Melanie R. F. Gropler

ORCID: 0000-0002-7254-7844
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About
Contact & Profiles
Research Areas
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Tracheal and airway disorders
  • Congenital Heart Disease Studies
  • Systemic Lupus Erythematosus Research
  • Pregnancy and Medication Impact
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Issues in Pregnancy
  • Cardiac Fibrosis and Remodeling
  • Peptidase Inhibition and Analysis
  • Blood groups and transfusion
  • Cardiovascular Effects of Exercise
  • GDF15 and Related Biomarkers
  • Systemic Sclerosis and Related Diseases
  • Parvovirus B19 Infection Studies
  • Congenital heart defects research
  • Cardiac Structural Anomalies and Repair
  • Cardiac electrophysiology and arrhythmias
  • ECG Monitoring and Analysis
  • Atrial Fibrillation Management and Outcomes
  • Viral Infections and Immunology Research
  • Prenatal Screening and Diagnostics
  • Eosinophilic Disorders and Syndromes

Phoenix Children's Hospital
2024

Case Western Reserve University
2021-2023

Rainbow Babies & Children's Hospital
2021-2023

University School
2021

University of Colorado Anschutz Medical Campus
2021

Children's Hospital Colorado
2021

University of Colorado Denver
2021

Washington University in St. Louis
2018-2020

St. Louis Children's Hospital
2018

Background Arrhythmias in children are often paroxysmal, complicating the ability to capture abnormal rhythm on routine ECG during an outpatient visit. The Alivecor Kardia Mobile (KM) device is a wireless mobile health (mHealth) that generates single lead tracing with FDA-approved algorithm for detection of atrial fibrillation adults. Objective goal this study assess accuracy interval measurements KM tracings by directly comparing standard 12-lead ECGs pediatric patients. Methods This...

10.1371/journal.pone.0204403 article EN cc-by PLoS ONE 2018-09-27

Objective To describe international surveillance and treatment strategies for managing anti-SSA/Ro autoantibody positive pregnancies.

10.1080/14767058.2024.2323623 article EN cc-by The Journal of Maternal-Fetal & Neonatal Medicine 2024-01-02

. Background: Third-degree atrioventricular block (AVB) is the most common manifestation of Anti-Ro antibody associated fetal cardiac disease. Extranodal findings isolated echogenicity, valvulitis with insufficiency and AV interval prolongation have been reported but not described in large prospective series. Aims: To report occurrence outcomes extranodal subjects followed prospectively since 2020 STOP BLOQ (Surveillance Treatment to Prevent Fetal Likely Occur Quickly) Registry for Neonatal...

10.1161/circ.150.suppl_1.4136984 article EN Circulation 2024-11-11

Introduction:: The management of anti-Ro/SSA positive pregnancies is challenging because fetal atrioventricular (AV) block rare and echo seldom detects reversible injury. Hypothesis: We hypothesized that ambulatory heart rate/rhythm monitoring improves detection AV when compared with echo. Methods: Anti-Ro antibody subjects from 21 US centers at less than 20 weeks gestation were risk stratified into high low anti-Ro60 52 titers the New York University (NYU) core laboratory. Low titer was...

10.1161/circ.148.suppl_1.15936 article EN Circulation 2023-11-07

Introduction: Pediatric and adult dilated cardiomyopathy (DCM) represent distinct entities with divergent gene expression, histopathology, response to medical therapies. Prognostically important serum biomarkers identified in adults have failed provide similar diagnostic prognostic information for children DCM. We hypothesized that pediatric DCM populations display different biomarker profiles. Methods: control (≤18y), DCM, plasma samples were analyzed using the SOMAscan platform...

10.1161/circ.142.suppl_3.13179 article EN Circulation 2020-11-17

10.1007/s40746-021-00230-x article EN Current Treatment Options in Pediatrics 2021-09-29
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