A5101550492- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Extracellular vesicles in disease
- Immune cells in cancer
- SARS-CoV-2 detection and testing
- ECG Monitoring and Analysis
- Bladder and Urothelial Cancer Treatments
- Bioactive Compounds and Antitumor Agents
- Analytical Chemistry and Sensors
- Tryptophan and brain disorders
- Peptidase Inhibition and Analysis
- Autophagy in Disease and Therapy
- Signaling Pathways in Disease
- MicroRNA in disease regulation
- Aquaculture disease management and microbiota
- Vibrio bacteria research studies
- Polysaccharides Composition and Applications
- Cancer therapeutics and mechanisms
- Food composition and properties
- Immune Cell Function and Interaction
- Nanoparticles: synthesis and applications
- Biomarkers in Disease Mechanisms
- Immune Response and Inflammation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Nanjing Medical University
2023-2024
Ningbo University
2020-2024
China Pharmaceutical University
2022
Chongqing Medical University
2018-2021
Changhai Hospital
2021
Second Military Medical University
2021
Huazhong University of Science and Technology
2013
Wuhan Institute of Bioengineering
2013
Harvard University
1993
In EVs derived from plasma of acute coronary syndrome patients experiencing SCD, miR-208b-3p and miR-143-3p were significantly upregulated ultimately identified as reliable biomarkers for the prediction SCD.
IL-10, in addition to being a cytokine synthesis-inhibitory factor, is that exerts multiple effects on various cell types. Recombinant human migration inhibitory factor (MIF) inhibits the of monocytes as well guinea pig and murine macrophages. In addition, it has recently been shown activate monocyte-derived macrophages suppress growth and/or kill both intracellular parasites extracellular tumor targets vitro have adjuvant activity vivo. this study, we examined interactions between IL-10...
Human milk oligosaccharides (HMOs) in breast contribute to the development of neonatal microbiota and immune system. However, longitudinal studies examining HMO profiles Chinese mothers remain scarce.
Abstract Stimulator of interferon genes (STING) is an innate immune receptor activated by natural or synthetic agonists to elicit antitumoral response via type I IFNs and other inflammatory cytokines. Bacillus Calmette-Guerin (BCG) the standard care as intravesical therapy for patients with high-risk non–muscle invasive bladder cancer (NMIBC). There are limited options available NMIBC who developed BCG unresponsiveness. In this study, we characterized in vitro vivo antitumor effects E7766, a...
The purpose of this study was to investigate the effects Lactobacillus rhamnosus GG (LGG) fermentation on composition, structure, and functional properties dietary fiber (DF) in bamboo shoot. Then, we added it bread evaluate texture properties, digestive functionality bread. After LGG fermentation, DF decomposed into pieces, which had stronger water-swelling capacity nitrite adsorption capacity. ability producing short-chain fatty acids significantly improved resistance remarkable enhanced...
Abstract Psychosocial stress is a vital factor contributing to the pathogenesis and progression of inflammatory bowel disease (IBD). The contribution intestinal macrophage autophagy onset development IBD has been widely studied. Herein, we investigated underlying mechanism psychosocial in an mouse model pertaining autophagy. Corticotropin releasing hormone (CRH) was peripherally administrated induce stress. For vivo studies, dextran sulfate sodium (DSS) used for creation our model. vitro...
On-site determination of trace copper ions in natural waters is great significance to environmental monitoring, and how develop accurate specific point-of-care test methods one critical issue. In the study, a paper-based analytical device (PAD) being modified with new truncated DNAzyme (CLICK-T, which was derived from reported DNAzyme-CLICK-17) developed for Cu detection. The detection mechanism based on Cu(II)-catalyzed azide-alkyne cycloaddition (Cu(II)AAC) reaction. It can directly...
Abstract Pentraxin-3 (PTX-3) is one of the newly discovered tumor biomarker, especially in diagnosis lung cancer. The functionalized multi-walled carbon nanotubes (MWCNTs) and gold nanowires (AuNWs) nanocomposites decorated PTX-3 biosensor were reported this work, realizing ultrasensitive detection human serum through simple effective non-enzymatic reaction. has excellent electrochemical activity biocompatibility metal nanomaterials. Compared with pure MWCNTs, MWCNTs combined AuNWs which...
The authors make the following corrections to published paper [...]
Identification of sudden cardiac death (SCD) with a structurally normal heart remains an important challenge in forensic pathology. Long QT syndrome (LQTS) is known as inherited or acquired channelopathy, which characterized prolonged interval, and likely to cause SCD young adults. In this circumstance, no specific pathological change the can be found anatomically histologically LQTS victims. Thus, postmortem diagnosis mainly based on clinical manifestations genetic testing. Here, we...
Abstract Background & Aim: Exosomes are effective mediators of cell-to-cell interactions and carry many regulatory molecules, including miRNAs, that can play crucial roles in diverse fundamental biological processes. However, to date, no study has reported macrophage exosomal involvement the development inflammatory bowel disease (IBD). This investigated specific miRNAs macrophage-derived exosomes IBD potential molecular mechanism. Methods: Dextran sulfate sodium (DSS) was used generate...