- Electrospun Nanofibers in Biomedical Applications
- Silk-based biomaterials and applications
- Tissue Engineering and Regenerative Medicine
- 3D Printing in Biomedical Research
- Hydrogels: synthesis, properties, applications
- Bone Tissue Engineering Materials
- biodegradable polymer synthesis and properties
- Polymer Surface Interaction Studies
- Wound Healing and Treatments
- Advanced Sensor and Energy Harvesting Materials
- Additive Manufacturing and 3D Printing Technologies
- Natural Fiber Reinforced Composites
- Graphene and Nanomaterials Applications
- Enzyme Catalysis and Immobilization
- Hemostasis and retained surgical items
- Surgical Sutures and Adhesives
- Surface Modification and Superhydrophobicity
- RNA Interference and Gene Delivery
- Intestinal and Peritoneal Adhesions
- Polymer Nanocomposite Synthesis and Irradiation
- Enzyme Production and Characterization
- Conducting polymers and applications
- Fiber-reinforced polymer composites
- Biofuel production and bioconversion
- Biopolymer Synthesis and Applications
Kumoh National Institute of Technology
2014-2025
Kyungpook National University
1996-2010
Tokyo Women's Medical University
2000-2003
Kyoto University
1997-2000
A silk nanofiber-networked bio-triboelectric generator (Silk Bio-TEG) is developed using an eco-friendly and sustainable biomaterial with strong hydrogen bonding between peptide blocks. The electrospun Silk Bio-TEG shows highly durable reliable energy harvesting performances due to its notably high surface-to-volume ratio, mechanically super-strong fibers, fracture tolerant behavior of nanofiber-networks. As a service our authors readers, this journal provides supporting information supplied...
Purpose: An important application of silver nanoparticles (Ag NPs) is their use as an antimicrobial and wound dressing material. The aim this study to investigate the morphological dependence on activity cellular response Ag NPs. Materials methods: NPs various shapes were synthesized in aqueous solution using a simple method. morphology was observed via TEM imaging. with different morphologies evaluated against microorganisms (Escherichia coli [E. coli], Staphylococcus aureus [S. aureus],...
Fabrication of functional tissue constructs using sandwiched layers cultured cells could prove to be an attractive approach engineering. Rapid detachment cell sheets is a very important recovery method that permits facile manipulation the sheet and prevents damage. To accelerate required culture substrate hydrophilic hydrophobic structural changes in response temperature alteration, poly(N-isopropylacrylamide) (PIPAAm) was grafted onto porous membranes by electron beam irradiation. Analyses...
We developed a novel method to obtain designed shape cell sheets for tissue engineering. Shaping of were achieved by the use poly(N-isopropylacrylamide) (PIPAAm) and poly(N,N'-dimethylacrylamide) (PDMAAm) temperature-responsive adhesive nonadhesive domains, respectively. These polymers covalently grafted onto culture polystyrene (TCPS) dish surfaces electron beam irradiation with mask patterns. At 37 °C, human aortic endothelial cells (HAECs) attached, spread, proliferated make monolayer...
Electrospinning has recently emerged as a leading technique for the formation of nanofibrous structures made synthetic and natural extracellular matrix components. In this study, scaffolds were obtained by electrospinning combination poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) type-I collagen in 1,1,1,3,3,3-hexafluoro-2-isopropanol (HIFP). The resulting fibers ranged from 300 to 600 nm diameter. Their surfaces characterized attenuated total reflection Fourier transform infrared...
Abstract Background In this study, silk fibroin (SF) composite hydrogels containing hydroxyapatite (HAP) nanoparticles (NPs) for bone tissue engineering were fabricated using gamma-ray (γ-ray) irradiation treatment. During the irradiation, HAP dispersed SF solution was changed to chemically crosslinked hydrogel. Methods Distribution of NPs in hydrogel examined by SEM imagery and energy dispersive X-ray spectrophotometry, crystalline structure also confirmed diffractometry. An optimum...
Abstract Poly(ethylene terephthalate) (PET)/clay nanocomposite was prepared by the direct polymerization with clay‐supported catalyst. The reaction degree of catalyst against cation exchange capacity clay 8 wt %. intercalation PET chains into silicate layers revealed X‐ray diffraction studies. SEM morphology showed a good dispersion catalyst, ranging from 30 to 100 nm. intercalated and exfoliated in matrix also observed TEM. improvement O 2 permeability for PET/clay‐supported composite films...
Bone tissue engineering aims to regenerate defected bones by combining cells, scaffolds, and growth factors. In general, bone tissues are treated with barrier membranes or guiding scaffolds achieve restoration. However, the rate of is slower than that adjacent soft tissue. Therefore, we propose patient-customizable guided regeneration (GBR) membrane-guided (GTR) scaffold hybrid constructs for precise restoration without dimensional collapse beyond critical defect size. Silk fibroin (SF)...
Overproduction of reactive oxygen species (ROS) is known to delay wound healing by causing oxidative tissue damage and inflammation. The green tea catechin, (-)-Epigallocatechin-3-O-gallate (EGCG), has drawn a great deal interest due its strong ROS scavenging anti-inflammatory activities. In this study, we developed EGCG-grafted silk fibroin hydrogels as potential dressing material.The introduction EGCG water-soluble (SF-WS) was accomplished the nucleophilic addition reaction between lysine...
Hemostatic particles have specific advantages when applied to narrow and complicated bleeding sites with convenient usage compared other types of hemostatic agents such as fabrics, foams, pastes. However, powdery are easy desorb from the surface due blood flow, which causes a serious decrease in hemostasis function. Here, we introduce bioresorbable flake particulates composed calcium alginate, starch polyacrylamide/poly(acrylic acid) ionic networks wound adhesive agent. The microstructure,...
Here we demonstrate a novel cell coculture method without any apparent limitation in cell-type combinations that exploits thermally responsive polymer-grafted patterns to alter cell–cell and cell–surface interactions. Thermally acrylamide polymer is first covalently patterned onto culture surfaces by masked electron beam irradiation. One type then cultured confluency at 37°C. Reducing temperature below 32°C selectively swells sensitive domains, detaching adherent cells only from these...
Abstract Nylon 6 nanofibers containing silver nanoparticles (nylon 6/silver) were successfully prepared by electrospinning. The structure and properties of the electrospun fibers studied with aid scanning electron microscopy, transmission energy‐dispersive spectroscopy, X‐ray diffraction. structural analysis indicated that at maximum conditions straight distributed in fibers. Finally, antibacterial activities nylon 6/silver nanofiber mats investigated a broth dilution test against...