Rukmini Komarlu

ORCID: 0000-0003-4516-3770
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About
Contact & Profiles
Research Areas
  • Congenital Heart Disease Studies
  • Coronary Artery Anomalies
  • Cardiovascular Issues in Pregnancy
  • Cardiac Structural Anomalies and Repair
  • Cardiac Valve Diseases and Treatments
  • Aortic Disease and Treatment Approaches
  • Vascular anomalies and interventions
  • Cardiovascular Function and Risk Factors
  • Tracheal and airway disorders
  • Cardiac Arrhythmias and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Congenital Diaphragmatic Hernia Studies
  • Mechanical Circulatory Support Devices
  • Cardiovascular and Diving-Related Complications
  • Cardiac Imaging and Diagnostics
  • Congenital heart defects research
  • Cardiac tumors and thrombi
  • Ultrasound in Clinical Applications
  • Neonatal and fetal brain pathology
  • Connective tissue disorders research
  • Cardiovascular Effects of Exercise
  • Congenital Anomalies and Fetal Surgery
  • Neonatal Respiratory Health Research
  • Advanced MRI Techniques and Applications
  • Pulmonary Hypertension Research and Treatments

Cleveland Clinic
2014-2025

Cleveland Clinic Lerner College of Medicine
2020-2024

MetroHealth
2022

MetroHealth Medical Center
2022

University of Missouri–Kansas City
2021

Children's Mercy Hospital
2021

Case Western Reserve University
2020

Akron Children's Hospital
2020

Harvard University
2014-2016

Boston Children's Hospital
2011-2015

Ebstein anomaly and tricuspid valve dysplasia are rare congenital malformations associated with high perinatal mortality. The literature consists of small, single-center case series spanning several decades. We performed a multicenter study to assess the outcomes factors mortality after fetal diagnosis in current era.Fetuses diagnosed from 2005 2011 were included 23 centers. primary outcome was mortality, defined as demise or death before neonatal discharge. Of 243 fetuses at mean...

10.1161/circulationaha.115.015839 article EN Circulation 2015-06-10

Objectives. Abnormal diaphragmatic motion secondary to phrenic nerve injury is not uncommon after pediatric cardiothoracic surgery. Fluoroscopy the most frequent method of diagnosis but it carries risks associated with transportation critically ill children and exposure ionizing radiation. Ultrasonography, a reliable diagnostic in adults, eliminates both concerns. Since cardiac intensivists are trained echocardiography, we tested hypothesis that chest ultrasound performed by intensivist...

10.1111/j.1747-0803.2010.00431.x article EN Congenital Heart Disease 2010-11-01

We sought to identify cardiovascular magnetic resonance (CMR) parameters associated with successful univentricular biventricular conversion in patients small left hearts. Patients heart structures and a circulation who underwent CMR prior were retrospectively identified divided into 2 anatomic groups: 1) borderline hypoplastic (BHLHS), 2) right-dominant atrioventricular canal (RDAVC). The primary outcome variable was transplant-free survival circulation. In the BHLHS group (n = 22), 16 (73%)...

10.1186/s12968-014-0073-1 article EN cc-by Journal of Cardiovascular Magnetic Resonance 2014-10-06

We present a unique case of progressive neoaortic root and neoascending aortic dilatation, with poly-valvar regurgitation in patient Marfan syndrome hypoplastic left heart palliated to Fontan procedure. This dilation valvar dysfunction necessitated modified Bentall procedure tricuspid valve repair. Our highlights the impact both primary secondary aortopathy complicating need for mechanical replacement.

10.1177/21501351241313314 article EN World Journal for Pediatric and Congenital Heart Surgery 2025-02-06

Transcatheter pulmonary valve replacement (TPVR) is a mainstay of therapy for right ventricular outflow tract dysfunction, especially in adult congenital heart disease. This study aimed to assess the prevalence, characteristics, and clinical implications hypoattenuating leaflet thickening (HALT) hypoattenuation affecting motion (HAM) after TPVR. was retrospective cohort TPVR performed from 2018 2024. Computed tomography angiography (CTA) assessed HALT/HAM echocardiography gradients. Random...

10.1016/j.jacadv.2025.101599 article EN cc-by-nc-nd JACC Advances 2025-02-15

Background In a recent multicenter study of perinatal outcome in fetuses with Ebstein anomaly or tricuspid valve dysplasia, we found that one third live-born patients died before hospital discharge. We sought to further describe postnatal management strategies and define risk factors for neonatal mortality circulatory at Methods Results This 23-center, retrospective from 2005 2011 included 243 dysplasia. Among patients, clinical echocardiographic were evaluated association palliated versus...

