Lisa Howley

ORCID: 0000-0002-3617-4331
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About
Contact & Profiles
Research Areas
  • Congenital Heart Disease Studies
  • Cardiovascular Issues in Pregnancy
  • Congenital Diaphragmatic Hernia Studies
  • Cardiac Valve Diseases and Treatments
  • Cardiac Arrhythmias and Treatments
  • Systemic Lupus Erythematosus Research
  • Prenatal Screening and Diagnostics
  • Pregnancy and preeclampsia studies
  • Congenital Anomalies and Fetal Surgery
  • Acute Myocardial Infarction Research
  • Blood groups and transfusion
  • Immunodeficiency and Autoimmune Disorders
  • Congenital heart defects research
  • Pregnancy and Medication Impact
  • Spinal Dysraphism and Malformations
  • Parvovirus B19 Infection Studies
  • Tumors and Oncological Cases
  • Phonocardiography and Auscultation Techniques
  • Infant Nutrition and Health
  • Receptor Mechanisms and Signaling
  • Gastroesophageal reflux and treatments
  • Gestational Trophoblastic Disease Studies
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Vascular Malformations and Hemangiomas
  • Maternal and Neonatal Healthcare

Children's Minnesota
2020-2025

Icahn School of Medicine at Mount Sinai
2024

Cohen Children's Medical Center
2024

University of Minnesota Children's Hospital
2023-2024

Children’s Minnesota - St. Paul Hospital
2020-2024

Minnesota West Community & Technical College
2024

Children's Hospital Colorado
2015-2023

Allina Health
2022-2023

University of Colorado Denver
2009-2023

University of Colorado Anschutz Medical Campus
2015-2023

Ebstein anomaly and tricuspid valve dysplasia are rare congenital malformations associated with high perinatal mortality. The literature consists of small, single-center case series spanning several decades. We performed a multicenter study to assess the outcomes factors mortality after fetal diagnosis in current era.Fetuses diagnosed from 2005 2011 were included 23 centers. primary outcome was mortality, defined as demise or death before neonatal discharge. Of 243 fetuses at mean...

10.1161/circulationaha.115.015839 article EN Circulation 2015-06-10

Prenatal detection (PND) has benefits for infants with hypoplastic left heart syndrome (HLHS) and transposition of the great arteries (TGA), but associations between sociodemographic geographic factors PND have not been sufficiently explored. This study evaluated whether socioeconomic quartile (SEQ), public insurance, race ethnicity, rural residence, distance residence (distance driving time from a cardiac surgical center) are associated or timing PND, secondary aim to analyze differences...

10.1161/circulationaha.120.053062 article EN Circulation 2021-05-17

Objective This prospective study of pregnant patients, S urveillance To P revent AV B lock L ikely to O ccur Q uickly (STOP BLOQ), addresses the impact anti‐SSA/Ro titers and utility ambulatory monitoring in detection fetal second‐degree atrioventricular block (AVB). Methods Women with autoantibodies by commercial testing were stratified into high low anti–52‐kD and/or 60‐kD SSA/Ro applying at‐risk thresholds defined previous evaluation AVB pregnancies. The high‐titer group performed heart...

10.1002/art.42733 article EN Arthritis & Rheumatology 2023-11-10

Abstract Background The benefits of early enteral feeding in neonates are well known and yet the optimal pre-operative nutrition prostaglandin-dependent infants with congenital cardiac disease remains ill-defined. This survey delineates international nutritional practices trends this population. Materials methods Paediatric practitioners responded to an Internet-based that explored assessment practices, criteria for readiness, medication dosing, concurrent umbilical catheters, observed...

10.1017/s1047951111001016 article EN Cardiology in the Young 2011-07-19

ace and ethnicity, socioeconomic status (SES), geography have been associated with differential outcomes in congenital heart disease death.In patients hypoplastic left syndrome (HLHS), lower SES has increased complications 1-year survival. 1o previous study examined how sociodemographics affect neonatal death among prenatally diagnosed HLHS.The goal was to investigate infants a prenatal diagnosis of HLHS understand associations between maternal patient characteristics hospital discharge...

