Fangming Guo

ORCID: 0000-0002-7226-9450
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About
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Research Areas
  • Acute Myocardial Infarction Research
  • Coronary Interventions and Diagnostics
  • Cardiac Ischemia and Reperfusion
  • Cardiac Imaging and Diagnostics
  • Neuroscience of respiration and sleep
  • Regulation of Appetite and Obesity
  • Sleep and Wakefulness Research
  • Venous Thromboembolism Diagnosis and Management
  • Robotics and Automated Systems
  • Hormonal and reproductive studies
  • Nausea and vomiting management
  • Estrogen and related hormone effects
  • Blood Coagulation and Thrombosis Mechanisms
  • Peptidase Inhibition and Analysis
  • Advanced X-ray and CT Imaging
  • Neural Networks and Applications
  • Medical Research and Treatments
  • Medical Imaging and Analysis
  • Cardiac Fibrosis and Remodeling
  • Adenosine and Purinergic Signaling
  • Cardiac Arrest and Resuscitation
  • Cardiac, Anesthesia and Surgical Outcomes
  • Menopause: Health Impacts and Treatments
  • Plant-based Medicinal Research
  • Pathogenesis and Treatment of Hiccups

Chongqing University
2024

Binzhou Medical University
2022

Yantaishan Hospital
2012-2022

Binzhou University
2022

Qingdao University
2011-2017

Second Hospital of Tianjin Medical University
2009-2010

Tianjin Medical University
2009-2010

We hypothesized that flow-mediated vasodilation (FMD) in the brachial artery as a noninvasive method is of value providing further predictive insights cohort patients with ST-segment elevation acute myocardial infarction (STEMI) after percutaneous coronary intervention (PCI).One hundred and one (62.43+/-9.06, 67 men) STEMI, undergoing successful primary rescue PCI, were included this study. FMDs all determined using ultrasound PCI. Patients tracked for subsequent cardiovascular events....

10.1097/mca.0b013e32832e5c61 article EN Coronary Artery Disease 2009-10-22

Nowadays, chemotherapy induced nausea and vomiting (CINV) is still common in patients with cancer. It was reported that substance P mediated CINV via neurokinin-1 (NK1 ) receptor antagonists of NK1 has been proved useful for treating but the mechanism are not fully understood. This study aimed to examine role blocker, CP-99 994, when administrated into dorsal motor nucleus vagus (DMNV), on cisplatin-induced emesis rats possible mechanism.Rats' kaolin intake, food bodyweight were recorded...

10.1111/nmo.13096 article EN Neurogastroenterology & Motility 2017-05-02

Shenfu injection (SFI) is commonly used for cardiac dysfunction in China. Adenosine receptors have been reported to exert anti-fibrosis effects. The intent of this study was evaluate that SFI attenuates fibrosis through activating adenosine A2a receptor (A2aR) rats with myocardial ischemia-reperfusion (MI/R).Sprague Dawley male were randomly divided into five groups, nine each group. Injections all rat groups carried out prior reperfusion, and the sham MI/R only vehicle injected. remaining...

10.1177/09603271221077684 article EN cc-by-nc Human & Experimental Toxicology 2022-01-01

Background Intestinal motilin is known to stimulate gastrointestinal (GI) motility and the arcuate nucleus (Arc) of hypothalamus shown be involved in regulation GI motility. Methods Single unit discharges Arc were recorded extracellularly by implantation a force transducer into stomach rats, evaluate effect on gastric Projection nerve fiber expression observed retrograde tracer deposits Fluoro-Gold (FG) fluo-immunohistochemistry staining. Key Results 65.5% neurons responded distension (GD),...

10.1111/j.1365-2982.2010.01661.x article EN Neurogastroenterology & Motility 2011-02-08

The aim of the present study was to evaluate use preoperative high-dose atorvastatin prevent no-reflow phenomenon after percutaneous coronary intervention (PCI). A total 138 patients with ST‑segment elevation myocardial infarction, admitted from March 2014 January 2015, were enrolled and randomly divided into 3 groups 46 individuals each. included a control group in which not treated before PCI; conventional‑dose treatment received single dose 20 mg at bedtime one day prior 40 two doses PCI....

10.3892/etm.2016.3910 article EN Experimental and Therapeutic Medicine 2016-11-18

Motilin, an important endocrine regulator of gastrointestinal motility, was once considered to be produced in the tract and brain. In recent years, however, motilin has been found human thyroid, as well that guinea pig. The physiological function central modulation thyroidal remain poorly understood. To determine functional role motilin, we observed concentration plasma also gastric motility before after thyroidectomy. Our studies show both were decreased explore modulation-related nuclei, a...

10.1111/j.1365-2826.2011.02190.x article EN Journal of Neuroendocrinology 2011-07-14

Shenfu injection (SFI) has been reported to have a protection against myocardial ischemia-reperfusion (MI/R) injury. However, the changes of adenosine receptors in MI/R postconditioning when pretreated with SFI are unclear.Forty-five rats were randomly divided into sham group (sham), (MI/R-post), low-dose (1 mL/kg), middle-dose (2.5 and high-dose (5 mL/kg). In groups, was intravenously injected before reperfusion, treated ischemic after ischemia for 30 min. After 24 h levels Ca2+ cAMP blood...

10.1177/09603271211041668 article EN Human & Experimental Toxicology 2021-08-31

Objective: Atherosclerotic plaque rupture leading to coronary artery occlusion is the culprit event which underpins a majority of acute myocardial infarction, and Matrix metalloproteinases (MMPs) contribute atherosclerotic by involving in extracellular matrix degradation artificial balloon extrusion.Patients with ST-segment elevation infarction (STEMI) caused are at high risk for slow reflow, but relationship between reflow MMP-9 remains unclear, especially real world local rupture.We...

10.4172/2155-6156.1000749 article EN Journal of Diabetes & Metabolism 2017-01-01

The aim of the present study was to assess early clinical outcome and risk factors in old patients with acute ST elevation myocardial infarction (STEMI) following primary percutaneous coronary intervention (PCI). A total 136 older than 60 years STEMI who received successful PCI were included this study. classified 2 age groups: =75 <75 age. extent artery lesions measured by quantitative angiography (QCA). Subjects tracked for subsequent cardiovascular events: cardiac death, infarction, heart...

10.1016/s1000-1948(10)60014-7 article EN Journal of Medical Colleges of PLA 2010-02-01

Coronary artery disease (CAD) is one of the leading causes death and disability in developing world. Invasive coronary angiography considered golden standard diagnosis for CAD. As invasive procedures have an associated mortality (0.15%) morbidity (1.5%), cardiologists desired to find accurate noninvasive diagnostic tests. More recently, cardiac MDCT has gained popularity detection quantification disease. Cardiac fastest growing imaging modality China, with dedicated cardiovascular systems...

10.1109/itime.2009.5236441 article EN 2009-08-01

Objective To explore the ischemic postconditioning effects on heart failure after acute myocardial infarction. Methods There were 200 infarction patients within 12 h emergency PCI, of which 100 received routine PCI therapy (control group), and other therapy(IPTC group). The parameters between two groups CK-MB, cTnI, BNP, LVEF, LVEDD by echocardiography observed. Results 3 days cTnI level control group (40.40±3.85)ng/ml was higher than that IPTC (23.12±2.36)ng/ml, difference...

10.3877/cma.j.issn.2095-655x.2018.03.009 article EN Chin J Diagnostics(Electronic Edition) 2018-08-26
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