- Reconstructive Surgery and Microvascular Techniques
- Breast Implant and Reconstruction
- Enhanced Recovery After Surgery
- Bone fractures and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Neuroscience and Neuropharmacology Research
- Tracheal and airway disorders
- Surgical site infection prevention
- Neuroinflammation and Neurodegeneration Mechanisms
- Anesthesia and Pain Management
- Neurogenesis and neuroplasticity mechanisms
- Wound Healing and Treatments
- Orthopedic Infections and Treatments
- Anesthesia and Neurotoxicity Research
- Cardiac and Coronary Surgery Techniques
- Nerve injury and regeneration
- Nerve Injury and Rehabilitation
- Mesenchymal stem cell research
- Anatomy and Medical Technology
- Skin and Cellular Biology Research
- Dermatologic Treatments and Research
- Tissue Engineering and Regenerative Medicine
- Diabetic Foot Ulcer Assessment and Management
- Breast Cancer Treatment Studies
- Hip and Femur Fractures
Rigshospitalet
2015-2024
Copenhagen University Hospital
2011-2024
Odense University Hospital
2000-2024
University of Southern Denmark
2002-2023
University of Copenhagen
2016-2022
Capital Region of Denmark
2015-2017
Danish Breast Cancer Cooperative Group
2017
Creative Commons
2017
Breast Center
2015
Amager Hospital
2001
Using repeated positron emission tomography (PET) measures of regional cerebral counts, we investigated the cortical activations induced in eight normal subjects performing different frequencies fingertapping (0.5-4 Hz) with right index finger. The task was auditorially cued and performance recorded during scanning procedure. Performance evaluation showed increased error rates, fingertapping, high low frequencies, best tapping measured midrange frequencies. Significantly activated areas (p <...
The concept of fast-track surgery (FTS) is a peri- and postoperative care developed to reduce length hospital stay (LOS) morbidity after surgery. FTS programmes have been reported from other surgical specialities, but there are few reports in plastic surgery.Autologous breast reconstructions performed with abdominal free flaps since 1994. In 2006, an program was introduced. Important changes procedure were: early mobilisation, fewer/faster removal drains urinary catheter, discontinuation...
Cerebral ischemic stroke is a leading cause of morbidity and mortality globally. However, the mechanisms underlying injury remain poorly understood. Here, it found that deficiency ubiquitin-specific protease USP25 significantly aggravate in mice. has no impact on neuronal death under hypoxic conditions, but reduced stroke-induced loss neurological deficits by inhibiting microglia-mediated neuroinflammation. Mechanistically, restricts activation NF-κB MAPK signaling regulating TAB2. As...
Summary: The authors recently showed that fast-track surgery could reduce the length of stay after a deep inferior epigastric perforator flap procedure from 7.4 days to 6.2 without increasing complication rates or loss. This study improves protocol and identifies specific factors kept patients in hospital. present their results first 16 consecutive cases. Multimodal opioid-sparing analgesia was used. Nurses removed suction drains, consulting doctors. Fulfilment functional discharge criteria...
Rheumatoid meningitis is a rare extra-articular manifestation of rheumatoid arthritis, often with non-specific symptoms. In most cases brain MRI shows patchy lepto- and pachymeningeal enhancement, but the diagnosis currently relies on examination meningeal biopsy presence plasma cells noduli. Presence IgM rheumatic factor (RF) has been found in several recently four have shown high titer anti-cyclic citrullinated peptide (anti-CCP) CSF, suggesting this as potential marker for meningitis. We...
About 30% of patients with active acromegaly experience paradoxically increased growth hormone (GH) secretion during the diagnostic oral glucose tolerance test (OGTT). Endogenous glucose-dependent insulinotropic polypeptide (GIP) is implicated in this paradoxical secretion.
The potential neuroprotective effects of glial cell line-derived neurotrophic factor (GDNF) and neublastin (NBN) against NMDA-induced excitotoxicity were examined in hippocampal brain slice cultures. Recombinant human GDNF (25–100 ng/ml) or NBN, medium conditioned by growth transfected, NBN-producing HiB5 cells, added to cultures 1 h before exposure 10 μM NMDA for 48 h. Neuronal death was monitored, during the exposure, densitometric measurements propidium iodide (PI) uptake loss Nissl...
We have done a total of 292 breast reconstructions using free flap over period 10 years (1994–2003). During the last five number deep inferior epigastric perforator (DIEP) flaps has increased. However, to secure an optimal blood supply we still use muscle-sparing transverse rectus abdominis musculocutaneous (TRAM) sometimes. Our results with two were identical as far operating time and length hospital stay concerned, but DIEP less donor site morbidity. are influenced by our selection...
Mucosal melanoma of the oral cavity is a rare but highly aggressive neoplasm. However, clinicians need to be aware other and more frequent etiologies intraoral pigmentation, such as amalgam tattoos. As has been extensively used for dental restorations can cause pigmentations in mucosa, this differential diagnosis not forgotten. We describe characteristics these two phenomena present case vignette illustrating diagnostic issues. Other causes pigmentation are summarized.
Background: Indocyanine green angiography (ICG-A) is a valuable tool in assessment of intraoperative tissue perfusion autologous breast reconstruction (ABR). This study evaluated the effectiveness ICG-A guiding surgical decision-making and its correlation with postoperative complications. Methods: A prospective observational was conducted including 36 patients undergoing immediate or delayed ABR using pedicled latissimus dorsi (pLD) deep inferior epigastric perforator (DIEP) flaps. assessed...