10.1161/circulationaha.123.064476 article EN Circulation 2023-07-17

Objective To describe international surveillance and treatment strategies for managing anti-SSA/Ro autoantibody positive pregnancies.

10.1080/14767058.2024.2323623 article EN cc-by The Journal of Maternal-Fetal & Neonatal Medicine 2024-01-02

No evidence-based protocols exist for fetal cardiac monitoring during fetoscopic myelomeningocele (fMMC) repair and intraprocedural spectral Doppler data are limited. We determined the feasibility of continuous echocardiography fMMC correlated changes with qualitative function each phase repair.

10.1159/000538122 article EN Fetal Diagnosis and Therapy 2024-01-01

Twin-twin transfusion syndrome (TTTS) is a rare but serious cause of fetal cardiomyopathy with poorly understood pathophysiology and challenging prognostication. This study sought nonbiased, comprehensive assessment amniotic fluid (AF) microRNAs from TTTS pregnancies associations these miRNAs clinical characteristics. For the discovery cohort, AF ten fetuses severe were selected compared to normal singleton AF. Array panels assessing 384 performed on cohort controls. Using stringent q <...

10.3390/jcdd9020037 article EN cc-by Journal of Cardiovascular Development and Disease 2022-01-23

A female infant presented with bradycardia and an electrocardiogram demonstrating 2:1 atrioventricular depolarization, a prolonged QT interval, T wave alternans. After propranolol therapy was initiated, lidocaine challenge performed progressive shortening of the interval. This positive prompted clinical suspicion long syndrome type 3 (LQT3) early initiation mexiletine therapy. Subsequent genetic testing confirmed infant's diagnosis LQT3.

10.1111/j.1540-8159.2009.02550.x article EN Pacing and Clinical Electrophysiology 2009-09-30

Ebstein anomaly and tricuspid valve dysplasia (EA/TVD) carry high perinatal mortality. Past studies have focused on cardiac predictors of mortality; we sought to describe the fetal echo (FE) extracardiac Dopplers in this cohort determine their association with mortality.Fetuses EA/TVD at 23 centers from 2005-2011 were included for retrospective study. Doppler pattern velocity umbilical artery (UA), vein (UV), ductus venosus (DV), middle cerebral (MCA) collected. Bivariate multivariate...

10.1002/pd.5873 article EN Prenatal Diagnosis 2020-11-26

. Background: Third-degree atrioventricular block (AVB) is the most common manifestation of Anti-Ro antibody associated fetal cardiac disease. Extranodal findings isolated echogenicity, valvulitis with insufficiency and AV interval prolongation have been reported but not described in large prospective series. Aims: To report occurrence outcomes extranodal subjects followed prospectively since 2020 STOP BLOQ (Surveillance Treatment to Prevent Fetal Likely Occur Quickly) Registry for Neonatal...

10.1161/circ.150.suppl_1.4136984 article EN Circulation 2024-11-11

Background: Hypoplastic left heart syndrome (HLHS) is classified by subtype: mitral atresia and aortic (MA-AA), stenosis (MS-AA), (MS-AS). It controversial whether specific HLHS subtypes presence of ventriculocoronary connections (VCC) are associated with transplant-free survival. We aimed to determine there an increased risk mortality subtypes, this stratified the VCC, if a type stage I palliation in patients VCC improves also practice variation evaluation VCC. Methods: performed...

10.1161/circ.150.suppl_1.4138483 article EN Circulation 2024-11-12

Unguarded mitral valve orifice is a rare disease with only 7 described cases in the literature. We describe first known case of unguarded normal segmental cardiac anatomy, severe left ventricular dilatation and dysfunction, aortic atresia, atrial flutter. (Level Difficulty: Advanced.).

10.1016/j.jaccas.2020.11.020 article EN cc-by-nc-nd JACC Case Reports 2021-01-14
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