Alexandra B. Yonts

ORCID: 0000-0001-7290-3258
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About
Contact & Profiles
Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Respiratory viral infections research
  • Influenza Virus Research Studies
  • Viral Infections and Immunology Research
  • Pneumonia and Respiratory Infections
  • Vaccine Coverage and Hesitancy
  • Kawasaki Disease and Coronary Complications
  • Animal Virus Infections Studies
  • Bacterial Infections and Vaccines
  • Antibiotic Use and Resistance
  • Streptococcal Infections and Treatments
  • Orthopedic Infections and Treatments
  • Child and Adolescent Health
  • Neonatal Respiratory Health Research
  • Cytomegalovirus and herpesvirus research
  • Mosquito-borne diseases and control
  • Antibiotics Pharmacokinetics and Efficacy
  • Blood disorders and treatments
  • Pharmaceutical studies and practices
  • Neutropenia and Cancer Infections
  • Infectious Encephalopathies and Encephalitis
  • Bacterial Identification and Susceptibility Testing
  • Complement system in diseases
  • Hematological disorders and diagnostics
  • Emergency and Acute Care Studies

Children's National
2018-2025

George Washington University Hospital
2022-2025

George Washington University
2019-2024

National Hospital
2024

University of California Davis Medical Center
2015

The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts that provides advice to the Centers for Disease Control Prevention, normally meets 3 times per year develop US vaccine recommendations. ACIP met June 21-23, 2023, discuss respiratory syncytial virus (RSV) vaccines, influenza pneumococcal meningococcal COVID-19 vaccines. also held special meeting August 3, RSV prophylaxis in infants. This update summarizes proceedings these meetings are most...

10.1542/peds.2023-063955 article EN PEDIATRICS 2023-08-29

The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts that provides advice to the Centers for Disease Control Prevention, normally meets 3 times per year develop US vaccine recommendations. ACIP met October 23-24, 2024, discuss influenza vaccines, chikungunya coronavirus disease (COVID-19) RSV immunizations, meningococcal human papillomavirus (HPV) pneumococcal adult child/adolescent immunization schedule revisions. This update summarizes...

10.1542/peds.2024-069926 article EN other-oa PEDIATRICS 2025-01-24

The incidence of bacteremia at the onset pediatric febrile neutropenia (FN) 2 academically linked institutions was 9.84%, and subsequent blood cultures performed for children with persistent FN yielded an 4.21%. Until risk factors new-onset in patients being treated can be identified diagnostic methods improved, compliance national guidelines is recommended.

10.1093/jpids/piu145 article EN Journal of the Pediatric Infectious Diseases Society 2015-02-04

The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts that provides advice to the Centers for Disease Control Prevention, normally meets 3 times per year develop US vaccine recommendations. ACIP met October 25 26, 2023, discuss meningococcal vaccines, mpox respiratory syncytial virus (RSV) influenza coronavirus disease 2019 (COVID-19) combined pediatric adult immunization schedules 2024. also held special meetings September 12 22 COVID-19...

10.1542/peds.2023-064990 article EN other-oa PEDIATRICS 2023-12-14

The Advisory Committee on Immunization Practices, a group of medical and public health experts that provides advice to the Centers for Disease Control Prevention, normally meets 3 times per year develop US vaccine recommendations. Practices met February 28 29, 2024, discuss coronavirus disease 2019 vaccines, chikungunya diphtheria-tetanus vaccine, influenza polio respiratory syncytial virus meningococcal pneumococcal Vaxelis (Diphtheria, Tetanus, Pertussis, Inactivated Poliovirus,...

10.1542/peds.2024-066653 article EN PEDIATRICS 2024-03-29

Abstract Background PECOS is an ongoing study aimed to characterize long-term outcomes following pediatric SARS-CoV-2 infection. Methods This a cross-sectional analysis of infected and uninfected cohorts at baseline. Participants (0–21 years) with laboratory-confirmed infection were enrolled as infected. Uninfected defined individuals without history or laboratory evidence Outcome measures included demographics, medical history, review symptoms, physical exam, cardiopulmonary evaluation...

10.1038/s41390-024-03777-1 article EN cc-by Pediatric Research 2024-12-18

Background: The sequelae of COVID-19 vaccine associated myocarditis (C-VAM) are incompletely understood. We sought to characterize the clinical course, myocardial injury, and outcomes in C-VAM.Methods: In this retrospective observational cohort multicenter study across 38 hospitals U.S., we compared cardiac imaging characteristics 333 C-VAM patients from April 2021 November 2022 with those 100 multisystem inflammatory syndrome children (MIS-C) explored risk factors for injury C-VAM.Findings:...

