A5066281911- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- Cardiovascular Effects of Exercise
- Pericarditis and Cardiac Tamponade
- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Vitamin D Research Studies
- Clostridium difficile and Clostridium perfringens research
- Antimicrobial Peptides and Activities
Deutsches Herzzentrum der Charité
2023-2024
Charité - Universitätsmedizin Berlin
2019-2024
Freie Universität Berlin
2019-2023
Humboldt-Universität zu Berlin
2019-2023
Background Inflammatory cardiomyopathy is one of the most common causes sudden cardiac death in young adults. Diagnosis inflammatory remains challenging, and better monitoring tools are needed. We present magnetocardiography as a method to diagnose myocardial inflammation monitor treatment response. Methods Results A total 233 patients were enrolled, with mean age 45 (±18) years, 105 (45%) women. The primary analysis included 209 adult subjects, whom 66 (32%) diagnosed cardiomyopathy, 17...
Infiltration of the myocardium with various cell types, cytokines and chemokines plays a crucial role in pathogenesis cardiomyopathies including inflammatory myocarditis. A more comprehensive understanding precise immune mechanisms involved acute chronic myocarditis is essential to develop novel therapeutic approaches. This review offers overview current knowledge landscape based on etiology. It identifies gaps our about cardiac inflammation emphasizes need for new translational approaches...
Amyloidosis is characterized by a disorder of protein conformation and metabolism, resulting in deposits insoluble fibrils various organs causing functional disturbances. can also affect the heart. Cardiac amyloidosis tends to have poor prognostic outcome if diagnosed at late stage. Therefore, early diagnosis initiation therapy as well monitoring treatment response are crucial improve outcomes learn more about its pathophysiology clinical course. We present an 83-year-old woman with cardiac...
The diagnosis of inflammatory cardiomyopathies remains challenging. Life-threatening conditions such as acute coronary syndrome (ACS) always have to be considered differential diagnoses due similarities in presentation. Diagnostic methods for cardiomyopathy include endomyocardial biopsy (EMB), cardiac magnetic resonance imaging (CMR), and positron emission tomography-computed tomography (PET-CT). We report a case whom magnetocardiography (MCG) led an initial MCG was used subsequent...
ABSTRACT Background Despite currently available state-of-the art therapies, a substantial proportion of patients with inflammatory cardiomyopathy progresses to advanced heart failure. There is an urgent need for novel therapies improve outcomes. We hypothesized that elevated cyto-kine levels in may lead cardiac injury and specific cyto-kines are associated severely decreased left ventricular function consequently, thereby suggesting their potential as therapeutic targets. Methods Results...