A5022702200- Congenital Heart Disease Studies
- Cardiovascular Issues in Pregnancy
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Congenital Diaphragmatic Hernia Studies
- Pulmonary Hypertension Research and Treatments
- Pregnancy and preeclampsia studies
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Coronary Artery Anomalies
- Mechanical Circulatory Support Devices
- Neonatal and fetal brain pathology
- Respiratory viral infections research
- Cardiac Structural Anomalies and Repair
- Vascular anomalies and interventions
- Kawasaki Disease and Coronary Complications
- Congenital Anomalies and Fetal Surgery
- Gestational Diabetes Research and Management
- Urological Disorders and Treatments
- Atrial Fibrillation Management and Outcomes
- Neonatal Respiratory Health Research
- Cardiac pacing and defibrillation studies
- Congenital heart defects research
- Cardiovascular Disease and Adiposity
- Birth, Development, and Health
Hospital Sant Joan de Déu Barcelona
2019-2024
Sant Joan de Déu Research Foundation
2022
Universitat de Barcelona
2020
Boston Children's Hospital
2014-2016
Universidad Pontificia Bolivariana
2014-2016
Harvard University
2014-2015
Boston Children's Museum
2014-2015
Boston University
2015
University of Utah
2015
Primary Children's Hospital
2015
Ebstein anomaly and tricuspid valve dysplasia are rare congenital malformations associated with high perinatal mortality. The literature consists of small, single-center case series spanning several decades. We performed a multicenter study to assess the outcomes factors mortality after fetal diagnosis in current era.Fetuses diagnosed from 2005 2011 were included 23 centers. primary outcome was mortality, defined as demise or death before neonatal discharge. Of 243 fetuses at mean...
Background During the severe acute respiratory syndrome Coronavirus 2 pandemic, there has been an increase in hyperinflammatory presentation previously healthy children with a variety of cardiac manifestations. Our objective is to describe manifestations found international cohort 55 pediatric cases multi‐system inflammatory during pandemic. Methods and Results We reviewed data on patients (≤18 years) structurally normal hearts who presented at hospitals United States, Kingdom, Spain,...
Objective To evaluate temporal trends in the prenatal diagnosis of transposition great arteries with intact ventricular septum (TGA/IVS) and its impact on neonatal morbidity mortality. Methods We included this study cohort newborns TGA/IVS who were referred for surgical management to our center over a 20-year period (1992–2011). The was divided into five 4-year periods primary outcome rate diagnosis. Secondary outcomes preoperative status perioperative survival. Results Of 340 patients...
ABSTRACT Objectives To better understand the natural history and spectrum of fetal aortic stenosis ( AS ), we aimed to (1) determine prenatal diagnosis rate neonates with critical a biventricular BV ) outcome, (2) describe findings at echocardiography in patients diagnosed prenatally. Methods A multicenter, retrospective study was performed on who presented were discharged outcome from 2000 2013. The compared that reported for hypoplastic left heart syndrome HLHS ). We reviewed...
Background In a recent multicenter study of perinatal outcome in fetuses with Ebstein anomaly or tricuspid valve dysplasia, we found that one third live-born patients died before hospital discharge. We sought to further describe postnatal management strategies and define risk factors for neonatal mortality circulatory at Methods Results This 23-center, retrospective from 2005 2011 included 243 dysplasia. Among patients, clinical echocardiographic were evaluated association palliated versus...
<b><i>Objectives:</i></b> Fetal right ventricular (RV) function assessment is challenging due to the RV geometry and limitations of in utero assessment. Postnatally, 2D echocardiographic fractional area change (FAC) used assess global systolic by calculating percentage from systole diastole. Reports on FAC are scarce prenatal life, nomograms throughout pregnancy not available. Our aims were (1) study feasibility reproducibility (2) construct for end-diastolic (ED)...
<b><i>Objectives:</i></b> Firstly, to describe the outcome of a series fetuses with Ebstein’s anomaly (EA) and, secondly, study utility different second-trimester echocardiographic parameters predict fetal and neonatal mortality. <b><i>Methods:</i></b> 39 EA diagnosed between 18 28 weeks gestation were included. Fetal echocardiography included cardiothoracic ratio (CTR); right atrial (RA) area index; displacement tricuspid valve (TV);...
Fetuses with congenital heart disease (CHD) have circulatory changes that may lead to predictable blood flow disturbances affect normal brain development. Hypoxemia and hypoperfusion alter the redox balance leading oxidative stress (OS), can be assessed measuring stable end-products. OS biomarkers (OSB) were measured in amniotic fluid fetuses (n = 41) without CHD 44) analyzed according aortic flow, expected cyanosis after birth, a classification derived from this. Birth head circumference...
Extrapulmonary manifestations of bronchiolitis have been previously studied, with some identifying right ventricle (RV) diastolic/systolic dysfunction. We hypothesized that severe cases would cardiac dysfunction resulting an increase in N-terminal pro-hormone B-type natriuretic peptide (NT-proBNP) values and worse outcomes. Therefore, the objective was to evaluate existence determine its association bronchiolitis.This prospective cohort study included children hospitalized for under 1-year...
The increase in the survival of patients with D-Transposition great arteries (TGA) after arterial switch operation (ASO) has now turned our focus to evaluation mid and long-term outcomes. Although most are followed by conventional echocardiography, study cardiac functionality morphometric parameters children TGA ASO is scarce. present aims describe functional echocardiographic changes ASO.We performed an observational aged 1-5 years who underwent neonatal ASO. Morphometric were analyzed 21...
The systolic (S) to diastolic (D) duration ratio (S/D) has been proposed as a useful index assess ventricular function in some pediatric cardiopathies. Prenatal reports on S/D are scarce and nomograms not available. We aimed establish normal values for left (LV) right (RV) ratios fetuses investigate its relation heart rate (HR), gestational age (GA) estimated fetal weight (EFW). Prospective cohort study including 602 low-risk singleton pregnancies (GA 18-41 weeks). Spectral Doppler signals...
Fetal echocardiography has limited prognostic ability in the evaluation of left-sided congenital heart defects (left defects). Cord blood cardiovascular biomarkers could improve left defects. A multicenter prospective cohort (2013−2019) including fetuses with (aortic coarctation, aortic stenosis, hypoplastic heart, and multilevel obstruction (complex defects) subdivided according to their outcome (favorable vs. poor), control were evaluated third trimester pregnancy at three referral centers...