10.2139/ssrn.4681858 preprint EN 2024-01-01

The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts that provides advice to the Centers for Disease Control Prevention, normally meets 3 times per year develop US vaccine recommendations. ACIP met June 26 through 28, 2024. This update summarizes proceedings this meeting, with an emphasis topics are most relevant pediatric population. Major updates clinicians include COVID-19 influenza recommendations 2024 2025 season, meningococcal...

10.1542/peds.2024-068310 article EN PEDIATRICS 2024-07-30

10.1016/j.jpeds.2021.12.025 article EN The Journal of Pediatrics 2021-12-22

The inpatient setting is often underutilized as a venue for providing pediatric vaccines. During the 2019 novel coronavirus (COVID-19) pandemic, our hospital began vaccination program to provide access COVID-19 vaccines eligible inpatients. Our objective was describe establishment and assess impact of inpatients.All admitted patients were screened eligibility interest in upon admission from April 27, 2021 until February 12, 2022. For those vaccination, their recorded shared with clinical...

10.1542/hpeds.2022-006804 article EN Hospital Pediatrics 2023-10-09

The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts that provides expert advice to the Centers for Disease Control Prevention, normally meets three times per year develop US vaccine recommendations. ACIP increased its meeting frequency over past 2.5 years address vaccine-related issues during severe acute respiratory syndrome coronavirus 2 pandemic. They met discuss updating disease-2019 (COVID-19) booster dose recommendations September 1,...

10.1093/jpids/piac114 article EN Journal of the Pediatric Infectious Diseases Society 2022-10-28

Background: Clinical practice guidelines recommend using narrow-spectrum antibiotics to treat uncomplicated pneumonia in children. This quality improvement (QI) project aimed evaluate if QI methods could improve guideline-concordant antibiotic prescribing at hospital discharge for children with pneumonia. Methods: For this single-center project, we implemented interventions serial plan-do-study-act cycles, focusing on the key drivers targeting general pediatric inpatient resident teams....

10.1097/pq9.0000000000000711 article EN cc-by-nc-nd Pediatric Quality and Safety 2023-11-01

The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts who provides expert advice to the Centers for Disease Control Prevention, normally meets three times per year develop U.S. vaccine recommendations. ACIP met February 22-24, 2023, discuss mpox vaccine, influenza vaccines, pneumococcus meningococci polio respiratory syncytial virus (RSV) chikungunya dengue COVID-19 vaccines.

10.1093/jpids/piad026 article EN Journal of the Pediatric Infectious Diseases Society 2023-04-24

Hemolytic uremic syndrome (HUS) describes a clinical presentation of acute kidney injury, microangiopathic hemolytic anemia and thrombocytopenia. Five to 15% HUS cases are related Streptococcus pneumoniae infection, most often meningitis or pneumonia. Despite the introduction PCV13 decrease in invasive pneumococcal disease children, incidence pneumococcal-related (pHUS) is rising for unclear reasons. Efforts determine whether certain serotypes increase risk pHUS hampered by negative cultures...

10.1093/ofid/ofy210.1948 article EN cc-by-nc-nd Open Forum Infectious Diseases 2018-11-01

Abstract Background Community-acquired pneumonia (CAP) is the most common diagnosis in hospitalized children. The Pediatric Infectious Diseases Society and of America published evidenced-based clinical practice guidelines for management CAP children 3 months age or older 2011. These are not consistently followed. Our objective was to evaluate if quality improvement (QI) methods could improve guideline-concordant antibiotic prescribing, specifically addressing use oral third-generation...

10.1093/ofid/ofz360.1003 article EN cc-by-nc-nd Open Forum Infectious Diseases 2019-10-01

Abstract Background Acute Flaccid Myelitis (AFM), diagnosed almost exclusively in children, is characterized by sudden onset flaccid weakness one or more extremities with distinct gray matter spinal cord lesions on magnetic resonance imaging (MRI), without cerebrospinal fluid (CSF) pleocytosis. Outbreaks of AFM have occurred biennially since 2014. Although the definitive causative agent(s) remain unknown, current data support an association Enteroviruses D68 and A71. Treatment supportive...

10.1093/ofid/ofaa439.480 article EN cc-by-nc-nd Open Forum Infectious Diseases 2020-10-01

Abstract Background Acute hematogenous osteomyelitis (AHO) affects about 2-13 children per 100,000 in developed countries each year. Staphylococcus aureus is the most common causative pathogen of AHO and, due to antibiotic resistant strains this species, a microbial diagnosis often desired. Blood and bone cultures may identify pathogens determine susceptibilities but obtaining carries risks. The benefit patients having identified disputed further research required address question....

10.1093/ofid/ofac492.1142 article EN cc-by Open Forum Infectious Diseases 2022-12-01
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