A5059717299- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Immunology Research
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Kawasaki Disease and Coronary Complications
- Vascular anomalies and interventions
- Coronary Artery Anomalies
- Cardiac pacing and defibrillation studies
- Cardiac Valve Diseases and Treatments
- Surgical Simulation and Training
- Shoulder and Clavicle Injuries
- Cardiac Imaging and Diagnostics
- Advanced Memory and Neural Computing
- Cardiovascular Syncope and Autonomic Disorders
- RNA regulation and disease
- CCD and CMOS Imaging Sensors
- Heart Failure Treatment and Management
- Animal Virus Infections Studies
- Trauma Management and Diagnosis
- Cardiac electrophysiology and arrhythmias
- Cardiac and Coronary Surgery Techniques
- Anatomy and Medical Technology
- Cardiovascular Conditions and Treatments
University of Illinois Chicago
2022-2024
Illinois College
2024
University of Mississippi Medical Center
2019-2024
Jackson Memorial Hospital
2019-2024
Carle Foundation Hospital
2022
Lehigh Valley Hospital-Pocono
2022
Peoria campus of the University of Illinois System
2021
University of Florida
2010-2021
University of Mississippi
2019-2020
DELL (United States)
2018
In this study, we aimed to characterize the clinical presentation, short-term prognosis, and myocardial tissue changes as noted on cardiovascular magnetic resonance (CMR) or cardiac MRI in pediatric patients with coronavirus disease 2019 vaccination-associated myocarditis (C-VAM).In retrospective multicenter study across 16 US hospitals, <21 years of age a diagnosis C-VAM were included compared cohort multisystem inflammatory syndrome children. Younger children older adolescents.Sixty-three...
Background and AimsFor patients with congenitally corrected transposition of the great arteries (ccTGA), factors associated progression to end-stage congestive heart failure (CHF) remain largely unclear.
Background:Cardiac Resynchronization Therapy(CRT) is a key treatment for heart failure(HF) in acquired disease, but its benefits adults with congenital disease and systemic right ventricle(sRV) remain unclear. This study aimed to assess whether CRT improves outcomes patients sRV. Methods:This analysis was part of an international, retrospective data from 33 centers including patients>18years transposition the great arteries(TGA) following atrial switch operation congenitally corrected...
The spectrum of congenital heart disease is extremely varied, from simple septal defects all the way up to complex heterotaxy with multiple overlapping congenitally malformed regions heart. While surgical repair has come a long since first cardiac surgery, B-T-T shunt, an unmet need remains as population continues experience sudden arrest at greater rate than general population. Many advances in pacing and cardioversion have occurred address bradyarrhythmias tachyarrhythmias, but these carry...
The recent explosion in the popularity of Deep Learning (DL) is due to a combination improved algorithms, access large datasets and increased computational power. This had led plethora open-source DL frameworks, each with varying characteristics capabilities. End users are then left difficult task determining software hardware configurations get optimal performance from framework. We share our experiences develop best practices for training TensorFlow, MXNet Caffe2. paper also looks at...
MicroRNA (miRNA)-mediated gene regulation has become a major focus in many biological processes. GW182 and its long isoform TNGW1 are marker proteins of GW/P bodies bind to Argonaute the RNA induced silencing complex. The goal this study is further define distinguish repression domain(s) human GW182/TNGW1. Two non-overlapping regions, Δ12 (amino acids 896–1219) containing Ago hook Δ5 1670–1962) RRM, both comparable tethering assay. Mapping data showed that RRM flanking sequences Δ5, but not...
Patients with systemic right ventricle (SRV), either d-transposition of the great arteries following an atrial switch procedure or congenitally corrected transposition arteries, develop severe ventricular dysfunction, prompting appropriate medical therapy. However, efficacy beta-blockers and angiotensin receptor blockers angiotensin-converting enzyme inhibitors (ACEI) in SRV patients is unproven. The objective this study was to determine effects ACEI/ARB on outcomes after accounting for...
