A5018298075- Lymphatic System and Diseases
- Diagnosis and Treatment of Venous Diseases
- Body Contouring and Surgery
- Systemic Sclerosis and Related Diseases
- Surgical site infection prevention
- Wound Healing and Treatments
- Pressure Ulcer Prevention and Management
- Reconstructive Surgery and Microvascular Techniques
Turku University Hospital
2021-2024
University of Turku
2024
Creative Commons
2022
Background Upper limb lymphedema is a common problem after axillary lymph node dissection. Lymphatic drainage can be improved by microvascular transfer, whereas liposuction used to reduce arm volume and excess of adipose tissue. We present the results chronic patients who have undergone transfer simultaneously in 1 operation compare with without liposuction. Methods During May 2007 February 2015, 20 postmastectomy Hodgkin's lymphoma patient presenting nonpitting (age between 37 74 years,...
BACKGROUND: Breast cancer-related lymphedema (BCRL) is a common complication lacking medical treatment. Lymfactin® an adenovirus type 5-based gene therapy and prolymphangiogenic growth factor vector that induces vascular endothelial C (VEGF-C) expression. Our aim was to evaluate the therapeutic effect of Lymfactin ® with vascularized lymph node transfer (VLNT). METHODS: This Phase II, double-blind, placebo-controlled, randomized multicenter study evaluated efficacy safety in combination...
Our objective was to analyze whether a correlation could be observed between preoperative factors and microvascular lymph node transfer outcome after long-term follow-up.We included 67 patients in this retrospective case series. The incidence of cellulitis, the difference arm circumference, use compression garments both preoperatively postoperatively, subjective symptoms, such as pain, were analyzed. Volumetry lymphoscintigraphy results also analyzed subgroup patients. We correlated with...
Vascularized lymph node transfer surgery (VLNT) can provide benefit to lymphedema patients. Cytokines may play a role in the development of and regeneration lymphatic vessels after VLNT. Our primary aim was investigate whether VLNT patients have specific cytokine profile. secondary see preoperative or severity affects postoperative response. Wound exudate gathered from 18 undergoing on first sixth day (POD). The concentrations IL-10, TNF-α, TGF-β1 VEGF-C were analyzed using enzymelinked...
PurposeSurgical site infection (SSI) after axillary lymph node dissection (ALND) for breast cancer increases morbidity and delays the onset of adjuvant treatment. Only a few studies have investigated feasibility wound exudate analysis in SSI prediction. This study assessed changes cytokine levels postsurgical ALND examined their predictive value early diagnosis SSI.MethodsAn observational prospective pilot was conducted 47 patients with undergoing ALND. Wound samples were collected on first...
INTRODUCTION: Vascularized lymph node transfer surgery (VLNT) can provide benefit to lymphedema patients. Cytokines may play a role in the development of and regeneration lymphatic vessels after VLNT. Previous studies have implied that could partly be caused by an immunological response towards Th2 shift (Zampell JC et al. Am J Physiol - Cell Physiol. 2012.; Ristimaki A al., Biol Chem. 1998). Our primary aim was investigate whether VLNT patients specific cytokine profile. secondary see...