Tracy Green

ORCID: 0000-0002-7198-2828
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About
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Research Areas
  • Breast Cancer Treatment Studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Cancer Cells and Metastasis
  • Advanced Breast Cancer Therapies
  • Global Cancer Incidence and Screening

NIHR Clinical Research Network
2021-2022

Chemotherapy improves outcomes for high risk early breast cancer (EBC) patients but is infrequently offered to older individuals. This study determined if there are fit with high-risk disease who may benefit from chemotherapy.A multicentre, prospective, observational was performed determine chemotherapy (±trastuzumab) usage and survival quality-of-life in EBC aged ≥70 years. Propensity score-matching adjusted variation baseline age, fitness tumour stage.Three thousands four hundred sixteen...

10.1038/s41416-021-01388-9 article EN cc-by British Journal of Cancer 2021-05-10

Background In breast cancer management, age-related practice variation is widespread, with older women having lower rates of surgery and chemotherapy than younger women, based on the premise reduced treatment tolerance benefit. This may contribute to inferior outcomes. There are currently no age- fitness-stratified guidelines which base recommendations. Aim We aimed optimise choice outcomes for (aged ≥ 70 years) operable cancer. Objectives Our objectives were (1) determine age, comorbidity,...

10.3310/xzoe2552 article EN publisher-specific-oa Programme Grants for Applied Research 2022-06-01
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