Planning corrective and palliative surgery for patients who have complex congenital heart disease often relies on the assessment of cardiac anatomy using two-dimensional noninvasive imaging modalities (echocardiography, magnetic resonance imaging, computed tomography scan). Advances in now include use three-dimensional (3D) reconstruction tools that produce 3D images printouts. There is scant evidence available literature as to what effect availability printouts defects has surgical...
Background: The sequelae of COVID-19 vaccine associated myocarditis (C-VAM) are incompletely understood. We sought to characterize the clinical course, myocardial injury, and outcomes in C-VAM.Methods: In this retrospective observational cohort multicenter study across 38 hospitals U.S., we compared cardiac imaging characteristics 333 C-VAM patients from April 2021 November 2022 with those 100 multisystem inflammatory syndrome children (MIS-C) explored risk factors for injury C-VAM.Findings:...
Junctional ectopic tachycardia (JET) is a potentially life-threatening postoperative arrhythmia in children with specific congenital heart defects and can contribute significantly to morbidity for at-risk populations. In adults, β1-adrenergic receptor (ADRB1) β2-adrenergic (ADRB2) genotypes have been associated increased risk arrhythmias. However, their association unknown. We aimed test associations between ADRB1 ADRB2 JET patients defects. Children who underwent cardiac surgery were...
Penetrating cardiac injuries with extensive intracardiac components and minimal epicardial are a rare presentation. A 31-year-old male presented complex mitral valve ventricular septal partial atrioventricular disruption but hardly visible injuries; the patient's presentation, progression of successful management discussed.
Background/Aim: We previously reported that late gadolinium enhancement (LGE) on cardiac MRI (CMR) was as high 82% in pediatric patients with COVID-19 vaccine-associated myocarditis (C-VAM) despite mild clinical symptoms and normal left ventricular function. As LGE can be a harbinger for future adverse events including arrhythmias, heart failure or sudden death, we sought to identify predictors C-VAM, specifically assessing troponin screening marker C-VAM at risk myocardial scarring who...
Background: Möbius syndrome is a rare congenital condition which presents not merely with 6th and 7th nerve palsies, but involves gaze paresis associated craniofacial, limb, other abnormalities. Heterogeneity well known in patients rather than being of familial inheritance based on cases, it much more recognized as sporadic syndrome. We report an infant features cardiac rhabdomyomas the absence tuberous sclerosis.Materials methods: Observational case seen at tertiary academic center genetic...
The natural history of tetralogy Fallot depends on whether a transannular pulmonary valve patch or shunt surgery was necessary in infancy. This case illustrates the feasibility cardiac rest extracorporeal membranous oxygenation for very ill adult with conduit endocarditis who received right ventricle–to–pulmonary artery valveless later transcatheter replacement. (Level Difficulty: Advanced.)
Congenital diaphragmatic hernias (CDH) can induce life-threatening pulmonary hypertension and right heart failure. The patent ductus arteriosus (PDA) is often maintained in CDH to allow for decompression into the systemic circulation. However, if PDA becomes hemodynamically significant, closure may be indicated. Traditional methods rely on pharmacological closure. In this report, we document a rare transcatheter of significant PDA.
Background: Although several factors have been cited for risk stratification in patients with simple transposition of the great arteries (dTGA), no single predictor emerges consistently. We aimed to assess survival and determine associated a large cohort dTGA adults atrial switch. Methods Results: included 1,169 (median age 28.1 years, 38.7% female) under regular follow-up at 28 institutions between 2002 2019. The primary outcome was composite death, mechanical circulatory support (MCS)...
Background: Occasionally patients with congenitally corrected transposition of the great arteries (ccTGA) exhibit little clinical evidence cardiovascular limitation even to their 8th decade. We aimed assess survival prospects in a large cohort ccTGA adults. Methods & Results: included 555 adults (median age 33.0 years, 48.3% female) under regular follow-up at 28 institutions between 2002 and 2019. The primary outcome was composite death, mechanical circulatory support (MCS) heart...