A5070938088- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Analytical chemistry methods development
- Biosensors and Analytical Detection
- Metabolomics and Mass Spectrometry Studies
- Advanced biosensing and bioanalysis techniques
- Analytical Chemistry and Sensors
- Advanced Measurement and Detection Methods
- SARS-CoV-2 detection and testing
- Cell Image Analysis Techniques
- Single-cell and spatial transcriptomics
- Optical measurement and interference techniques
- Analytical Methods in Pharmaceuticals
- Thermography and Photoacoustic Techniques
Xiamen University
2025
Ningbo University
2021-2024
Shanghai Innovative Research Center of Traditional Chinese Medicine
2023
Extraction of micro-vibration information from a single-shot speckle image is realized base on the row-by-row exposure mechanism rolling shutter camera and high intensity laser speckle. Normalized cross correlation cubic spline interpolation algorithm firstly used between nonoverlapping gray scales adjacent rows to infer micro-displacement information. With number set as 342, wide frequency range 300 Hz 20 kHz sinusoid signals are recovered with relative errors smaller than 2%. For low 40...
<i>Objective</i>: The increasing demand for unraveling cellular heterogeneity has boosted single cell metabolomics studies. However, current analytical methods are usually labor-intensive and hampered by lack of accuracy efficiency. <i>Methods</i>: we developed a first-ever automated mass spectrometry system (named SCMS) that facilitated the metabolic profiling cells. In particular, extremely small droplets sub nano-liter were generated to extract cells, underlying mechanism was verified...
On-site determination of trace copper ions in natural waters is great significance to environmental monitoring, and how develop accurate specific point-of-care test methods one critical issue. In the study, a paper-based analytical device (PAD) being modified with new truncated DNAzyme (CLICK-T, which was derived from reported DNAzyme-CLICK-17) developed for Cu detection. The detection mechanism based on Cu(II)-catalyzed azide-alkyne cycloaddition (Cu(II)AAC) reaction. It can directly...
The authors make the following corrections to published paper [...]
Mass spectrometry (MS) has become an essential analytical method in every sector of science and technology. Because its unique ability to provide direct molecular structure information on analytes, extra is rarely required. This review describes fabrication a variable-pressure hollow cathode discharge (HCD) ion source for MS detection, quantification investigation gas-phase molecule reactions explosives related compounds using air as carrier gas. The HCD been designed such way that by...
According to the Report of Drug Situation in China (2020), growth rate number drug abusers has decreased, but is still large. An efficient screening method necessary for controlling abuse. As an important type biological sample, urine widely used rapid addicts. However, because complex composition, low content, and strong interference from body's metabolism, detection drugs remains a challenge. Traditional techniques such as immunocolloidal gold analysis have high false positive insufficient...
Ambient ionization mass spectrometry (AIMS) is an emerging onsite rapid detection technique that has been applied in the area of public security. AIMS measurements samples with complex matrices are characterized by poor reproducibility and complexity. Low background cause imprecise screening for trace drugs hair. In this work, a method methamphetamine hair proposed. Firstly, generalized weighted robust principal component analysis (GWRPCA) algorithm used to remove extract analytical signals....