A5100414301- Aquaculture disease management and microbiota
- Vibrio bacteria research studies
- Aquaculture Nutrition and Growth
- Physiological and biochemical adaptations
- Fish Ecology and Management Studies
- Marine Bivalve and Aquaculture Studies
- Water Quality Monitoring Technologies
- Bacterial biofilms and quorum sensing
- Constructed Wetlands for Wastewater Treatment
- Legionella and Acanthamoeba research
- Viral gastroenteritis research and epidemiology
- Invertebrate Immune Response Mechanisms
- Coastal wetland ecosystem dynamics
- Child Nutrition and Water Access
- Bacterial Genetics and Biotechnology
- Coagulation and Flocculation Studies
- Zoonotic diseases and public health
- Myxozoan Parasites in Aquatic Species
- Viral Infections and Outbreaks Research
- Genetic diversity and population structure
- Polysaccharides Composition and Applications
- Adsorption and biosorption for pollutant removal
- Therapeutic Uses of Natural Elements
- Echinoderm biology and ecology
- Enzyme Structure and Function
Dalian Ocean University
2017-2024
Zhejiang University
2022-2024
North China University of Technology
2023
University at Buffalo, State University of New York
2023
Qinghai University
2022
Chinese Academy of Sciences
2017-2021
Ministry of Education of the People's Republic of China
2020-2021
Institute of High Energy Physics
2021
Dalian University
2019
Dalian University of Technology
2019
Bacterial persister cells are dormant and highly tolerant to lethal antibiotics, which believed be the major cause of recurring chronic infections. Activation toxins bacterial toxin-antitoxin systems inhibits growth plays an important role in formation. However, little is known about overall gene expression profile upon toxin activation. More importantly, how persisters evade host immune clearance remains poorly understood. Here we demonstrate that a Pseudomonas aeruginosa system HigB-HigA...
Abstract Background Human-use probiotics have recently been associated with clinical infections and antibiotic resistance transfer, raising public concern over their safety. However, despite extensive application in aquaculture animal husbandry, the safety of animal-use remains poorly described. Methods We evaluated 92 from China. The pattern spread pathogens consequent health implications were also examined by conducting in-field genomic surveillance at 2 farms. Results A total 123...
Vibrio parahaemolyticus is an important foodborne pathogen and has recently gained particular notoriety because it causes acute hepatopancreatic necrosis disease (AHPND) in shrimp, which caused significant economic loss the shrimp industry. Here, we report a whole-genome analysis of 233 V. strains isolated from humans, diseased environmental samples collected between 2008 2017, providing unprecedented insight into historical spread AHPND. The results show that genetically diverse can be...
Microorganisms play an essential role in the performance of constructed wetlands (CWs) for wastewater treatment. However, there has been limited discussion on characteristics microbial communities CWs treatment effluents from marine recirculating aquaculture systems (RAS). This study is aimed at characterizing pilot-scale with Salicornia bigelovii saline a land-based Atlantic salmon RAS plant located Northern China. Illumina high-throughput sequencing was employed to identify profile three...
Acute hepatopancreatic necrosis disease (AHPND) is an emerging penaeid shrimp caused by Vibrio parahaemolyticus. Although V. parahaemolyticus has been isolated and sequenced from several Asia countries, the epidemiological links among AHPND outbreaks in different locations remain unclear. In this study, we genomes of nine strains China between 2014 2016 four sampling sites three provinces. Analysis single nucleotide polymorphisms (SNPs) isolates yielded average 35,519 SNPs per isolate,...
Vibrio harveyi is one of the major pathogens in aquaculture. To identify key virulence factors affecting pathogenesis V. towards fish, we conducted a field investigation for three representative fish farms infected with harveyi. Multilocus sequence typing (MLST) and whole-genome sequencing were to delineate phylogenetic relationship genetic divergence A total 25 strains isolated from diseased groundwater subtyped into 12 types by MLST. Five genes, mshB, pilA, hutR, ureB, ureG, variably...
Protozoan grazing is a major cause of bacterial mortality and controls population size composition in the natural environment. To enhance their survival, bacteria evolved many defense strategies to avoid by protists. Cell wall modification one that helps escape from recognition and/or internalization its predators. Lipopolysaccharide (LPS) component Gram-negative cell wall. LPS divided into three regions: lipid A, oligosaccharide core O-specific polysaccharide. O-polysaccharide as outermost...
Abstract Pomacea canaliculata is one of the most notorious invasive aquatic snail, capable influencing various organisms through their secretions. Limnodrilus hoffmeisteri and Propsilocerus akamusi are prevalent powerful bioturbators in ecosystems. However, mechanism P. 's secretions affecting remains unknown. This study aimed to investigate effects secretion on L. . were treated for 24 h with native species Bellamya aeruginosa at different densities (1 or 20). The migration numbers...
Abstract Aeromonas salmonicida ( A . ) is a pathogenic bacterium that causes furunculosis and poses significant global risk, particularly in economic activities such as Atlantic salmon (Salmo salar) farming. In previous study, we identified proteins are significantly upregulated kidneys of challenged with Phosphoproteomic analyses were conducted to further clarify the dynamic changes protein phosphorylation patterns triggered by bacterial infection. To our knowledge, this first study...
The estuary is the ecological niche of pathogenic Vibrio spp. as it provides abundant organic and inorganic nutrients from seawater rivers. However, little known about ecology these species in inland brackish water area. In this study, their co-occurrence relationships to key environmental constraints (salinity temperature) Hun-Tai River China were examined using most probable number polymerase chain reaction (MPN-PCR) approach. We hereby report 2-year continuous surveillance based on six...
Our ability to predict evolutionary trajectories of pathogens is one the promising leverages fight against pandemic disease, yet few studies have addressed this question in situ, due difficulty monitoring milestone events for a given pathogen and understanding strategies. In study, we monitored real-time evolution Vibrio parahaemolyticus response successive antibiotic treatment three shrimp farms North China from 2011 2018 by whole-genome sequencing. Results showed that stepwise emergence...
Green supply chain management is a crucial way to balance economic benefits and environmental impacts. As an important aquatic product in China, sea cucumber (Apostichopus japonicus) facing the dual challenges of (profit) sustainability (material input emission output). Currently, industry China lacks green supplier screening system, resulting fragmented pattern cooperation among enterprises. Core enterprises cannot assume social responsibility help guide upstream downstream jointly improve...
Two strains of Vibrio parahaemolyticus (ATCC 17802 and 33847) in shrimp, oyster, freshwater fish, pork, chicken egg fried rice were evaluated for production hemolysin exoenzymes potential importance to the pathogenicity this bacterium. The two V. produced hemolysin, gelatinase, caseinase, phospholipase, urease, DNase amylase selected food matrices. Significantly higher (p < 0.05) hemolytic activity was by > shrimp fish oyster pork. But exoenzyme activities not consistent with profile, being...