A5068067865- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Mechanical Circulatory Support Devices
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Kawasaki Disease and Coronary Complications
- Cardiovascular Effects of Exercise
- Photosynthetic Processes and Mechanisms
- Cardiac Valve Diseases and Treatments
- Chronic Disease Management Strategies
- Ultrasound in Clinical Applications
- Neurological disorders and treatments
- ATP Synthase and ATPases Research
- Cardiac Arrest and Resuscitation
- Down syndrome and intellectual disability research
- Pericarditis and Cardiac Tamponade
- SARS-CoV-2 and COVID-19 Research
- Congenital Diaphragmatic Hernia Studies
- Heat shock proteins research
- Congenital heart defects research
- COVID-19 Clinical Research Studies
Children's Mercy Hospital
2016-2025
University of Missouri–Kansas City
2019-2025
College of the Holy Cross
2023
University of Kansas Medical Center
2018
National Cancer Institute
2018
University of Kansas
2018
Mercy Hospital
2015-2017
Erasmus MC
2016
Duke Medical Center
2011-2015
Duke University
2014-2015
Infants with persistent pulmonary hypertension of the newborn (PPHN) have elevated vascular resistance that can lead to right ventricular (RV) failure and death. Clinicians must decide which infants will fail conventional therapy require transfer extra corporeal membrane oxygenation (ECMO) centres, but accurate echocardiographic predictors not been identified. We assessed measurements RV pressure function in predicting progression death or ECMO PPHN. Echocardiograms for ≥35-week gestation a...
In adolescents and adults with tetralogy of Fallot (TOF), right ventricle (RV) electromechanical dyssynchrony (EMD) due to bundle branch block (RBBB) is associated reduced exercise capacity RV dysfunction. While the development RBBB following surgical repair (rTOF) a frequent sequela, it not known whether EMD present in every patient immediately rTOF. The specific timing onset rTOF therefore provides an opportunity assess acute simultaneous acquisition EMD. Transthoracic echocardiography...
Background Children with repaired conotruncal abnormalities (CTA) are at risk of progressive aortic dilation and deteriorating elasticity even after surgical correction. Strain imaging, using a 2-dimensional speckle tracking echocardiography (2D-STE), has been used for arterial stiffness assessment, but pediatric data still lacking. We investigated the feasibility, reproducibility, clinical value 2D-STE derived ascending aorta (AAo) in children CTA. Methods 22 patients CTA were included...
Abstract Objectives: Many children diagnosed with COVID-19 infections did not require hospitalisation. Our objective was to analyse electrocardiographic changes in asymptomatic, mild or moderate who hospitalisation Methods: All are seen a paediatric cardiology clinic had that and at least one electrocardiogram after their diagnosis were included this retrospective analysis. Records reviewed determine disease severity presence of Long COVID. Rhythm assessment, atrial enlargement, ventricular...
The biogenesis of multimeric protein complexes the inner mitochondrial membrane in yeast requires a number nuclear-coded ancillary proteins. One these, Pet100p, is required for cytochrome c oxidase. Previous studies have shown that Pet100p not synthesis, processing, or targeting oxidase subunits to mitochondrion nor heme A biosynthesis. Here, we report does affect localization subunit polypeptides but instead functions after they arrived at membrane. We also localized wild type cells, where...
ABSTRACT Adults with Down syndrome are less physically active than their typically developed peers. The purpose of this study was to assess the feasibility delivering moderate-to-vigorous exercise sessions, led by a trained health educator using real-time video conferencing, groups young adults in homes. Participants were randomized 30-min group sessions either one or two times week delivered on an iPad mini tablet computer Zoom conferencing application, and asked attend individual...
Nearly all individuals with Down Syndrome (DS) display pathology associated Alzheimer's disease (AD) beginning as early age 30. Previous research in typically developed adults suggests that increased moderate-to-vigorous physical activity (MVPA) may improve cognitive function and protect against age-related structural functional changes the brain; however, potential impact of MVPA on development AD DS has not been evaluated. Despite positive cognition risk, participation among young is low....
Objective The aim of the study was to determine right and left ventricle deformation parameters in patients with transposition great arteries who had undergone atrial or arterial switch procedures. Setting Patients are born a systemic ventricle. Historically, operation, which remains ventricle, performed. These have increased rates morbidity mortality. We used cardiac MRI Velocity Vector Imaging analysis characterize compare ventricular myocardial an operation. Design history these...
Obesity is associated with diminished myocardial function as measured by strain echocardiography in children and young adults normal cardiac anatomy. Data are lacking about the effect of obesity on patients a single ventricle. In this study, relationship between body mass index (BMI) ventricle Fontan population was assessed.