A5054533758- Sirtuins and Resveratrol in Medicine
- Synthesis and Biological Evaluation
- Plant-derived Lignans Synthesis and Bioactivity
- Family Support in Illness
- Organometallic Compounds Synthesis and Characterization
- Marine Biology and Environmental Chemistry
- Bee Products Chemical Analysis
- Tryptophan and brain disorders
- Genomics, phytochemicals, and oxidative stress
- Maternal Mental Health During Pregnancy and Postpartum
- Cancer therapeutics and mechanisms
- Quinazolinone synthesis and applications
- Environmental Toxicology and Ecotoxicology
- Bioactive Compounds and Antitumor Agents
- Synthesis and biological activity
Mashhad University of Medical Sciences
2018-2019
The relationship between depression and increased oxidative stress is well known. DNA damage by oxidation factors an important cause of the aging process in psychiatric disorders.Owing to scarcity human studies high inconsistencies effects antidepressants on damage, current study was undertaken investigate its treatment damage.In a 15-week open-label citalopram (n = 25) sertraline 20), levels were measured comet assay, proinflammatory (Interlukin-6 (IL-6)) (8-hydroxy-2'-deoxyguanosine...
Abstract A new series of novel benzo[ c ]acridine‐diones possessing pharmacophoric elements antitubulins with central dihydropyridine bridge were designed and synthesized as potential anticancer agents tubulin polymerization inhibitors. The cytotoxic activity the compounds was evaluated against eight cancer cell lines including MCF‐7, A2780, HeLa, HepG2, DU145, A549, PC3, LNCAP cells normal human umbilical vein endothelial (HUVEC) through 3‐[4,5‐dimethylthiazol‐2‐yl]‐2,5‐diphenyl tetrazolium...
Trimethyltin (TMT) is a short-chain trialkyltin with various applications in industry. In addition, it known neurotoxin, producing significant and selective neurodegeneration the limbic system of both human animals. Recently, effect clavulanic acid (CA) nervous has been mentioned. Therefore, this study, role CA TMT-induced toxicity PC12 cells was evaluated. For were cultured exposed to different concentrations for 24 h. Then, TMT (20 µM) added cells. After that, MTT test performed assay...