A5066909081- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Cardiac Arrhythmias and Treatments
- Intensive Care Unit Cognitive Disorders
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
- Respiratory Support and Mechanisms
- Mechanical Circulatory Support Devices
- Cardiovascular Effects of Exercise
- Coronary Artery Anomalies
- Genetic Neurodegenerative Diseases
- Viral Infections and Immunology Research
- Neuroendocrine Tumor Research Advances
- Pneumonia and Respiratory Infections
- Emergency and Acute Care Studies
- Pregnancy-related medical research
- Infective Endocarditis Diagnosis and Management
- Blood Pressure and Hypertension Studies
- Cardiomyopathy and Myosin Studies
- SARS-CoV-2 detection and testing
- Cardiac pacing and defibrillation studies
- Systemic Sclerosis and Related Diseases
- Heparin-Induced Thrombocytopenia and Thrombosis
Cleveland Clinic
2023-2025
University Hospitals Birmingham NHS Foundation Trust
2022
University of North Carolina at Chapel Hill
2018-2021
Public Health Scotland
2021
National Health and Medical Research Council
2021
Intensive Care National Audit & Research Centre
2021
Transcatheter pulmonary valve replacement (TPVR) is a mainstay of therapy for right ventricular outflow tract dysfunction, especially in adult congenital heart disease. This study aimed to assess the prevalence, characteristics, and clinical implications hypoattenuating leaflet thickening (HALT) hypoattenuation affecting motion (HAM) after TPVR. was retrospective cohort TPVR performed from 2018 2024. Computed tomography angiography (CTA) assessed HALT/HAM echocardiography gradients. Random...
Background Pregnant patients with single ventricle (SV) physiology carry a high risk of spontaneous pregnancy loss (SPL), yet the clinical factors contributing to this are not well defined. Methods Single-centre retrospective study pregnant SV seen in cardio-obstetrics clinic over past 20 years chart review their obstetric history. Patients without known outcome were excluded. Univariable Bayesian panel-data random effects logit was used model SPL. Results The included 44 pregnancies, live...
Sudden death is a leading cause of deaths nationally. Definitions sudden vary greatly, resulting in imprecise estimates its frequency and incomplete knowledge risk factors. The degree to which time-based coronary artery disease (CAD) criteria impacts factors unknown. Here, we apply these registry all-cause assess impact on unexpected North Carolina (SUDDEN) project out of-hospital, adjudicated, attended by Emergency Medical Services. Deaths were not excluded time since last seen or alive...
Abstract Introduction Concomitant left bundle branch area pacing (LBBAP) with atrioventricular (AV) nodal ablation is emerging as a viable management option in atrial fibrillation refractory to medical management. Its viability patients pulmonary disease and unknown. Methods results This retrospective, observational cohort study consecutive who underwent concomitant LBBAP AV advanced at the Cleveland Clinic Fairview Hospital between January 2019 2023. Patient characteristics, comorbidities,...
Abstract Obesity has been found to increase the risk of musculoskeletal pain (MSP) in other settings, but our knowledge, influence increased body mass index on outcomes after common trauma exposures such as motor vehicle collision (MVC) not assessed. In addition, obesity results biomechanical changes, well physiologic changes including reduced hypothalamic pituitary adrenal axis negative feedback inhibition, mechanisms by which may result worse post-traumatic remain poorly understood. this...
microRNAs (miRNAs) regulate messenger RNA (mRNA) abundance and translation during key developmental processes including muscle differentiation. Assessment of miRNA targets can provide insight into biology gene expression profiles altered by disease. mRNA libraries were generated from C2C12 myoblasts differentiation, predicted identified based on presence binding sites reciprocal expression. Seventeen miRNAs differentially expressed at all time intervals (comparing days 0, 2, 5) enriched for...
Introduction: Immune-mediated inflammatory disease (IMID) is a subset of autoimmune diseases including systemic lupus erythematosus, rheumatoid arthritis, and psoriasis that emerging as risk factor for many cardiovascular valvular disease. Objectives: To determine whether IMID associated with frequent early development bioprosthetic valve failure (BVF) after surgical aortic replacement (SAVR) transcatheter (TAVR). Methods: Serial echocardiograms patients who underwent SAVR TAVR at Cleveland...
Abstract Chronic pain is a significant comorbidity of burn injury affecting up to 60% survivors. Currently, no treatments are available prevent chronic after injury. Accumulating evidence suggests that omega-3 fatty acids (O3FAs) improve symptoms across range painful conditions. In this study, we evaluated whether low peritraumatic levels O3FA predict greater severity during the year Burn survivors undergoing skin autograft were recruited from three participating centers. Plasma (n = 77)...