Microscopic Colitis
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Eosinophilic Esophagitis
- Gallbladder and Bile Duct Disorders
- Immunodeficiency and Autoimmune Disorders
- Pancreatic and Hepatic Oncology Research
- Diagnosis and treatment of tuberculosis
- Autoimmune and Inflammatory Disorders
- Helicobacter pylori-related gastroenterology studies
- Global Health Care Issues
- Healthcare Policy and Management
- Pancreatitis Pathology and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Gastrointestinal Bleeding Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Economic and Financial Impacts of Cancer
- Patient Satisfaction in Healthcare
- Dermatological and COVID-19 studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Nonmelanoma Skin Cancer Studies
- Global Maternal and Child Health
- Appendicitis Diagnosis and Management
University of Washington
2014-2024
Boston Medical Center
2013-2015
Boston University
2015
Using Truven Health MarketScan Databases, we examined prescription opioid use in patients with inflammatory bowel disease (IBD) and the resultant increase of emergency services rise healthcare costs among these patients.
Currently, the predictors of readmission after colectomy specifically for ulcerative colitis (UC) are poorly investigated. We sought to determine rates and 30-day readmissions UC.Patients undergoing total proctocolectomy end ileostomy, abdominal with ileoanal pouch anastomosis (IPAA) formation diverting one stage IPAA, or ileorectal at a tertiary care center between January 2002 2012 UC were included. Patients identified using ICD-9 code 556.x. Each record was manually reviewed. The...
Abstract Background The majority of patients with Crohn’s disease (CD) will not achieve endoscopic remission on current therapy. Addition tofacitinib to biologics may improve rates. Methods We retrospectively assessed safety and clinical effectiveness off-label for CD. Results identified 19 treated a biologic refractory CD between 2017 2019. Tofacitinib was added luminal colonoscopy (n = 13), capsule 3), pyoderma gangrenosum 3). mean age 41.2 years (28–62), duration 16.9 (6–36), prior...
Background Antibiotics have been used to treat luminal Crohn's disease with variable success. Rifaximin has a favourable safety profile given its limited systemic absorption and may improve clinical symptoms in patients mild moderate disease. Response of severe rifaximin therapy is unclear. We aimed evaluate the response treatment moderately severely active Methods Subjects (Crohn's activity index 250-450) were randomised 1:1 blinded 550 mg PO BID or placebo for 8 weeks. Nonresponders...
Objective: Multidisciplinary cancer consultations play a critical role in the delivery of quality care by promoting treatment planning and collaborative decision-making. The objective this study was to evaluate associations between multidisciplinary receipt guideline-recommended adjuvant treatments among breast, colorectal, or non-small cell lung patients assess these within racial ethnic groups. Methods: This is population-based retrospective cohort using Surveillance, Epidemiology, End...
Introduction: Walled-off necrosis (WON) as sequelae of severe acute, necrotizing pancreatitis has been associated with high morbidity and mortality. Both sterile WON infected can lead to multiorgan failure, generally held opinions suggesting worse outcomes in WON. There is a dearth studies specifically comparing between Methods: All patients undergoing minimally invasive treatment for symptomatic or have maintained prospectively collected institutional database since October 2007. We...
Purpose: The Institute of Medicine notes that guidelines summarize current research to create a safer medical system. While older studies recommended antibiotic prophylaxis prior endoscopy, the AHA revised their in 2007 recommending against prophylaxis. Similarly, ASGE updated 2008 antibiotics, and 2009 regarding antiplatelets endoscopy. Methods: An IRB approved survey was developed from for antibiotic/antiplatelet before Primary care medicine subspecialist including attendings housestaff...
Introduction: Gallstones are the most common etiology of acute pancreatitis (AP). Endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and/or stone extraction could be beneficial in preventing recurrence. Previous trials showed no effect on in-hospital outcomes such as mortality, complications, severity, and length stay. We examined association between ERCP during an admission for AP due to gallstones later emergent encounters readmissions recurrent pancreatitis....
Introduction: Patients with inflammatory bowel disease (IBD) depression and other psychosocial issues such as chronic pain experience poorer health outcomes quality of life. We sought to examine if these also predicted higher utilization emergent services cost. Methods: A retrospective cohort study using the Truven Health Marketscan Databases from 2009-2010, which capture clinical across inpatient outpatient settings, including drug claims, for subjects employer-based insurance was...
Introduction: Tumor necrosis factor (TNF) antagonists are effective treatments for moderate-severe Crohn's disease (CD). Up to one third of patients have primary-nonresponse TNF therapy, which has been reported predict low rates response subsequent agents. No study date specifically assessed the effectiveness intravenously (IV) administered therapy following subcutaneously (SC) TNF. We hypothesize that IV administration and weight-based dosing offers advantages over SC fixed dose TNFs may be...
Introduction: Tumor necrosis factor-alpha antagonists (anti-TNF) therapies have been shown to be very effective for the treatment of ulcerative colitis (UC). Certolizumab pegol (CZP) is an anti-TNF that induction response in Crohn's disease but has not studied UC. Given proven effectiveness other agents treating UC, this pilot study aimed further evaluate off-label CZP clinical and endoscopic remission subjects with moderate-to-severe Methods: 17 eligible per protocol active UC (Complete...
Introduction: People with CF (PwCF) experience increased rates of early colon polyp development and progression to colorectal cancer compared the general population; a trend further magnified in patients solid organ transplant. The exact mechanism for why develop more polyps whether different types occur at similar prevalence as population remains unclear. We developed database colonoscopy results PwCF better characterize location varying types. Methods: In this retrospective chart review,...