- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Neurological Complications and Syndromes
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebral Venous Sinus Thrombosis
- Stroke Rehabilitation and Recovery
- Vascular Malformations Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Pharmacological Effects and Toxicity Studies
- Vascular Anomalies and Treatments
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Epilepsy research and treatment
- Takotsubo Cardiomyopathy and Associated Phenomena
- Atrial Fibrillation Management and Outcomes
- Multiple Sclerosis Research Studies
- Pneumonia and Respiratory Infections
- Long-Term Effects of COVID-19
- Cardiovascular and Diving-Related Complications
- COVID-19 and healthcare impacts
- Cannabis and Cannabinoid Research
Hartford Hospital
2018-2025
Hartford Financial Services (United States)
2019-2025
Saint Francis University
2025
Saint Francis Health System
2025
Neurosciences Institute
2025
University of Connecticut
2017-2024
University of Hartford
2017-2024
UCLA Health
2021-2024
SUNY Upstate Medical University
2020-2023
University of Mississippi Medical Center
2022-2023
Background Marijuana is a widely used recreational substance. Few cases have been reported of acute myocardial infarction following marijuana use. To our knowledge, this the first ever study analyzing lifetime odds (AMI) with use and outcomes in AMI patients versus without Methods We queried 2010-2014 National Inpatient Sample (NIS) database for 11-70-year-old patients. Pearson Chi-square test categorical variables Student T-test continuous were to compare baseline demographic hospital...
To test the hypothesis that race-, age-, and sex-specific incidence of cerebral venous thrombosis (CVT) has increased in United States over last decade.In this retrospective cohort study, validated ICD codes were used to identify all new cases CVT (n = 5,567) State Inpatients Databases (SIDs) New York Florida (2006-2016). A case was defined as first hospitalization for SID without prior hospitalization. counts combined with annual Census data compute incidence. Joinpoint regression evaluate...
IV tPA (intravenous thrombolysis with alteplase) and mechanical thrombectomy (MT) utilization increased in acute ischemic stroke hospitalizations the United States over last decade. It is uncertain whether this increase occurred equally across all age, sex, racial groups.Adult (weighted n=4 442 657) contained 2008 to 2017 National Inpatient Sample were identified using International Classification of Diseases codes. Proportions MT computed according race. Joinpoint multivariable-adjusted...
To test the hypothesis that age and sex-specific prevalence of infectious (pneumonia, sepsis, urinary tract infection [UTI]) noninfectious (deep venous thrombosis [DVT], pulmonary embolism [PE], acute renal failure [ARF], myocardial infarction [AMI], gastrointestinal bleeding [GIB]) complications increased after ischemic stroke (AIS) hospitalization in United States from 2007 to 2019.We conducted a serial cross-sectional study using 2007-2019 National Inpatient Sample. Primary AIS admissions...
Arrhythmias have been one of the common complications in epilepsy patients and also reason for death. However, limited data exist about burden outcomes arrhythmias by subtypes epilepsy. Our study aims at evaluating differences various patient population. The Nationwide Inpatient Sample (NIS) database from 2014 was examined related discharges using appropriate International Classification Disease, Ninth Revision Clinical Modification (ICD-9-CM) codes. frequency arrhythmias, gender arrhythmia...
<h3>Background and Objective</h3> To test the hypothesis that age-specific, sex-specific, race-specific ethnicity-specific incidence of nontraumatic subarachnoid hemorrhage (SAH) increased in United States over last decade. <h3>Methods</h3> In this retrospective cohort study, validated International Classification Diseases codes were used to identify all new cases SAH (n = 39,475) State Inpatients Databases New York Florida (2007–2017). counts combined with Census data calculate incidence....
Poor aqueous solubility besides extensive hepatic first effect significantly decreases the oral absorption of levosulpiride, which in turn minimizes its therapeutic effectiveness. Niosomes have been extensively investigated as a transdermal vesicular nanocarrier to increase delivery low permeable compounds into and across skin. This research work was design, develop optimize levosulpiride-loaded niosomal gel evaluate prospects for delivery. The Box-Behnken design used niosomes by analyzing...
