A5026750724- Food Allergy and Anaphylaxis Research
- Chemical Synthesis and Reactions
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Mast cells and histamine
- Synthetic Organic Chemistry Methods
- Contact Dermatitis and Allergies
- Chemical Synthesis and Analysis
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Animal Virus Infections Studies
University of Notre Dame
2023-2025
Michigan Technological University
2018-2019
Virus colloidal behavior is governed by the interaction of viral surface and surrounding environment. One method to characterize virus charge isoelectric point (pI). Traditional determination pI has focused on bulk characterization a solution. However, capsids are extremely heterogeneous, single-particle may give more information range observed across population. measure chemical force microscopy (CFM). CFM technique that measures adhesion functionalized atomic microscope (AFM) probe and, in...
Peanut-induced allergy is an immunoglobulin E (IgE)–mediated type I hypersensitivity reaction that manifests symptoms ranging from local edema to life-threatening anaphylaxis. Although there are treatments for in patients with allergies resulting allergen exposure, few preventive therapies other than strict dietary avoidance or oral immunotherapy, neither of which successful all patients. We have previously designed a covalent heterobivalent inhibitor (cHBI) binds allergen-specific manner as...
The 1,3-dithiane-based dM-Dmoc group was studied for the protection of amino groups. Protection achieved under mild conditions aliphatic amines, and highly reactive less arylamines. Moderate to excellent yields were obtained. Deprotection performed by oxidation followed treating with a weak base. good excellent. new protecting offers different dimension orthogonality in reference commonly used groups terms deprotection conditions. It is expected allow collection transformations be carried...