A5055993827- Genetic diversity and population structure
- Plant and animal studies
- Plant Reproductive Biology
- Plant Parasitism and Resistance
- Chromosomal and Genetic Variations
- Genetic Mapping and Diversity in Plants and Animals
- Ecology and Vegetation Dynamics Studies
- Plant Pathogens and Resistance
- Genetic and Environmental Crop Studies
- Botany, Ecology, and Taxonomy Studies
- Evolution and Genetic Dynamics
- Genetic and phenotypic traits in livestock
- Plant Taxonomy and Phylogenetics
- Plant Pathogens and Fungal Diseases
- Plant and Fungal Species Descriptions
- Animal Behavior and Reproduction
- Rangeland and Wildlife Management
- Genomics and Phylogenetic Studies
- Mycorrhizal Fungi and Plant Interactions
- Insect and Arachnid Ecology and Behavior
- Advances in Cucurbitaceae Research
- Carcinogens and Genotoxicity Assessment
- Nuclear physics research studies
- Magnetic Bearings and Levitation Dynamics
- Advanced Mathematical Theories and Applications
University of Montana
2014-2024
Claremont Colleges
2020
Duke University
2000-2016
University of Georgia
2015-2016
Oregon State University
2015-2016
Genetic Alliance
2015-2016
American Genetic Association
2015-2016
Princeton University
1999-2001
Atomic Energy (Canada)
1976
Female meiotic drive, in which paired chromosomes compete for access to the egg, is a potentially powerful but rarely documented evolutionary force. In interspecific monkeyflower (Mimulus) hybrids, driving M. guttatus allele (D) exhibits 98:2 transmission advantage via female meiosis. We show that extreme drive most likely caused by divergence centromere-associated repeat domains and document cytogenetic functional polymorphism within population of guttatus. conspecific crosses, D had 58:42...
Abstract As part of a study the genetics floral adaptation and speciation in Mimulus guttatus species complex, we constructed genetic linkage map an interspecific cross between M. nasutus. We genotyped F2 mapping population (N = 526) at 255 AFLP, microsatellite, gene-based markers derived framework through repeated rounds ordering marker elimination. The final consists 174 loci on 14 groups with total length 1780 cM Kosambi. Genome estimates (2011–2096 cM) indicate that this provides...
The genetic basis of species differences provides insight into the mode and tempo phenotypic divergence. We investigate floral between two closely related plant taxa with highly divergent mating systems,Mimulus guttatus (large‐flowered outcrosser) andM. nasutus (small‐flowered selfer). had previously constructed a framework linkage map hybrid genome containing 174 markers spanning approximately 1800 cM on 14 groups. In this study, we analyze genetics 16 floral, reproductive, vegetative...
Ecological factors that reduce the effectiveness of cross-pollination are likely to play a role in frequent evolution routine self-fertilization flowering plants. However, we lack empirical evidence linking reproductive assurance value selfing poor pollination environments evolutionary shifts mating system. Here, investigated adaptive significance prior polymorphic annual plant Arenaria uniflora (Caryophyllaceae), which selfer populations occur only areas range overlap with congener A....
Abstract We report the discovery, mapping, and characterization of a meiotic drive locus (D) exhibiting nearly 100% nonrandom transmission in hybrids between two species yellow monkeyflowers, outcrossing Mimulus guttatus selfing M. nasutus. Only 1% F2 were nasutus homozygotes at marker most tightly linked to D. used set reciprocal backcrosses distinguish among male-specific, female-specific, zygote-specific sources ratio distortion. Transmission was severely distorted only when heterozygous...
Abstract Much evidence has shown that postzygotic reproductive isolation (hybrid inviability or sterility) evolves by the accumulation of interlocus incompatibilities between diverging populations. Although in theory only a single pair incompatible loci is needed to isolate species, empirical work Drosophila revealed hybrid fertility problems often are highly polygenic and complex. In this article we investigate genetic basis sterility two closely related species monkeyflower, Mimulus...
In flowering plants, pollen limitation has been proposed to intensify selection on floral characters important in pollinator attraction, but may also select for traits that increase seed set through autonomous selfing. Here, a factorial design (+/- addition, +/- removal) was used investigate how the pollination environment affects morphology via female fitness mixed-mating population of yellow monkeyflower, Mimulus guttatus (Phrymaceae). Female strongly pollen-limited, with supplementally...
