E. Profita

ORCID: 0000-0003-1578-3346
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About
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Research Areas
  • Transplantation: Methods and Outcomes
  • Mechanical Circulatory Support Devices
  • Renal Transplantation Outcomes and Treatments
  • Cardiac Structural Anomalies and Repair
  • Heart Failure Treatment and Management
  • Congenital Heart Disease Studies
  • Organ Transplantation Techniques and Outcomes
  • Hepatitis C virus research
  • Pneumonia and Respiratory Infections
  • HIV/AIDS drug development and treatment
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Polyomavirus and related diseases
  • Cancer Treatment and Pharmacology
  • Innovations in Medical Education
  • Cytomegalovirus and herpesvirus research
  • Viral Infections and Immunology Research
  • Cardiovascular Function and Risk Factors
  • Global Health and Surgery
  • Antibiotics Pharmacokinetics and Efficacy
  • Animal Virus Infections Studies
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Child and Adolescent Health
  • SARS-CoV-2 and COVID-19 Research
  • Diabetes Treatment and Management
  • Adenosine and Purinergic Signaling

Stanford University
2019-2024

Palo Alto University
2020-2024

Lucile Packard Children's Hospital
2019-2022

Stanford Medicine
2021

Boston Children's Hospital
2018-2019

Background Previous studies suggest that infant heart transplant (HT) recipients are at higher risk of developing severe primary graft dysfunction (PGD) than older children. We sought to identify factors for PGD in HT recipients. Methods and Results identified all aged <1 year the United States during 1996 2015 using Organ Procurement Transplant Network database. linked their data ELSO (Extracorporeal Life Support Organization) registry those with PGD, defined by initiation extracorporeal...

10.1161/jaha.121.021082 article EN cc-by-nc-nd Journal of the American Heart Association 2021-06-29

10.1016/j.jpeds.2021.12.025 article EN The Journal of Pediatrics 2021-12-22

Abstract Primary graft dysfunction following HTx is associated with significant morbidity and mortality. This study aimed to assess the incidence of, risk factors for, outcomes of children requiring ECMO within 24 hours HTx. utilized a linked PHIS/SRTR database pediatric recipients (2002‐2016). Post‐HTx was identified using inpatient billing data. Logistic regression assessed for post‐HTx ECMO. Kaplan‐Meier analyses in‐hospital mortality post‐discharge survival. A total 2820 patients were...

10.1111/petr.13414 article EN Pediatric Transplantation 2019-04-11

Access to pediatric sub-specialty training is a critical unmet need in many resource-limited settings. In Rwanda, only two cardiologists are responsible for the country's clinical care of population 12 million, along with medical education all trainees. To strengthen physician opportunities, we developed an e-learning curriculum cardiology. This aimed "flip classroom", allowing residents learn key cardiology concepts digitally before in-person session specialist, thus efficiently utilizing...

10.1186/s12909-022-03222-z article EN cc-by BMC Medical Education 2022-03-16

Abstract Background Pediatric heart transplantation (HT) continues to be limited by the shortage of donor organs, distance constraints, and number potential offers that are declined due presence multiple risk factors. Methods We report a case successful pediatric HT in which factors were mitigated through combination innovative utilization improvement strategies. Results An 11‐year‐old, 25‐kilogram child with cardiomyopathy pulmonary hypertension, on chronic milrinone therapy anticoagulated...

10.1111/petr.14584 article EN Pediatric Transplantation 2023-07-20

Abstract Background Early detection of cardiac allograft rejection is crucial for post‐transplant graft survival. Despite the progress made in immunosuppression strategies, acute cellular remains a serious complication during and after first year, there continued lack consensus regarding its treatment, especially pediatric transplant patients. Methods An open request was placed via listserv to membership Pediatric Heart Transplant Society (PHTS). Along with broad literature search, numerous...

10.1111/petr.14393 article EN Pediatric Transplantation 2022-11-14

10.1016/j.healun.2024.02.304 article EN The Journal of Heart and Lung Transplantation 2024-04-01

10.1016/j.healun.2024.02.969 article EN The Journal of Heart and Lung Transplantation 2024-04-01

Although adult transplant centers are successfully transplanting organs from hepatitis C virus (HCV)-infected donors with detectable viral load by nucleic acid testing (NAT+) into HCV-negative recipients, this practice has not yet been adopted widely the pediatric heart community.

10.1111/petr.14879 article EN Pediatric Transplantation 2024-10-27
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