Emily Ansusinha
- Kawasaki Disease and Coronary Complications
- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Streptococcal Infections and Treatments
- Neonatal Respiratory Health Research
- Neonatal and Maternal Infections
- Autism Spectrum Disorder Research
- Mosquito-borne diseases and control
- Birth, Development, and Health
- Bacterial Identification and Susceptibility Testing
- COVID-19 Impact on Reproduction
- Coronary Artery Anomalies
- Pneumonia and Respiratory Infections
- Mechanical Circulatory Support Devices
- Family and Disability Support Research
- Maternal Mental Health During Pregnancy and Postpartum
- COVID-19 Clinical Research Studies
- Cystic Fibrosis Research Advances
- COVID-19 and Mental Health
- Antibiotic Use and Resistance
- Otolaryngology and Infectious Diseases
- Antimicrobial Resistance in Staphylococcus
- Pediatric health and respiratory diseases
- Helicobacter pylori-related gastroenterology studies
- Diphtheria, Corynebacterium, and Tetanus
Children's National
2019-2025
Wake Forest University
2017-2024
George Washington University
2021
Despite worldwide spread of severe acute respiratory syndrome coronavirus-2, few publications have reported the potential for disease in pediatric population. We report 177 infected children and young adults, including 44 hospitalized 9 critically ill patients, with a comparison patient characteristics between nonhospitalized cohorts, as well noncritically cohorts. Children <1 year adolescents adults >15 years age were over-represented among patients (P = .07). Adolescents cohort .02).
Although intravenous immunoglobulin (IVIG) is effective therapy for Kawasaki disease, 10-20% of patients have recrudescent fever as a sign persistent inflammation and require additional treatment. We aimed to compare infliximab with second infusion IVIG treatment resistant disease.In this multicentre comparative effectiveness trial, (aged 4 weeks 17 years) disease at least 36 h after completion their first were recruited from 30 hospitals across the USA. Patients randomly assigned (1:1) (2...
Abstract Background Children and young adults were initially reported as largely spared from severe complications of SARS-CoV-2 infection, but the impact to this population has been significant. Methods This observational retrospective cohort study includes 420 symptomatic children with lab confirmed infection treated between March 15 June 16, 2020 at Children’s National Hospital in Washington DC. We identified compared cohorts non-hospitalized (N=324) hospitalized (N=96) patients, including...
<h3>Importance</h3> Public health measures implemented during the COVID-19 pandemic had widespread effects on population behaviors, transmission of infectious diseases, and exposures to environmental pollutants. This provided an opportunity study how these factors potentially influenced incidence Kawasaki disease (KD), a self-limited pediatric vasculitis unknown etiology. <h3>Objectives</h3> To examine change in KD across United States evaluate whether public affected prevalence KD....
Abstract Background Human parechovirus (PeVA) typically causes self-limiting respiratory and gastrointestinal infections. However, in infants, it can cause severe sepsis-like illness CNS disease. In 2022, a CDC Health Advisory reported PeVA infections young infants multiple states. Our aim was to describe the clinical features, laboratory characteristics, outcomes with infection during 2022 multistate outbreak. Methods A multicenter retrospective chart review conducted at 7 children’s...
Abstract Background The utility of follow-up blood cultures (FUBCs) in children with a gram-negative rod (GNR) bacteremia is unclear. A prior pediatric study showed that FUBC positivity rate was 21%. Many adult studies have demonstrated not always necessary the setting UTI. Primary objectives were to determine 1. follow up gram negative 2. To understand clinical risk factors associated bacteremia.Figure 1Flowchart depicting chart analysis Methods retrospective cohort patients &lt; 21...
Neurodevelopmental outcomes for preschool-age children in the United States with utero Zika virus (ZIKV) exposure have not yet been reported. We performed a case-control study to assess whether exposed ZIKV abnormal neurodevelopment at age 4–5 years compared unexposed controls. Thirteen ZIKV-exposed cases that did microcephaly or other specific features of congenital syndrome and 12 controls were evaluated between ages years. Child was assessed using Pediatric Evaluation Disability...
Comparing first and second wave MIS-C cohorts at our quaternary pediatric institution, were older, presented more frequently with shortness of breath, higher maximum troponin N-terminal BNP, required advanced respiratory inotropic support. Despite increased severity in the cohort, both had similar rates coronary artery abnormalities, systolic dysfunction, length stay.
BackgroundCulture-independent next generation sequencing has identified diverse microbial communities within the cystic fibrosis (CF) airway. The study objective was to test for differences in upper airway microbiome of children with CF and healthy controls age-related CF.MethodsOropharyngeal swabs clinical data were obtained from 25 50 aged ≤6 years. Bacterial DNA amplified sequenced V4 region 16S rRNA marker-gene. Alpha diversity measured using operational taxonomic units (OTUs), Shannon...
Background Extremely preterm (EP) birth is associated with higher risks of perinatal white matter (WM) injury, potentially causing abnormal neurologic and neurocognitive outcomes. MRI biomarkers distinguishing individuals without disorder guide research on EP antecedents, clinical correlates, prognoses. Purpose To compare multiparametric quantitative (qMRI) parameters EP-born adolescents autism spectrum disorder, cerebral palsy, epilepsy, or cognitive impairment (ie, atypically developing)...