Zhijia Fang

ORCID: 0000-0002-9370-2452
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About
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Research Areas
  • Heavy Metal Exposure and Toxicity
  • Gut microbiota and health
  • Vibrio bacteria research studies
  • Probiotics and Fermented Foods
  • Mycotoxins in Agriculture and Food
  • Trace Elements in Health
  • Aquaculture disease management and microbiota
  • Meat and Animal Product Quality
  • Heavy metals in environment
  • Aluminum toxicity and tolerance in plants and animals
  • Bacterial biofilms and quorum sensing
  • Child Nutrition and Water Access
  • Environmental Toxicology and Ecotoxicology
  • Fungal and yeast genetics research
  • Protein Hydrolysis and Bioactive Peptides
  • Gastrointestinal motility and disorders
  • Insect and Pesticide Research
  • Diet and metabolism studies
  • X-ray Diffraction in Crystallography
  • Chromium effects and bioremediation
  • Hydrogen's biological and therapeutic effects
  • Crystallization and Solubility Studies
  • Iron-based superconductors research
  • Magnetic and transport properties of perovskites and related materials
  • Environmental remediation with nanomaterials

Guangdong Ocean University
2017-2025

Chinese Academy of Tropical Agricultural Sciences
2025

Dalian Polytechnic University
2022-2024

Key Laboratory of Guangdong Province
2022

Donghua University
2013-2020

Anhui Normal University
2017

Chinese Academy of Sciences
2008-2016

Shanghai Institute of Organic Chemistry
2016

University of British Columbia
2014-2015

Sichuan University
2012-2014

Purpose.: Weexamined changes of the central nervous system in patients with advanced primary open-angle glaucoma (POAG). Methods.: The clinical observational study included 15 bilateral POAG and healthy normal control subjects, matched for age sex group. Retinal nerve fiber layer (RNFL) thickness was measured by optical coherence tomography (OCT). Using a 3-dimensional magnetization-prepared rapid gradient-echo sequence (3D–MP-RAGE) magnetic resonance imaging (MRI) optimized voxel-based...

10.1167/iovs.12-9893 article EN Investigative Ophthalmology & Visual Science 2012-12-21

Chromium occurs mostly in tri- and hexavalent states the environment. Hexavalent chromium [Cr(VI)] compounds are extensively used diverse industries, trivalent [Cr(III)] salts as micronutrients dietary supplements. In present work, we report that they both induce genetic mutations yeast cells. They also cause DNA damage Jurkat cells effect of Cr(III) is greater than Cr(VI). We further show Cr(VI) through different mechanisms. intercalates interferes base pair stacking. Based on our results,...

10.1371/journal.pone.0103194 article EN cc-by PLoS ONE 2014-08-11

Polysaccharides are functional foods or drugs that can be used to alleviate heavy metal poisoning by cadmium, lead, mercury, and arsenic. Industries generate substantial quantities of toxic wastes, such as wastewater discharges, paints, electronic waste, batteries, pigments, plastics, into the environment pose a risk human health. Therefore, it is imperative eliminate accumulated ions from body environment. Heavy toxicity lead decreased energy levels impair functioning vital organs, brain,...

10.3390/foods13060853 article EN cc-by Foods 2024-03-11

We have performed a systematic photoemission study of the chemical-potential shift as function carrier doping in pnictide system based on ${\mathrm{BaFe}}_{2}{\mathrm{As}}_{2}$. The experimentally determined is consistent with prediction rigid band picture by renormalized first-principle calculations. This leads to an electron-hole asymmetry (EHA) Fermi surface (FS) nesting condition due different effective masses for FS sheets, which can be calculated from Lindhard susceptibility. built-in...

10.1103/physrevb.83.094522 article EN publisher-specific-oa Physical Review B 2011-03-16

The heavy metal cadmium is widely used and released into the environment, posing a severe threat to crops humans. Saccharomyces cerevisiae one of most commonly organisms in investigation environmental toxicity. We investigated stress adaptive mechanisms yeast by screening genome-wide essential gene overexpression library. A candidate gene, OLE1, encodes delta-9 desaturase was associated with high anti-cadmium-stress activity. results demonstrated that expression OLE1 positively correlated...

10.1128/aem.02319-16 article EN Applied and Environmental Microbiology 2016-10-29

Optical conductivity spectra sigma(omega) were used to investigate the effect of orbital ordering on electronic structure Ca2RuO4. Our LDA+U calculation predicts Ru 4d(xy) ferro-orbital at ground state, and well explains present as reported O 1s x-ray absorption spectra. Variation temperature (T) causes a large change spectral weight over several eV collapse charge gap accompanied by elongation c-axis Ru-O bond length. These results clearly indicate that d(xy) plays crucial role in...

