A5037099536- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Chemotherapy-induced organ toxicity mitigation
- Trace Elements in Health
- Chronic Myeloid Leukemia Treatments
- Vitamin D Research Studies
- Acute Myeloid Leukemia Research
- Acute Lymphoblastic Leukemia research
- Gastric Cancer Management and Outcomes
- Lymphoma Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Chronic Lymphocytic Leukemia Research
- Optimism, Hope, and Well-being
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Hepatitis C virus research
- Rheumatoid Arthritis Research and Therapies
- Adipokines, Inflammation, and Metabolic Diseases
- Nutrition, Genetics, and Disease
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Lung Cancer Treatments and Mutations
- Eosinophilic Disorders and Syndromes
- Glutathione Transferases and Polymorphisms
- Platelet Disorders and Treatments
Islamic Azad University of Najafabad
2025
Zahedan University of Medical Sciences
2013-2024
Shahid Bahonar University of Kerman
2022
Fas/Fas ligand (FasL) system is one of the key apoptotic signaling entities in extrinsic pathway. De-regulation this pathway, i.e. by mutations may prevent immune from removal newly-formed tumor cells, and thus lead to formation. The present study investigated association between -1377 G/A (rs2234767) -670 A/G (rs1800682) polymorphisms Fas as well single nucleotide INV2nt -124 (rs5030772) -844 C/T (rs763110) FasL a sample Iranian patients with breast cancer. This case-control was done on 134...
Aim: Our study aimed to evaluate the possible association between four miRNA polymorphisms, hsa-miR-146a (rs2910164 G>C), hsa-miR-499 (rs3746444 T>C) and hsa-miRNA-196a2 (rs11614913 C>T rs185070757 T>G), susceptibility breast cancer in an Iranian population. Materials & methods: In this case–control we enrolled 236 patients with 203 healthy individuals. Tetra primer amplification refractory mutation system PCR was applied for genotyping SNPs. Results: indicated that hsa-mir-499 rs3746444 CC...
Human leukocyte antigen G (HLA-G) is a non-classic major histocompatibility complex (MHC) class I molecule that highly expressed in cancer pathologies. A 14-bp insertion/deletion polymorphism exon 8 of the 3' untranslated region (3'-UTR)
Hypereosinophilic syndrome (HES) is traditionally described as chronic peripheral eosinophilia with involvement of various organs and systems, including the heart nervous system.In this report, we describe cardiac border zone stroke in a patient idiopathic HES.A 37-year-old woman presented sudden right-sided weakness slurred speech, which began four days before admission, accompanied by palpitations, retrosternal exertional chest discomfort, dry cough, progressive shortness breath over...
Background . Although uremic pruritus is a common and upsetting problem of chronic kidney disease, there no approved treatment for it. This study was undertaken to find the efficiency sertraline as possible pruritus. Methods 19 ESRD patients under hemodialysis with severe were randomly selected participate in this before-after clinical trial. Before after starting sertraline, detailed history obtained graded by 30-item inventory that based on priorities grade allocated 3 classes. Subjects...
Genetic and environmental factors are risk for breast cancer. Our aim was to investigate the associations between genetic polymorphism of GST genes (GSTM1, GSTT1 GSTP1) susceptibility cancer in an Iranian population.This case-control study carried out on 134 patients with 152 healthy, cancer-free women. GSTP1 determined using tetra-primer amplification refractory mutation system PCR assay GSTM1 were genotyped by a multiplex PCR.We found that null genotype is factor predisposition (odds ratio...
Breast cancer (BC) is one of the most causes death in women worldwide. It affects Iranian female population approximately a decade earlier than those other parts world. Previous studies have shown that vascular endothelial growth factor (VEGF) gene variants were associated with BC risk. The current study aimed to evaluate impact VEGF rs3025039 (+936C>T), rs2010963 (+405C>G), rs833061 (–460T>C), rs699947 (–2578C>A), and rs35569394 (18-bp I/D) polymorphisms on risk an southeast...
Aim: MicroRNAs (miRNAs) are small noncoding RNAs that function as oncogene or tumor suppressors. The single nucleotide polymorphisms in miRNAs potentially can alter miRNA-binding sites on target genes well affecting expression. present study aimed to evaluate the impact of miR-608 rs4919510 C>G variant breast cancer (BC) risk. Materials and Me thods: This case-control conducted 160 women with BC 192 age-matched healthy women. Genotyping miR608 was done using polymerase chain...
Abstract Introduction Rheumatoid Arthritis ( RA ) is one of the most prevalent autoimmune diseases. Due to significance relationship between serum vitamin D levels and diseases, this study aimed determine level severity disease activity in patients with newly diagnosed . Method This cross‐sectional was conducted on 66 meeting A merican C ollege R heumatology – E uropean L eague gainst heumatism classification criteria for It performed 2012 using simple sampling. The measured based isease...
There are different and controversial reports about zinc deficiency in patients with major thalassemia.The aim of this study was to evaluate status thalassemia Sistan Baluchistan province, southeastern Iran.The performed Ali Asghar Hospital, a specialized governmental hospital located Zahedan, Iran. In cross-sectional study, 369 history for more than 5 years entered the using convenience sampling method. Thirty-six subjects were excluded from based on our exclusion criteria. Zinc level...
Background: Recent evidence has demonstrated the implication of CC chemokine ligand 5 (CCL5) and receptor (CCR5) in breast tumor initiation progression. Objective: The purpose this study was to investigate whether single nucleot
Objective: In recent decades, the incidence of thyroid cancer has increased throughout world. It is unclear whether factors such as vitamin D deficiency may have been involved in this increase. The present case-control study was conducted to examine any association between Vitamin and cancers. Methods: on 85 patients with differentiated diagnosed based fine needle aspiration biopsy case group healthy controls. Serum levels were evaluated before thyroidectomy. For each patient group, one...
Background: There are different controversial reports about Zinc status in healthy and normal population. The aim of this study is to evaluate Methods: This cross-sectional conducted on 320 subjects aged between 10 - 30 years without any underlying diseases or history mineral therapy Zahedan, south east Iran. level was measured all after 12 hours fasting. All blood samples were centrifuged following 45 minutes spontaneous coagulation then stored at -20°C. using graphite furnace atomic...