Olivia Frosch
A5074124516- Viral Infections and Immunology Research
- SARS-CoV-2 and COVID-19 Research
- Kawasaki Disease and Coronary Complications
- Animal Virus Infections Studies
- Cerebrovascular and Carotid Artery Diseases
- Adipose Tissue and Metabolism
- Heparin-Induced Thrombocytopenia and Thrombosis
- Childhood Cancer Survivors' Quality of Life
- Obsessive-Compulsive Spectrum Disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Metabolism and Genetic Disorders
- Alcoholism and Thiamine Deficiency
- Cardiac Structural Anomalies and Repair
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Healthcare Systems and Technology
- Cardiovascular Health and Disease Prevention
- Regulation of Appetite and Obesity
- Pericarditis and Cardiac Tamponade
- Child and Adolescent Health
- Nutritional Studies and Diet
- Folate and B Vitamins Research
University of Michigan
2021-2024
C. S. Mott Children's Hospital
2021-2024
Michigan Medicine
2021
Children's Hospital of Philadelphia
2021
New York University
2014-2017
Nathan Kline Institute for Psychiatric Research
2017
Boston Children's Hospital
2016
Washington University in St. Louis
2012
Background: Understanding the clinical course and short-term outcomes of suspected myocarditis after coronavirus disease 2019 (COVID-19) vaccination has important public health implications in decision to vaccinate youth. Methods: We retrospectively collected data on patients <21 years old presenting before July 4, 2021, with within 30 days COVID-19 vaccination. Lake Louise criteria were used for cardiac MRI findings. Myocarditis cases classified as confirmed or probable basis Centers...
Cerebral perfusion was evaluated in 87 subjects prospectively enrolled three study groups—healthy controls (HC), patients with insulin resistance (IR) but not diabetes, and type 2 diabetes mellitus (T2DM). Participants received a comprehensive 8-hour clinical evaluation arterial spin labeling magnetic resonance imaging (MRI). In order of decreasing significance, an association found between cerebral blood flow (CBF) sex, waist circumference, diastolic pressure (BP), end tidal CO , verbal...
Importance Data are limited regarding adverse reactions after COVID-19 vaccination in patients with a history of multisystem inflammatory syndrome children (MIS-C). The lack vaccine safety data this unique population may cause hesitancy and concern for many families health care professionals. Objective To describe following MIS-C. Design, Setting, Participants In multicenter cross-sectional study including 22 North American centers participating National Heart, Lung, Blood Institute,...
To evaluate differences in cerebrovascular reactivity (CVR) to mild hypercapnia obese/overweight individuals with and without insulin resistance (IR) compared comparable lean controls.A total of 60 cognitively normal participants (20 controls 24 16 IR) were evaluated using a high spatial resolution arterial spin labeling MRI technique at rest during hypercapnia. We analyzed group CVR cerebral cortex ascertained the relationships between CVR, IR, body mass index (BMI).Obese/overweight IR had...
Background: The sequelae of COVID-19 vaccine associated myocarditis (C-VAM) are incompletely understood. We sought to characterize the clinical course, myocardial injury, and outcomes in C-VAM.Methods: In this retrospective observational cohort multicenter study across 38 hospitals U.S., we compared cardiac imaging characteristics 333 C-VAM patients from April 2021 November 2022 with those 100 multisystem inflammatory syndrome children (MIS-C) explored risk factors for injury C-VAM.Findings:...
Inpatient rounding serves numerous roles. The American Academy of Pediatrics recommends a family-centered bedside model. Residents identified physical examination teaching during and satisfaction with rounds as areas for improvement. A resident group developed project utilizing quality improvement (QI) methodology to address these concerns. We aimed increase the frequency most or every day on single inpatient unit by 20% over 1 year, secondary goals percentage interns spending one hour more...
A previously healthy 16-year-old female patient experi- enced chest pain 2 days after the second dose of Pfizer-BioNTech COVID-19 vaccine.Workup revealed elevated high-sensitivity cardiac troponin T level and electrocardiographic abnormalities, prompting hospitalization with diagnosis myocarditis.Peak was 3492 pg/mL (reference range, 0-19 pg/mL); three echocardiograms were normal.Nonsteroidal anti-inflammatory drug therapy resulted in symptomatic improvement.Cardiac MRI performed 6 weeks...