Chromosomal rearrangements may directly cause hybrid sterility and can facilitate speciation by preserving local adaptation in the face of gene flow. We used comparative linkage mapping with shared gene-based markers to identify potential chromosomal between sister monkeyflowers Mimulus lewisii cardinalis, which are textbook examples ecological speciation. then remapped quantitative trait loci (QTLs) for floral traits flowering time (premating isolation) (postzygotic isolation). identified...
Inferences about past processes of adaptation and speciation require a gene-scale genome-wide understanding the evolutionary history diverging taxa. In this study, we use capture nuclear gene sequences, plus skimming organellar to investigate phylogenomics monkeyflowers in Mimulus section Erythranthe (27 accessions from seven species). Taxa within Erythranthe, particularly parapatric putatively sister species M. lewisii (bee-pollinated) cardinalis (hummingbird-pollinated), have been model...
Multilocus interactions (also known as Dobzhansky-Muller incompatibilities) are thought to be the major source of hybrid inviability and sterility. Because cytoplasmic nuclear genomes have conflicting evolutionary interests often highly coevolved, cytonuclear incompatibilities may among first develop in incipient species. Here, we report discovery cytoplasm-dependent anther sterility hybrids between closely related Mimulus species, outcrossing M. guttatus selfing nasutus. A novel pollenless...
Multilocus interactions (also known as Dobzhansky‐Muller incompatibilities) are thought to be the major source of hybrid inviability and sterility. Because cytoplasmic nuclear genomes have conflicting evolutionary interests often highly coevolved, cytonuclear incompatibilities may among first develop in incipient species. Here, we report discovery cytoplasm‐dependent anther sterility hybrids between closely related Mimulus species, outcrossing M. guttatus selfing nasutus. A novel pollenless...
Characterizing the genetic and molecular basis of hybrid incompatibilities is a first step toward understanding their evolutionary origins. We fine mapped nuclear restorer (Rf) cytoplasm-dependent anther sterility in Mimulus hybrids by identifying targeting regions guttatus genome containing large numbers candidate pentatricopeptide repeat genes (PPRs). The single Mendelian locus Rf was isolated to 1.3-cM region on linkage group 7 that spans genome's largest cluster PPRs, then split into two...
Female meiotic drive, in which chromosomal variants preferentially segregate to the egg pole during asymmetric female meiosis, is a theoretically pervasive but still mysterious form of selfish evolution. Like other genetic elements, driving chromosomes may be maintained as balanced polymorphisms by pleiotropic or linked fitness costs. A centromere-associated driver (D) with ∼58:42 female-specific transmission advantage occurs at intermediate frequency (32–40%) Iron Mountain population yellow...
In flowering plants, F1 hybrid seed lethality is a common outcome of crosses between closely related diploid species, but the genetic basis this early-acting and potentially widespread form postzygotic reproductive isolation largely unknown. We intercrossed two species monkeyflower, Mimulus guttatus tilingii, to characterize mechanisms strength isolation. Then, using reciprocal backcross design, we performed high-resolution mapping determine architecture directly test for loci with...
The fundamental asymmetry of female meiosis creates an arena for genetic elements to compete inclusion in the egg, promoting selfish evolution centromere variants that maximize their transmission future egg. Such "female meiotic drive" has been hypothesized explain paradoxically complex and rapidly evolving nature centromeric DNA proteins. Although theoretically widespread, few cases active drive have observed, thereby limiting opportunities directly assess impact on molecular variation at...
Chromosomal rearrangements can contribute to the evolution of postzygotic reproductive isolation directly, by disrupting meiosis in F1 hybrids, or indirectly, suppressing recombination among genic incompatibilities. Because direct effects on fertility imply fitness costs during their spread, understanding mechanism hybrid sterility is integral reconstructing role(s) speciation. In hybrids between monkeyflowers Mimulus cardinalis and lewisii, contain all quantitative trait loci (QTLs) for...
Abstract Polymorphic chromosomal rearrangements can bind hundreds of genes into single genetic loci with diverse effects. Rearrangements are often associated local adaptation and speciation may also be an important component variation within populations. We genetically phenotypically characterize a segregating inversion (inv6) in the Iron Mountain (IM) population Mimulus guttatus (yellow monkeyflower). initially mapped inv6 as region recombination suppression three F2 populations resulting...
Intraspecific coevolution between selfish elements and suppressors may promote interspecific hybrid incompatibility, but evidence of this process is rare. Here, we use genomic data to test alternative models for the evolution cytonuclear male sterility in Mimulus In hybrids Iron Mountain (IM) guttatus × nasutus, two tightly linked M. alleles (Rf1/Rf2) each restore fertility by suppressing a local mitochondrial male-sterility gene (IM-CMS). Unlike neutral incompatibility loci, predicts that...