- Solar and Space Plasma Dynamics
- Astro and Planetary Science
- Geomagnetism and Paleomagnetism Studies
- Cerebrospinal fluid and hydrocephalus
- Geophysics and Gravity Measurements
- Stellar, planetary, and galactic studies
- Fetal and Pediatric Neurological Disorders
- Solar Radiation and Photovoltaics
- Ionosphere and magnetosphere dynamics
- Spinal Dysraphism and Malformations
- Botany, Ecology, and Taxonomy Studies
- Advanced Neuroimaging Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Geophysics and Sensor Technology
- Scientific Research and Discoveries
- Oceanographic and Atmospheric Processes
- Fluid Dynamics and Turbulent Flows
- Botany and Plant Ecology Studies
- Historical Astronomy and Related Studies
- Meteorological Phenomena and Simulations
- Renal Transplantation Outcomes and Treatments
- Pulsars and Gravitational Waves Research
- Astrophysics and Star Formation Studies
- Rangeland and Wildlife Management
- Archaeology and Natural History
University of Rochester
2009-2025
Florida International University
2009-2021
Phoenix Houses of New England
2021
Mott MacDonald (United Kingdom)
2017
Oregon Medical Research Center
2017
Oregon Health & Science University
2017
Fort Environmental Laboratories (United States)
2003-2006
University of Cambridge
1966-2005
Isaac Newton Institute for Mathematical Sciences
2005
Auburn University
1998
Flow of cerebrospinal fluid (CSF) through perivascular spaces (PVSs) in the brain is important for clearance metabolic waste. Arterial pulsations are thought to drive flow, but this has never been quantitatively shown. We used particle tracking quantify CSF flow velocities PVSs live mice. pulsatile and driven primarily by cardiac cycle. The speed arterial wall matches that CSF, suggesting motion principal driving mechanism, via a process known as pumping. Increasing blood pressure leaves...
Spreading edema after stroke The brain is enveloped in a cushion of cerebrospinal fluid (CSF), which normally provides protection and helps to remove metabolic waste. CSF transport has also recently been shown play unexpected roles neurodegeneration sleep. Mestre et al. used multimodal vivo imaging rodents found that, stroke, an abnormally large volume rushes into the brain, causing swelling (see Perspective by Moss Williams). This influx caused constrictions arteries triggered well-known...
The flow of cerebrospinal fluid along perivascular spaces (PVSs) is an important part the brain’s system for delivering nutrients and eliminating metabolic waste products (such as amyloid-β); it also offers a pathway delivery therapeutic drugs to brain parenchyma. Recent experimental results have resolved several questions about this flow, setting stage advances in our understanding its dynamics. This review summarizes new evidence provides critical evaluation previous fluid-dynamic models...
Purpose This paper aims to review the extant hospitality and tourism literature on state of robotics artificial intelligence (AI) in service industry. The aim was highlight current areas research this emerging topic identify for future application study. Design/methodology/approach A list journals used articles related AI using terms AI, robots, robotics, tourism, several combinations thereof. Additional sources were identified through reviews from works. Findings findings revealed studies...
Periarterial spaces (PASs) are annular channels that surround arteries in the brain and contain cerebrospinal fluid (CSF): a flow of CSF these is thought to be an important part brain's system for clearing metabolic wastes. In vivo observations reveal they not concentric, circular annuli, however: outer boundaries often oblate, form inner offset from central axis.
Cerebrospinal fluid (CSF) flowing through periarterial spaces is integral to the brain’s mechanism for clearing metabolic waste products. Experiments that track tracer particles injected into cisterna magna (CM) of mouse brains have shown evidence pulsatile CSF flow in perivascular surrounding pial arteries, with a bulk same direction as blood flow. However, driving remains elusive. Several studies suggested might be an artifact, driven by injection itself. Here, we address this hypothesis...
Circulation of cerebrospinal fluid and interstitial around the central nervous system through brain transports not only those water-like fluids but also any solutes they carry, including nutrients, drugs, metabolic wastes. Passing tissue primarily during sleep, this circulation has implications for neurodegenerative disorders Alzheimer's disease, damage stroke cardiac arrest, flow-related such as hydrocephalus syringomyelia. Recent experimental results reveal several features flow, other...
Flow of cerebrospinal fluid (CSF) through perivascular spaces (PVSs) in the brain delivers nutrients, clears metabolic waste, and causes edema formation. Brain-wide imaging cannot resolve PVSs, high-resolution methods access deep tissue. However, theoretical models provide valuable insight. We model CSF pathway as a network hydraulic resistances, using published parameter values. A few parameters (permeability PVSs parenchyma, dimensions astrocyte endfoot gaps) have wide uncertainties, so we...
Quantifying the flow of cerebrospinal fluid (CSF) is crucial for understanding brain waste clearance and nutrient delivery, as well edema in pathological conditions such stroke. However, existing vivo techniques are limited to sparse velocity measurements pial perivascular spaces (PVSs) or low-resolution from brain-wide imaging. Additionally, volume rate, pressure, shear stress variation PVSs essentially impossible measure vivo. Here, we show that artificial intelligence velocimetry (AIV)...
▪ Abstract Important physical processes on the Sun, and especially in sunspots, occur spatial scales at or below limiting resolution of current solar telescopes. Over past decade, using a number new techniques, high-resolution observations have begun to reveal complex thermal magnetic structure sunspot, along with associated flows oscillations. During this time remarkable advances computing power allowed significant progress our theoretical understanding dynamical processes, such as...
Intracranial cerebrospinal and interstitial fluid (ISF) flow solute transport have important clinical implications, but limited in vivo access to the brain interior leaves gaping holes human understanding of nature these neurophysiological phenomena. Models can address some gaps, only insofar as model inputs are accurate. We perform a sensitivity analysis using Monte Carlo approach on lumped-parameter network ISF perivascular extracellular spaces murine brain. place bounds predictions given...
view Abstract Citations (110) References (22) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Siphon Flows in Isolated Magnetic Flux Tubes Thomas, John H. Previous studies of siphon flows magnetic flux tubes have been limited to the case a low-β plasma, appropriate for an embedded tube solar corona or chromosphere. Here author steady isolated, thin surrounded by field-free gas, with plasma β ≥ 1, conditions photosphere. The presents basic equations...
A theoretical treatment of magneto-atmospheric waves is presented and applied to the modelling in solar atmosphere. The arise compressible, stratified, electrically conductive atmospheres within gravitational fields when permeated by a magnetic field. Compression, buoyancy, distortion field all contribute existence waves. Basic linearized equations are introduced describe attention given plane-stratified their stability. dispersion relation defined for wave propagation atmosphere there no...