10.1161/jaha.120.016684 article EN cc-by-nc-nd Journal of the American Heart Association 2020-10-20

Purpose To develop and validate a respiratory motion compensation method for free‐breathing cardiac cine imaging. Methods A navigator‐gated steady‐state free precession acquisition (C ine‐Nav ) was developed which preserves the equilibrium state of net magnetization vector, maintains high spatial temporal resolutions standard breath‐hold (BH) acquisition, images entire cycle. Cine image data is accepted only from cycles occurring entirely during end‐expiration. Prospective validation...

10.1002/mrm.25275 article EN Magnetic Resonance in Medicine 2014-04-28

Objective The objective of this study was to identify patient and hospitalization characteristics associated with in-hospital mortality in infants truncus arteriosus. Methods We conducted a retrospective analysis large administrative database, the National Inpatient Sample data set Healthcare Cost Utilization Project for years 2002 2017. also sought evaluate resource utilization subgroup subjects arteriosus 22q11.2 deletion syndrome. Neonates were identified by ICD-9 ICD-10 codes. Hospital...

10.1111/jocs.14730 article EN Journal of Cardiac Surgery 2020-06-19

This report describes a fetus presenting with intrauterine tachycardia and hydrops fetalis. Soon after birth the neonate was noted to be in torsades de pointes that responded dramatically medical management. Long QT syndrome (LQTS) diagnosed on electrocardiogram obtained soon birth. The prognosis is poor when LQTS presents utero or during first week of life. However, our infant did well management has remained free arrhythmias at follow-up.

10.1111/j.1540-8159.2011.03040.x article EN Pacing and Clinical Electrophysiology 2011-03-14

10.1016/j.jpeds.2021.12.025 article EN The Journal of Pediatrics 2021-12-22

Cor Triatriatum Dexter ( CTD ) is a rare congenital anomaly involving the systemic venous valves. Failure of regression right‐sided sinus venosus valve leads to abnormal septation right atrium and variety atrial tricuspid obstructive lesions. The presentation can be varied ranging from asymptomatic persistent neonatal cyanosis. We describe late diagnosis in 10‐month‐old male with hypoxia despite balloon valvuloplasty for mild pulmonic stenosis large secundum septal defect mildly hypoplastic...

10.1111/echo.14175 article EN Echocardiography 2018-11-09

Dextro-transposition of the great arteries (D-TGA) is second-most common cyanotic congenital heart disease with variable coronary artery anatomy. The arterial switch procedure has revolutionized outcomes for this defect, anatomy being a key determinant both short- and long-term following surgical repair. assessment usually undertaken in postnatal period by transthoracic echocardiography, prenatally not well studied. We sought to assess feasibility delineating on fetal echocardiograms small...

10.4103/jcecho.jcecho_34_21 article EN Journal of Cardiovascular Echography 2021-01-01

The authors of this paper have no declarations. No grants or financial support has been received. There are conflicts interest. This is not currently under consideration elsewhere.

10.1111/jocs.13737 article EN Journal of Cardiac Surgery 2018-06-13

Abstract Aortic dissection causes significant morbidity and mortality in adults treatment guidelines are based on well-documented risk factors. Conversely, after orthotopic heart transplantation is very rare, especially the absence of infection, hypertension, or donor–recipient aortic size mismatch. Several forms CHD associated with dilatation, but incidence aneurysm children also low, which makes use adult challenging. We present a 17-year-old Amish female homozygous gene mutation MYBPC3...

10.1017/s1047951119001811 article EN Cardiology in the Young 2019-08-27

10.1016/j.jocmr.2024.100414 article EN cc-by-nc-nd Journal of Cardiovascular Magnetic Resonance 2024-01-01

. Background: Third-degree atrioventricular block (AVB) is the most common manifestation of Anti-Ro antibody associated fetal cardiac disease. Extranodal findings isolated echogenicity, valvulitis with insufficiency and AV interval prolongation have been reported but not described in large prospective series. Aims: To report occurrence outcomes extranodal subjects followed prospectively since 2020 STOP BLOQ (Surveillance Treatment to Prevent Fetal Likely Occur Quickly) Registry for Neonatal...

10.1161/circ.150.suppl_1.4136984 article EN Circulation 2024-11-11
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