BACKGROUND Rescue intracranial stenting (RICS) is increasingly recognized as a potentially effective rescue strategy following failed mechanical thrombectomy (MT) for large vessel occlusion due to atherosclerosis, but population‐level data on contemporary patterns of RICS utilization in MT are lacking. The aim this study describe trends the United States last decade. METHODS We conducted serial cross‐sectional using all primary acute ischemic stroke (AIS) admissions with 2010–2020 National...
Infectious intracranial aneurysms (IIAs), a notable complication of infective endocarditis (IE), pose significant clinical challenges. This study delineates the outcomes, management strategies, and manifestations IIAs, drawing from single-center's experience. We conducted retrospective observational analysis at our institution, focusing on patients diagnosed with IE between 2016 2022 who were also found to have IIAs. Data was performed utilizing SAS statistical software alongside Microsoft...
Purpose This study aimed to investigate in-patient mortality and predictors of death associated with convulsive status epilepticus (CSE) in a large nationwide cohort create simplified predictive score for in-hospital mortality. Methods Retrospective data from the National Inpatient Sample (NIS) database between 2007 2014 were analyzed, including 123,082 adults CSE. Univariate logistic testing identified admission variables, neurological medical complications A clinical prediction score,...
Background Functional outcomes in elderly thrombectomy patients have been commonly reported up to 90 days, though long-term neurological status is not as well characterized. We studied 1-year ≥ 80 years old and identified predictors of functional independence patients. Methods Retrospective analysis anterior circulation presenting from November 2016-August 2023 a large health system. The primary outcome was modified Rankin Scale score (mRS) 0–2. Outcomes were compared between < old....
Background Recent trends in the legalization of marijuana many states are increasing popularity recreational use. Since current data on hospitalizations users is sparse, we evaluated primary reasons for admissions, procedures and associated healthcare burden hospitalized users. Methods The National Inpatient Sample (NIS) years 2010-2014 was queried with a history usage using applicable ICD-9 CM codes. Descriptive statistics were used to report frequency (N) percentage (%). Discharge weights...
Vascular imaging is an essential tool to appropriately diagnose and treat intracranial saccular aneurysms. There extensive heterogeneity in aneurysm characteristics including location, size, shape, patient demographics, clinical status that leads a great diversity both surgical endovascular treatment options. This variability may elicit confusion when deciding the most appropriate paradigm for individual at particular time points. A collection of pre‐ posttreatment scales grades exist, but...
Recent legalization of therapeutic and recreational cannabis use makes it imperative to have an insight into odds trends in young-onset stroke-related hospitalizations among users (18-49 years).The National Inpatient Sample dataset (2007-2014) was utilized assess national trends, hospitalizations, outcomes vs. nonusers using provided discharge weights, strata, cluster design. The rates are described per 100,000 non-users.A total 3,307,310 were identified young adults with current or previous...
Pulmonary arteriovenous fistulas (PAVFs) are a treatable cause of acute ischemic stroke (AIS), not mentioned in current American Heart/Stroke Association guidelines. PAVFs recognized as an important complication hereditary hemorrhagic telangiectasia.The prevalence PAVF and telangiectasia among patients admitted with AIS the United States (2005-2014) was retrospectively studied, utilizing Nationwide Inpatient Sample database. Clinical factors, morbidity, mortality, management were compared...
As hospitals rapidly implement mechanical thrombectomy (MT) into stroke protocols following the pivotal trials in 2015, access to and outcomes from MT may be poorer for weekend-admitted patients. We sought investigate whether a "weekend effect" influences nationally.We identified patients 2010-2014 (pre-trials) 2015-2017 (posttrials) using Nationwide Readmissions Database. On multivariate analyses, we determined factors independently associated with receiving MT. Among patients, then weekend...