A5056026025- EEG and Brain-Computer Interfaces
- Neurobiology of Language and Bilingualism
- Transcranial Magnetic Stimulation Studies
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Management of metastatic bone disease
- Spinal Fractures and Fixation Techniques
- Functional Brain Connectivity Studies
- Spine and Intervertebral Disc Pathology
- Peripheral Nerve Disorders
- Meningioma and schwannoma management
The University of Texas MD Anderson Cancer Center
2022-2024
Carbon-fiber reinforced polyetheretherketone (CFRP)-based spinal implants are an alternative to titanium, offering less image artifact as their metallic counterparts while maintaining similar biomechanical and biocompatibility properties. Its use in the management of tumors has been reported, however perceived advantages related improved imaging quality, radiation treatment planning, detection tumor recurrence have not fully assessed.We performed a retrospective review medical records...
INTRODUCTION: DCS is the gold standard of intraoperative functional language mapping but in predicting functions and post-surgical outcomes. Moreover, can induce seizure with prolonged usage. METHODS: Eleven subjects underwent either temporal (eight) or frontal (three) lobe tumor resection surgeries involving awake using a 4x8 ECoG electrode grid (2.3mm contact exposure 10mm pitch). A MATLAB/Simulink based real-time software system running on portable laptop computer was used to map...
Surgeons must optimize the onco-functional balance by maximizing extent of resection and minimizing postoperative neurological morbidity. Optimal patient selection surgical planning requires preoperative identification nonresectable structures. Transcranial magnetic stimulation is a method noninvasively mapping cortical representations speech motor systems. Despite recent promising data, its clinical relevance appropriate role in comprehensive approach remains unknown. In this study, we aim...
Many studies have established a link between extent of resection and survival in patients with gliomas. Surgeons must optimize the oncofunctional balance by maximizing minimizing postoperative neurological morbidity. Preoperative functional imaging modalities are important tools for optimizing balance. Transcranial magnetic stimulation (TMS) resonance (fMRI) non-invasive that can be used preoperative language mapping. Scarce data exist evaluating accuracy these mapping compared gold standard...
Abstract BACKGROUND As an adjunct to direct electrical stimulation (DES), intraoperative electrocorticography (ECoG) can aid detection of language-eloquent cortex. However, it is unclear how surgical impact upon mapping findings relates cognitive-linguistic outcomes. METHODS Ten patients underwent awake craniotomy for tumor resection with ECoG and DES language mapping. Mapping utilized iPad stimulus presentation coupled electrode array capable both recording activity delivering DES....
Abstract BACKGROUND Few studies have examined concordance between intraoperative electrocorticography (ECoG) and direct electrical stimulation (DES) language mapping, especially across varied naming tasks. METHODS Twelve patients (Mdn age=59; 75% HGG) underwent awake craniotomy with ECoG DES mapping. Mapping utilized iPad stimulus presentation coupled to a 4x8 electrode array for both DES. Time-frequency gamma band activity (Early Late) was visualized 3 paradigms (Object, Action, Auditory)....
Abstract Background Electrocorticography (ECoG) language mapping is often performed extraoperatively, frequently involves offline processing, and relationships with direct cortical stimulation (DCS) remain variable. We sought to determine the feasibility preliminary utility of an intraoperative approach guided by real-time visualization electrocorticograms. Methods A patient astrocytoma underwent awake craniotomy mapping, utilizing a dual iPad stimulus presentation system coupled neural...
In patients with perieloquent tumors, neurosurgeons must use a variety of techniques to maximize survival while minimizing postoperative neurological morbidity. Recent publications have shown that conventional anatomical features may not always predict deficits. Additionally, scientific conceptualizations complex brain function shifted toward more dynamic, neuroplastic theories instead traditional static, localizationist models. Functional imaging emerged as potential tools incorporate these...
For patients with brain tumors, maximizing the extent of resection while minimizing postoperative neurological morbidity requires accurate preoperative identification eloquent structures. Recent studies have provided evidence that anatomy may not always predict eloquence. In this study, we directly compare transcranial magnetic stimulation (TMS) data combined tractography to traditional anatomic grading criteria for predicting permanent deficits in motor gliomas.We selected a cohort 42...
Abstract OBJECTIVE Determine the feasibility and preliminary utility of a novel approach to intraoperative brain mapping guided by visualization electrocorticography (ECoG) heat maps. METHODS A 39-year-old male with biopsy-proven left posterior temporal occipital WHO grade II IDH-mutant astrocytoma underwent awake craniotomy language mapping. Language utilized dual iPad stimulus presentation system (NeuroMapper) coupled portable real-time neural signal processing capable both recording...
Robust preoperative imaging can improve the extent of resection in patients with brain tumors while minimizing postoperative neurological morbidity. Both structural and functional techniques provide helpful information. A recent study found that transcranial magnetic stimulation (TMS) tractography has significant predictive value for permanent deficits. The present directly compares TMS task-based MRI (fMRI) same cohort glioma patients.Clinical outcome data were collected from charts motor...
Spinal reconstruction after resection of invasive craniocervical junction malignancies is fraught with technical and management considerations as well a paucity data in the existing literature. In this study, we describe our experience malignancies, especially influence radiation on need for revision spinal instrumentation.We performed retrospective chart review all patients who underwent occipitocervical fixation between 2011 2019 at The University Texas MD Anderson Cancer...
Abstract OBJECTIVE Determination of the correlation between gamma-band modulations electrocorticogram (ECoG) induced by linguistic tasks and reproducible speech arrests caused bipolar direct cortical stimulations (DCS). METHODS 3 subjects (age 39, 56, 64 years) with left temporal lobe glioma underwent surgery involving awake craniotomy. A 4x8 ECoG electrode grid (2.3mm contact exposure, 1cm spacing) was placed above respective tumor area. MATLAB-Simulink based real-time software system...