A5011295214- Cardiovascular Function and Risk Factors
- Exercise and Physiological Responses
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Disease and Adiposity
- Hydrogen's biological and therapeutic effects
- High Altitude and Hypoxia
- Cardiovascular Health and Disease Prevention
- Adipose Tissue and Metabolism
- Muscle metabolism and nutrition
- Cardiac Imaging and Diagnostics
- Cardiovascular and exercise physiology
- Vitamin D Research Studies
- Clinical Nutrition and Gastroenterology
- Acute Kidney Injury Research
- Obesity, Physical Activity, Diet
- Alcohol Consumption and Health Effects
- Genetics and Physical Performance
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular and Diving-Related Complications
- Adipokines, Inflammation, and Metabolic Diseases
- Chronic Kidney Disease and Diabetes
- Thermoregulation and physiological responses
- Nutrition and Health in Aging
- Diet and metabolism studies
- Sports and Physical Education Research
University of Tokyo Hospital
2023
The University of Tokyo
2014-2021
Yamanashi Gakuin University
2021
University of Yamanashi
2003-2020
Tokoha Gakuen University
2016
Waseda University
2016
Rakuno Gakuen University
2016
Uganda Episcopal Conference
2016
Hyogo Medical University
1997
Abstract Background Insulin resistance carries increased risk of heart failure, although the pathophysiological mechanisms remain unclear. LV global longitudinal strain (LVGLS) assessed by speckle-tracking echocardiography has emerged as an important tool to detect early systolic abnormalities. This study aimed investigate association between insulin and subclinical left ventricular (LV) dysfunction in a sample general population without overt cardiac disease. Methods We investigated 539...
Repeated sprint exercise can interfere with intramuscular redox balance and cause systemic oxidative stress muscle damage. There is growing evidence that molecular hydrogen counteracts and/or inflammatory responses. Therefore, we investigated the effects of hydrogen-rich water (HW) on performance markers induced by strenuous exercise. A single-blind, crossover, randomized controlled trial has been designed. Eight male volunteers completed two 3-day consecutive tests under conditions: HW...
Molecular hydrogen has been suggested to have a cytoprotective effect on the whole body and enhance exercise performances. However, of hydrogen-rich gas mixture (HG) inhalation physiological responses poorly investigated. We examined impact acute HG subsequent oxidative stress, muscle damage, performances during recovery period after strenuous exercise. This is two-trial, double-blind, crossover, repeated measures study. Eight physically active male volunteers inhaled (estimated fraction...
Arterial structural and functional remodeling is recognized as a key determinant of incident heart failure, although the contribution arterial properties on left ventricular (LV) not fully studied. Aortic dilatation an early manifestation estimated pulse wave velocity (ePWV) emerging simple measure stiffness. This study aimed to characterize association aortic size ePWV with LV morphology function.The cohort consisted 539 participants without overt cardiac disease who underwent extensive...
Aims] Skyrunning (SR) is an extreme sport of mountain running above 2,000 meters, and the number participants in SR rapidly increasing Europe.In Japan, has been growing popularity since establishment Japan Association (JSA) 2013.However, physical loads during remain unknown.The purpose this study was to examine effects on runners.[Methods] 7 healthy males females performed skyrunning (from 1,500 m 2700 altitude) followed by a pre-test (20 shuttle-run, weight bearing index, vertical jump,...
Abstract Aims Emerging evidence suggests an association between non-alcoholic fatty liver disease (NAFLD) and heart failure (HF). We investigated the relationship NAFLD left ventricular (LV) functional remodelling in a general population sample without overt cardiac disease. Methods results included 481 individuals significant alcohol consumption who voluntarily underwent extensive cardiovascular health check. The index (FLI) was calculated for each participant, defined as FLI ≥ 60. All...
PURPOSE: Recently, it is going noteworthy that an exercise-induced novel myokine, secreted protein acidic and rich in cysteine (SPARC) has the potential to prevent colon cancer. Moreover, regular resistance exercise (RE) been known reduce mortality risk of From these points view, RE might tumorigenesis via increasing SPARC, while unclear whether can promote SPARC secretion human. Thus, purpose this study was investigate both effects intensity duration rest interval between sets on acute...
Abstract Background Obesity carries independent risk for incident atrial fibrillation (AF), although the impact of abdominal fat distribution on LA morphological and functional remodeling is not fully elucidated. Speckle-tracking echocardiography a novel sensitive tool that allows quantification detection subtle alterations in left (LA) phasic function. Purpose This study aimed to investigate whether increased visceral adiposity independently associated with impaired function community-based...
Severe exercise is generally known to induce oxidative stress. A number of makers predict the stress such as thiobarbituric acid reactive substances (TBARS) and glutathione are evaluated in various tissues. Recent reports also suggest that DNA injury occurs by exercise-induced disturbance redox status. To date, training considered up-regulation antioxidant enzymes, which prevent extensive cellular damage. However, effect regular on damage after an acute exhaustive remains be examined humans....
2021.—Many previous studies have examined hypoxia-induced physiological responses using various conditions, e.g., artificially reduced atmospheric oxygen concentration [normobaric hypoxia (NH) condition] or low barometric pressure at a mountain [hypobaric (HH) condition]. However, when comparing the results from these conducted in artificial NH and HH including real high altitude, we must consider possibility that environmental factors, such as temperature, humidity, fraction of inspired...