A5037225006- Ionosphere and magnetosphere dynamics
- Solar and Space Plasma Dynamics
- Geomagnetism and Paleomagnetism Studies
- Earthquake Detection and Analysis
- Planetary Science and Exploration
- GNSS positioning and interference
- Astro and Planetary Science
- Space Science and Extraterrestrial Life
- Folate and B Vitamins Research
- Metabolomics and Mass Spectrometry Studies
- Genetic Mapping and Diversity in Plants and Animals
- Gene expression and cancer classification
- Alzheimer's disease research and treatments
- Microbial Metabolic Engineering and Bioproduction
- Advanced Computational Techniques and Applications
- Sensor Technology and Measurement Systems
- Radar Systems and Signal Processing
- Electron and X-Ray Spectroscopy Techniques
- History and Developments in Astronomy
- Advanced Measurement and Detection Methods
- Advanced SAR Imaging Techniques
- Geophysical and Geoelectrical Methods
- Radio Astronomy Observations and Technology
- RNA modifications and cancer
- Psoriasis: Treatment and Pathogenesis
University of Manchester
1959-2024
University of Exeter
2013
Worcestershire Royal Hospital
1971-1981
Electronics and Radar Development Establishment
1968-1975
Aberystwyth University
1973
University College London
1970
SKA Observatory
1959-1965
Experimental Station
1959
Biofuels are the most immediate, practical solution for mitigating dependence on fossil hydrocarbons, but current biofuels (alcohols and biodiesels) require significant downstream processing not fully compatible with modern, mass-market internal combustion engines. Rather, ideal structurally chemically identical to fuels they seek replace (i.e., aliphatic n - iso -alkanes -alkenes of various chain lengths). Here we report production such petroleum-replica hydrocarbons in Escherichia coli ....
The global dietary supplement market is valued at over USD 100 billion. One popular supplement, S-adenosylmethionine, marketed to improve joints, liver health and emotional well-being in the US since 1999, has been a prescription drug Europe treat depression arthritis 1975, but recent studies questioned its efficacy. In our body, S-adenosylmethionine critical for methylation of nucleic acids, proteins many other targets. marketing SAM implies that more better it would stimulate methylations...
Parkinson's disease (PD) is one of the most common neurodegenerative diseases, commonly characterised by motor dysfunction, but also with a high prevalence cognitive decline in decades following diagnosis-a condition known as dementia (PDD). Although several metabolic disruptions have been identified PD, there has yet to be multi-regional analysis multiple metabolites conducted PDD brains. This discovery study attempts address this gap knowledge. A semi-targeted liquid chromatography-mass...
Observations at two closely spaced frequencies of the Faraday rotation moon-reflected radio waves are described. These measurements have provided accurate values for total electron content ionosphere many hours on successive days. The observations reported here span a period one month during winter 1960. Short-period fluctuations were observed. about 2 to 3% in amplitude and occurred chiefly day-time. gross shape F region as determined by ratio number electrons above peak below was roughly...
Abstract The combination of multi-omic techniques, such as genomics, transcriptomics, proteomics, metabolomics and epigenomics, has revolutionised studies in medical research. These techniques are employed to support biomarker discovery, better understand molecular pathways identify novel drug targets. Despite concerted efforts integrating omic datasets, there is an absence protocols that integrate all four biomolecules a single extraction process. Here, we demonstrate for the first time...
The feeding/fasting cycles controlled by our circadian clock impose great daily metabolic and physiological changes, yet investigations into the consequences of deficiencies, either dietary or genetic, have often ignored time day animals subjects. In addition, these deficiencies may themselves disrupt clock, causing secondary metabolic, behavioural disorders. Dietary methionine/choline deficiency in rodents is a common model for human non-alcoholic steatohepatitis, but methionine choline are...
Abstract Aims The aryl hydrocarbon receptor (AhR) is a ligand-activated implicated in many inflammatory disorders. skin microbiota plays crucial role maintaining epidermal barrier integrity and thought to modulate homeostasis partly through the production of AhR ligands, including metabolites microbial tryptophan metabolism such as indole derivatives. Here, we report that activate their unique metabolite profiles. Methods results Of bacteria isolated from healthy human screened for ability...
The UK incoherent scatter system operates in two modes. monostatic pulsed has been operation since 1968, and a summary of the results obtained this mode is given. full multistatic CW operating September 1972 among preliminary are measurements total vector velocity drift.
Measurements of the electron content ionosphere obtained from observations differential Faraday rotation moon-reflected signals on two closely spaced frequencies are described. Accurate values many successive days near summer solstices 1960 and 1961 presented, compared contrasted with similar measurements made in winter (Evans & Taylor 1961). The diurnal variations content, short-period irregular fluctuations equivalent slab thickness top-to-bottom ratio all found to differ those...