A5052770525- Neurological disorders and treatments
- Meningioma and schwannoma management
- Obsessive-Compulsive Spectrum Disorders
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Autism Spectrum Disorder Research
- Bone Tumor Diagnosis and Treatments
- Epilepsy research and treatment
- Glioma Diagnosis and Treatment
- Botulinum Toxin and Related Neurological Disorders
- Neurofibromatosis and Schwannoma Cases
- Brain Metastases and Treatment
- Cerebral Venous Sinus Thrombosis
- Head and Neck Surgical Oncology
- Pituitary Gland Disorders and Treatments
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- Transcranial Magnetic Stimulation Studies
- Spinal Hematomas and Complications
- Gun Ownership and Violence Research
- Neural and Behavioral Psychology Studies
- Vascular Malformations Diagnosis and Treatment
- Genetic Neurodegenerative Diseases
- Sarcoma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
Harvard University
2025
Brigham and Women's Hospital
2025
Baylor College of Medicine
2020-2024
University of Pittsburgh
2023-2024
Utrecht University
2023-2024
Analysis Group (United States)
2024
University of South Florida
2024
Texas Medical Center
2023
Texas Children's Hospital
2022
The University of Texas MD Anderson Cancer Center
2019-2022
OBJECTIVE Stereoelectroencephalography (sEEG) is a well-established surgical method for defining the epileptogenic network. Traditionally reserved identifying discrete cortical regions resection or ablation, sEEG in current practice also used more broadly involved subcortical epileptic network components, driven by availability of brain-based neuromodulation strategies. In particular, investigations including thalamic nuclei are becoming frequent parallel with increase therapeutic strategies...
A number of stereotactic platforms are available for performing deep brain stimulation (DBS) lead implantation. Robot-assisted stereotaxy has emerged more recently demonstrating comparable accuracy and shorter operating room times compared with conventional frame-based systems.To compare the our streamlined robotic DBS workflow data in literature from frameless systems.We retrospectively reviewed 126 consecutive placement procedures using a platform. Indications included Parkinson disease (n...
Abstract The rewards that we get from our choices and actions can have a major influence on future behavior. Understanding how reward biasing of behavior is implemented in the brain important for many reasons, including fact diminution hallmark clinical depression. We hypothesized mediated by anterior cingulate cortex (ACC), cortical hub region associated with integration executive control etiology To test this hypothesis, recorded neural activity during biased judgment task patients...
Acute spinal cord injury (SCI) is devastating for patients and their caretakers has an annual incidence of 20–50 per million people. Following initial assessment with appropriate physical examination imaging, who are deemed surgical candidates should undergo decompression stabilization. Earlier intervention can improve neurological recovery in the post-operative period while allowing earlier mobilization. Optimized medical management paramount to outcomes. Emerging strategies managing SCI...
OBJECTIVE Vestibular schwannomas (VSs) are the most common neoplasm of cerebellopontine angle in adults. Though these lesions generally slow growing, their growth patterns and associated symptoms can be unpredictable, which may complicate decision to pursue conservative management versus active intervention. Additionally, surgical decision-making controversial because limited high-quality evidence multiple quality-of-life considerations. Machine learning (ML) is a powerful tool that utilizes...
Deep brain stimulation (DBS) for Parkinson disease (PD) is traditionally performed with awake intraoperative testing and/or microelectrode recording. Recently, however, the procedure has been increasingly under general anesthesia image-based verification. The authors sought to compare structural and functional networks engaged by asleep PD-DBS of subthalamic nucleus (STN) correlate them clinical outcomes.Levodopa equivalent daily dose (LEDD), pre- postoperative motor scores on Movement...
Repeat craniotomy in patients with primary and metastatic brain tumors carries significant morbidity can delay adjuvant treatments. laser interstitial thermal therapy (LITT) for recurrent disease has been described could benefit limited cytoreductive options. We aim to describe the indications, safety, efficacy of repeat LITT intracranial tumors.Patients undergoing ablations same lesion were included study. retrospectively analyzed 13 treated 29 total ablations.Eleven glioblastoma (GBM),...
Meningiomas are the most common primary intracranial tumor. Seizures sequelae of meningioma development. Meningioma patients with seizures can be effectively treated resection, reports seizure freedom 60%-90%. Still, many manifest persistent epilepsy. Determining factors associated worsened outcomes remains critical in improving quality life for these patients. The authors sought to identify clinical, radiological, and histological worse supratentorial preoperative seizures.
Surgeons must optimize the onco-functional balance by maximizing extent of resection and minimizing postoperative neurological morbidity. Optimal patient selection surgical planning requires preoperative identification nonresectable structures. Transcranial magnetic stimulation is a method noninvasively mapping cortical representations speech motor systems. Despite recent promising data, its clinical relevance appropriate role in comprehensive approach remains unknown. In this study, we aim...
Large arachnoid granulations that protrude into dural venous sinuses and partially obstruct outflow are an underappreciated etiology of pulsatile tinnitus (PT). Endovascular sinus stenting is thought to diminish turbulent may relieve obstruction caused by granulations.Four patients at two institutions were evaluated for unilateral PT. Magnetic resonance imaging digital subtraction angiography revealed moderate-to-severe stenoses from large within the implicated transverse sinus. All...
Magnetoencephalography (MEG) is a useful component of the presurgical evaluation patients with epilepsy. Due to its high spatiotemporal resolution, MEG often provides additional information clinician when forming hypotheses about epileptogenic zone (EZ). Because increasing utilization stereo-electroencephalography (sEEG), clusters are used guide sEEG electrode targeting frequency. However, there no predefined features an cluster that predict ictal activity. This study aims determine which...
Deep brain stimulation (DBS) is an accepted therapy for severe, treatment-refractory obsessive-compulsive disorder (trOCD). The optimal DBS target location within the anterior limb of internal capsule, particularly along anterior-posterior axis, remains elusive. Empirical evidence from several studies in past decade has suggested that ideal lies vicinity commissure (AC), either just to AC, above ventral striatum (VS), or posterior bed nucleus stria terminalis (BNST). Various methods have...
Dural arteriovenous fistulas (dAVFs) are vascular abnormalities of the central nervous system that can cause a wide array neurological dysfunction depending on their location, flow, and propensity to rupture. Symptomatic dAVFs at cranio-cervical junction usually result in hemorrhage or cervical myelopathy. Distantly located foramen magnum rare thoracic intrinsic myelopathy.An 83-yr-old man presented with progressive lower extremity weakness, numbness, difficulty walking along episodes bowel...
BACKGROUND: Meningiomas are the most common intracranial neoplasms. Although genomic analysis has helped elucidate differences in survival, there is evidence that racial disparities may influence outcomes. African Americans have a higher incidence of meningiomas and poorer survival The etiology these remains unclear, but include combination pathophysiology other factors. OBJECTIVE: To determine factors contribute to different clinical outcomes populations. METHODS: We retrospectively...
Background: Myeloid sarcoma (MS), or chloroma, is a rare extramedullary malignant tumor that consists of undifferentiated granulocytic cells, and it most commonly associated with acute myeloid leukemia (AML). Intracranial MS accounts for 0.4% cases, involvement the skull base visual dysfunction rarely reported. However, optimal treatment response to in presence symptoms unknown. Case Description: A 30-year-old male history AML presented rapidly progressive vision loss sellar parasellar mass...