A5021611530- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Vascular Malformations Diagnosis and Treatment
- Vasculitis and related conditions
- Stroke Rehabilitation and Recovery
- Pregnancy and preeclampsia studies
- Inflammatory Bowel Disease
- Venous Thromboembolism Diagnosis and Management
- Barrier Structure and Function Studies
- Cerebral Venous Sinus Thrombosis
- Neurological Complications and Syndromes
- Retinal and Optic Conditions
- Cerebrovascular and Carotid Artery Diseases
- Myasthenia Gravis and Thymoma
- Antiplatelet Therapy and Cardiovascular Diseases
- Vagus Nerve Stimulation Research
- Intestinal Malrotation and Obstruction Disorders
- Chronic Kidney Disease and Diabetes
- Blood Pressure and Hypertension Studies
- Mitochondrial Function and Pathology
New York Medical College
2021-2025
Westchester Medical Center
2023-2025
Johns Hopkins Hospital
2025
Richmond University Medical Center
2021
Purpose This study aimed to investigate in-patient mortality and predictors of death associated with convulsive status epilepticus (CSE) in a large nationwide cohort create simplified predictive score for in-hospital mortality. Methods Retrospective data from the National Inpatient Sample (NIS) database between 2007 2014 were analyzed, including 123,082 adults CSE. Univariate logistic testing identified admission variables, neurological medical complications A clinical prediction score,...
Background Cerebral venous thrombosis (CVT) is a rare but serious complication of traumatic brain injury (TBI), yet the implications this association remain poorly understood. This study explores demographics, risk factors, and clinical outcomes patients with both TBI CVT (CVT-TBI). Methods The National Inpatient Sample (NIS) was queried from 2016–2020 for adult primary diagnosis concurrent CVT. Chi-squared tests logistic regression were used to compare demographic, clinical, outcome...
Intracerebral hemorrhage (ICH) carries significant morbidity and mortality. Previous single-center retrospective analysis suggests that end-stage renal disease (ESRD) is a risk factor for severe ICH worse outcomes. This investigation aims to examine the impact of ESRD on severity, complications, outcomes using multicenter national database.The International Classification Disease, Ninth Tenth Revision Clinical Modification codes were used query National Inpatient Sample patients with between...
Little is known about placental drug transfer and fetal pharmacokinetics despite increasing use in pregnant women. While physiologically based pharmacokinetic (PBPK) models can help some cases to shed light on this knowledge gap, adequate parameterization of remains challenging. A novel silico model with seven compartments representing the ex vivo cotyledon perfusion assay was developed used describe acetaminophen. Unknown parameters were optimized using observed data. Thereafter, values...
Intracerebral hemorrhage (ICH) is the second most common type of stroke, accounting for approximately 10–20% all strokes, and linked to severe neurological disability death. Since accurate predictor outcome in patients with ICH hematoma volume, there a great need pharmacologic therapy that can reduce expansion resultant mass effect edema. This especially critical within ultra-early window 3–4 hours after presentation. Hemostatic therapies are exceptionally important those taking antiplatelet...
Central retinal artery occlusion (CRAO) is a rare and visually debilitating vascular condition characterized by sudden severe vision loss. CRAO compelling target for intravenous alteplase (tPA) endovascular mechanical thrombectomy (MT) due to pathophysiological similarities with acute ischemic stroke; however, the utility of these interventions in remains dubious limited sample sizes potential risks. To assess usage outcomes tPA MT CRAO, we queried National Inpatient Sample database using...
Systematic review.
Chronic inflammation of the gastrointestinal tract is a hallmark inflammatory bowel disease (IBD). This increased thought to induce hypercoagulable state that increases risk for stroke. However, few studies have examined association between IBD and acute ischemic stroke (AIS). Thus, this study aims investigate incidence, treatments, complications, outcomes AIS in patients with IBD.ICD-9-CM ICD-10-CM codes were used query National Inpatient Sample diagnosis. Baseline demographics, clinical...