10.1103/physrevlett.91.056403 article EN Physical Review Letters 2003-07-31

Lipopeptides possess excellent broad spectrum antimicrobial activity. Different lipopeptides have their own unique chemical structures, properties and biological activities. Quantitative analysis of the iturin surfactin homologues produced by Bacillus natto NT-6 subjected to different culture media, shaking speed rotary shaker, liquid solid fermentation methods was conducted using LC-MS. For iturins, liquid-state in Landy medium at a 160 r min-1 most suitable for maximal homologue...

10.1186/s13568-019-0845-y article EN cc-by AMB Express 2019-07-27

The bacteriocin CAMT6 is a novel produced by Enterococcus durans YQ-6 isolated from Larimichthys polyactis in the South China Sea. In this study, was purified extraction using ethyl acetate, Sephadex LH-20 column chromatography, cation exchange chromatography and reversed-phase high-performance liquid sequence. Liquid Chromatograph Triple Quadrupole Mass Spectrometer (LC-MS/MS) analysis revealed that relative molecular mass amino acid sequence of were 1254.63 Da N-GAVHDVKDVLDS, respectively....

10.1016/j.lwt.2022.114329 article EN cc-by-nc-nd LWT 2022-12-16

Fusarium oxysporum (F. oxysporum) is a common contaminant of dried fish, and the T-2 synthesis by this organism in fish products poses serious public health risk. In study, we investigated effects iturin A, cyclic lipopeptide produced Bacillus subtilis, on growth toxin F. oxysporum, transcriptomics was conducted. Results showed that inhibitory effect A significantly enhanced with an increase concentrations. More specifically, compared control group, all indexes treatment group 50 μg/mL were...

10.3390/foods12061278 article EN cc-by Foods 2023-03-17

In this study, we have developed a novel fluorescent "OFF-ON" quantum dots (QDs) sensor based on CdTe/CdS/SiO2 cores. Ammonium pyrrolidine dithiocarbamate (APDC), ethylenediamine tetraacetic acid (EDTA), and 1,10-phenanthroline (Phen) served as potential chemical etchants. Among these three etchants, APDC exhibited the most pronounced quenching effect (94.06%). The APDC-etched QDs demonstrated excellent optical properties: fluorescence of system (excitation wavelength: 365 nm emission 622...

10.1016/j.heliyon.2024.e26980 article EN cc-by Heliyon 2024-02-27

Lutjanus erythropterus protein (Lep) exhibits anti-inflammatory effects, but its antidepressant activity is unknown. This study used a 44-day chronic unpredictable mild stress (CUMS) model to determine whether Lep has beneficial effect through the gut–brain axis in 3-week-old male C57BL/6 mice. Gavaging with solution alleviated depression-like behavior and anxiety symptoms CUMS growing Administration of decreased serum IL-1β, IL-2, IL-6, TNF-α levels restored colonic mucosal damage. In...

10.3390/foods14020330 article EN cc-by Foods 2025-01-20

Systemic low-grade inflammation induced by unhealthy diet has become a common health concern as it contributes to immune imbalance and induces chronic diseases, yet effective preventions interventions are currently unavailable. The Chrysanthemum indicum L. flower (CIF) is herb with strong anti-inflammatory effect in drug-induced models, based on the theory of "medicine food homology". However, its effects mechanisms reducing food-induced systemic (FSLI) remain unclear. This study showed that...

10.3390/nu15051069 article EN Nutrients 2023-02-21

A 56-day feeding trial was conducted to evaluate the effect of different dietary protein sources on growth performance, muscle flavor substances, and quality structure Triploid Crucian Carp. Three isonitrogenous (32.00%), isolipidic (8.00%), isoenergetic (18.00 MJ kg−1) practical diets were formulated. These consisted fishmeal as animal-derived source (AP), a combination soybean meal rapeseed plant-derived (PP), mixture fishmeal, meal, mixed (MP). Each diet randomly assigned triplicate tanks...

10.3390/fishes9010023 article EN cc-by Fishes 2024-01-04

Intestinal mucosal barrier damage is regarded as the critical factor through which chronic unpredictable mild stress (CUMS) leads to a variety of physical and mental health problems. However, exact mechanism by CUMS induces intestinal unclear. In this study, 14, 28, 42 d model mice were established. The indicators related ileal (IMBD), composition microbiota its amino acid (AA) short-chain fatty (SCFA) metabolic functions, free (FAA) SCFA levels in lumen measured before after each period....

10.3390/ijms252312998 article EN International Journal of Molecular Sciences 2024-12-03
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