Songqing Li

ORCID: 0000-0001-6800-9106
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About
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Research Areas
  • Analytical chemistry methods development
  • Electrochemical Analysis and Applications
  • RNA Research and Splicing
  • Pesticide Residue Analysis and Safety
  • Analytical Chemistry and Chromatography
  • RNA Interference and Gene Delivery
  • Ionic liquids properties and applications
  • RNA regulation and disease
  • Electrochemical sensors and biosensors
  • Energetic Materials and Combustion
  • Advanced Surface Polishing Techniques
  • Microstructure and mechanical properties
  • Analytical Chemistry and Sensors
  • Advanced machining processes and optimization
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Antibiotics Pharmacokinetics and Efficacy
  • Synthesis and Biological Evaluation
  • RNA and protein synthesis mechanisms
  • Metal Forming Simulation Techniques
  • Structural and Chemical Analysis of Organic and Inorganic Compounds
  • MicroRNA in disease regulation
  • Biosensors and Analytical Detection
  • Metallurgy and Material Forming
  • Insect and Pesticide Research
  • Metal and Thin Film Mechanics

South China University of Technology
2022-2024

State Key Laboratory of Mineral Processing
2023

Beijing General Research Institute of Mining and Metallurgy
2023

Beijing Forestry University
2019-2023

Xiangtan University
2005-2018

China Agricultural University
2010-2016

Institute of Molecular and Cell Biology
2016

Shandong Institute of Business and Technology
2015

Shihezi University
2015

Jingdong (China)
2014

MicroRNA (miRNA)-mediated silencing is a post-transcriptional mechanism that regulates translation of mRNAs primarily via their 3′-UTR. Ago2 binds miRNA directly and the core component miRNA-induced complex. GW182 another important factor in miRNA-mediated silencing, its interaction with evolutionarily conserved. However, GW182-Ago2 humans has not been characterized thoroughly, role mammalian pathway remains unclear. In current study, we generated set GST-, green fluorescence protein (GFP)-,...

10.1261/rna.1229409 article EN RNA 2009-03-26

This study aims to investigate the effect of a cationic-anionic mixed collector (dodecyltrimethyl ammonium bromide/sodium oleate (DTAB/NaOL) on selective separation apatite, dolomite, and potassium feldspar. Herein, several experimental methods, including flotation experiments, zeta-potential detection, microcalorimetry XPS analysis FTIR measurements, were used. The tests showed that dolomite feldspar can be successfully removed from apatite simultaneously when molar ratio DTAB NaOL was 2:1...

10.1016/j.ijmst.2022.12.013 article EN cc-by-nc-nd International Journal of Mining Science and Technology 2023-05-22

GW bodies, also known as mammalian P-bodies, are cytoplasmic foci involved in the post-transcriptional regulation of eukaryotic gene expression. Recently, bodies have been linked to RNA interference and demonstrated be important for short-interfering-RNA- microRNA-mediated mRNA decay translational repression. Evidence indicates that both passenger guide strands short-interfering duplexes can localize thereby indicating RNA-induced silencing complexes may activated within these centers....

10.1242/jcs.03429 article EN cc-by Journal of Cell Science 2007-03-31

Abstract In propellant systems, fuels of choice continue to be hydrazine and its derivatives, even though they comprise a class acutely carcinogenic toxic substances which exhibit rather high vapor pressures require expensive handling procedures costly safety precautions. Hypergolic ionic liquids tend have low volatility thermal chemical stability, often wide liquid ranges, could allow the use these as bipropellant under variety conditions. A new family borohydride borane–ionic‐liquid...

10.1002/ange.201309044 article EN Angewandte Chemie 2014-02-07

RNA interference is triggered by small interfering and microRNA, a potent mechanism in post-transcriptional regulation for gene expression. GW182 (also known as TNRC6A), an 182-kDa protein encoded TNRC6A, important this process, although details of its function remain unclear. Here, we report novel 210-kDa isoform human GW182, provisionally named trinucleotide GW1 (TNGW1) because it contains repeats mRNA sequence. TNGW1 was expressed independently present testis various cancer cells. Using...

10.1242/jcs.036905 article EN Journal of Cell Science 2008-12-03

A novel dispersive liquid–liquid microextraction ( DLLME ) method followed by HPLC analysis, termed sequential , was developed for the preconcentration and determination of aryloxyphenoxy‐propionate herbicides (i.e. haloxyfop‐R‐methyl, cyhalofop‐butyl, fenoxaprop‐P‐ethyl, fluazifop‐P‐butyl) in aqueous samples. The is based on combination ultrasound‐assisted with situ ionic liquid IL into one extraction procedure achieved better performance than widely used procedures. Chlorobenzene as...

10.1002/jssc.201200640 article EN Journal of Separation Science 2012-10-30

This study assessed the use of magnetic biosorbents in dispersive solid-phase extraction with a gas chromatograph-electron capture detector for determination trifluralin, chlorothalonil, transfluthrin, bromopropylate, and bifenthrin water samples. To our knowledge, this is first time that cork composites are used as an adsorbent extraction. The advantages include their density regulation high surface areas. can be recovered using field desorption purposes, which improve operation process...

10.1039/d3ay00163f article EN Analytical Methods 2023-01-01

Abstract A dispersive liquid–liquid microextraction (DLLME) method using in situ halide exchange reaction to form ionic liquid (IL) extraction phase was developed determine four insecticides (i.e. methoxyfenozide, tetrachlorvinphos, thiamethoxam, and diafenthiuron) water samples. The preconcentration procedure, followed by high‐performance chromatography variable wavelength detectors (VWD), enabled the formation of immiscible IL phase; were transferred into simultaneously, which enhanced...

10.1002/jssc.201100577 article EN Journal of Separation Science 2011-10-20

Adult-onset inherited myopathies with similar pathological features, including hereditary inclusion body myopathy (hIBM) and limb-girdle muscular dystrophy (LGMD), are a genetically heterogeneous group of muscle diseases. It is unclear whether these initiated by mutations in distinct classes genes etiologically related. Here, we exploit genetic model system to establish mechanistic link between diseases caused two genes, hnRNPA2B1 DNAJB6. Hrb98DE mrj the Drosophila melanogaster homologs...

10.1093/hmg/ddv627 article EN Human Molecular Genetics 2016-01-06

This paper presents a study of the performance ultrasound-enhanced temperature-controlled (UETC) ionic liquid dispersive liquid–liquid microextraction (IL-DLLME). The use ultrasonication and heating can enhance ability to extract analytes. Various parameters that would affect extraction efficiency, such as type volume dispersing solvents, salt concentration, pH value, centrifugation time, effect temperature on UETC-IL-DLLME, were investigated optimized. Under optimal conditions, good...

10.1039/c3ay25626j article EN Analytical Methods 2013-01-01

MicroRNA (miRNA)-mediated gene regulation has become a major focus in many biological processes. GW182 and its long isoform TNGW1 are marker proteins of GW/P bodies bind to Argonaute the RNA induced silencing complex. The goal this study is further define distinguish repression domain(s) human GW182/TNGW1. Two non-overlapping regions, Δ12 (amino acids 896–1219) containing Ago hook Δ5 1670–1962) RRM, both comparable tethering assay. Mapping data showed that RRM flanking sequences Δ5, but not...

10.1093/nar/gkq1099 article EN cc-by-nc Nucleic Acids Research 2010-12-02
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