The objective of this study was to investigate the prognostic significance chronic antiplatelet therapy (APT) usage in acute ischemic stroke (AIS) treated with endovascular thrombectomy (EVT). Long-term APT may enhance recanalization but also predispose patients an increased risk hemorrhagic transformation.Weighted hospitalizations for anterior-circulation AIS EVT were identified a large United States claims-based registry. Baseline clinical characteristics and outcomes compared between...
We aim to better understand the effectiveness of revascularization therapies in central retinal artery occlusion (CRAO) patients compared acute ischemic stroke (AIS) patients.
ABSTRACT Background: Atlantoaxial subluxation (AAS) is a diagnosis describing misalignment of the C1 vertebra relative to C2. Excessive translation this joint, located adjacent medullary brain stem, can lead devastating neurological consequences. A higher prevalence AAS within Down syndrome (DS) population has been well-established. This study aims establish rate DS in patients hospitalized for and compare outcomes between with without DS. Methods: utilized National Inpatient Sample (NIS)...
As the incidence of subdural hematoma is increasing, it important to understand symptomatology and clinical variables associated with treatment outcomes mortality in this population; patients were selected from National Inpatient Sample (NIS) Database between 2016 2020 using International Classification Disease 10th Edition (ICD10) codes. Moderate-to-severe identified Glasgow Coma Scale (GCS). Multivariate regression was first used identify predictors in-hospital then beta coefficients...
Abstract Postoperative aphasia is a risk inherent to resections of brain masses in language eloquent areas. Neurosurgical strategies minimize damage functional structures include awake craniotomies combined with stimulation mapping and intra-operative speech pathology (SLP) testing. Until now, consideration white matter tracts involved processing as measured by diffusion tensor imaging (DTI) has been minimally incorporated into resection planning. In addition, there limited understanding the...
Limited literature exists on the morbidity and mortality of AVM associated intracerebral hemorrhage (ICH) compared with non-AVM ICH.We examine in cAVM a large nationwide inpatient sample to create prognostic ruptured score.This retrospective cohort study from 2008 2014 compares outcomes related hemorrhages ICH utilizing National Inpatient Sample database. Diagnostic codes for underlying were identified. We case fatality according medical complications. Multivariate analysis was used derive...
Medical complications are a notable source of in-hospital death following aneurysmal subarachnoid hemorrhage (aSAH). However, there is paucity literature examining medical on national scale. This study uses dataset to analyze the incidence rates, case fatality and risk factors for mortality aSAH. We found that most common in aSAH patients (N = 170, 869) were hydrocephalus (29.3%) hyponatremia (17.3%). Cardiac arrest was cardiac complication (3.2%) associated with highest rate overall (82%)....
Current surgical scrub guidelines suggest that fingernail polish should not be worn by healthcare providers despite collective evidence demonstrating a relationship between and surgical-site infection (SSI). The purpose of this study was to determine the effect staff wearing nail on incidence SSI after caesarean delivery. In calendar block-randomised clinical trial, were assigned wear or have unpainted nails for alternating two-week periods. primary outcome site within 6 weeks There 372...
Catheter-based angiography is an essential procedure for the diagnosis and treatment of vascular complications in patients. Since cerebral coronary are similar techniques that utilize same access sites general principles, associated risks overlap should be identified to help direct patient care. The purpose this study was determine complication rates a combined cohort patients, as well conduct comparative analysis complications. National Inpatient Sample queried from 2008 2014 identify...
(1) Background: Celiac disease (CD) can cause long-term inflammation and endothelial dysfunction has been cited as a risk factor for acute ischemic stroke (AIS) in pediatric patients. However, the rate outcomes of AIS patients with CD not explored large population. Our objective is to explore rate, severity, amongst on nationwide level. (2) Methods: The National Inpatient Sample (NIS) database was queried from 2016 2020 principal diagnosis AIS. Patients concurrent (AIS-CD) were compared...
Abstract Purpose: This study aimed to investigate in-patient mortality and predictors of death associated with convulsive status epilepticus (CSE) in a large nationwide cohort. Methods: Retrospective data from the National Inpatient Sample (NIS) database between 2007 2014 were analyzed, including 123,082 adults CSE. Univariate logistic testing identified admission variables, neurological medical complications mortality. A simplified clinical prediction score, called M 3 2 S H, was generated...